| Full name: DMRT like family A1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 9p21.3 | ||
| Entrez ID: 63951 | HGNC ID: HGNC:13826 | Ensembl Gene: ENSG00000176399 | OMIM ID: 614803 |
| Drug and gene relationship at DGIdb | |||
Expression of DMRTA1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DMRTA1 | 63951 | 244725_at | -0.1716 | 0.6174 | |
| GSE26886 | DMRTA1 | 63951 | 244725_at | 0.1129 | 0.4317 | |
| GSE45670 | DMRTA1 | 63951 | 244725_at | -0.1475 | 0.1718 | |
| GSE53622 | DMRTA1 | 63951 | 20507 | -1.9067 | 0.0000 | |
| GSE53624 | DMRTA1 | 63951 | 20507 | -1.9270 | 0.0000 | |
| GSE63941 | DMRTA1 | 63951 | 244725_at | 0.0663 | 0.7078 | |
| GSE77861 | DMRTA1 | 63951 | 244725_at | -0.0280 | 0.8748 | |
| GSE97050 | DMRTA1 | 63951 | A_23_P413923 | -0.3382 | 0.6443 | |
| SRP007169 | DMRTA1 | 63951 | RNAseq | -0.8807 | 0.3209 | |
| SRP064894 | DMRTA1 | 63951 | RNAseq | -1.1327 | 0.0171 | |
| SRP133303 | DMRTA1 | 63951 | RNAseq | -0.8478 | 0.2013 | |
| SRP193095 | DMRTA1 | 63951 | RNAseq | -1.3372 | 0.0037 | |
| SRP219564 | DMRTA1 | 63951 | RNAseq | -2.5586 | 0.0016 | |
| TCGA | DMRTA1 | 63951 | RNAseq | -0.8195 | 0.0584 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by DMRTA1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DMRTA1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DMRTA1 | 63951 | 2 | 17 | 11 | |
| GSE20123 | DMRTA1 | 63951 | 2 | 17 | 11 | |
| GSE43470 | DMRTA1 | 63951 | 1 | 15 | 27 | |
| GSE46452 | DMRTA1 | 63951 | 4 | 24 | 31 | |
| GSE47630 | DMRTA1 | 63951 | 1 | 23 | 16 | |
| GSE54993 | DMRTA1 | 63951 | 8 | 0 | 62 | |
| GSE54994 | DMRTA1 | 63951 | 5 | 19 | 29 | |
| GSE60625 | DMRTA1 | 63951 | 3 | 0 | 8 | |
| GSE74703 | DMRTA1 | 63951 | 1 | 12 | 23 | |
| GSE74704 | DMRTA1 | 63951 | 0 | 13 | 7 | |
| TCGA | DMRTA1 | 63951 | 9 | 54 | 33 |
Total number of gains: 36; Total number of losses: 194; Total Number of normals: 258.
Somatic mutations of DMRTA1:
Generating mutation plots.
Highly correlated genes for DMRTA1:
Showing top 20/187 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DMRTA1 | PTGER3 | 0.741539 | 3 | 0 | 3 |
| DMRTA1 | RNF31 | 0.738465 | 3 | 0 | 3 |
| DMRTA1 | ZNF334 | 0.728887 | 3 | 0 | 3 |
| DMRTA1 | SARDH | 0.724658 | 4 | 0 | 4 |
| DMRTA1 | CLMP | 0.708638 | 3 | 0 | 3 |
| DMRTA1 | HAS1 | 0.700525 | 3 | 0 | 3 |
| DMRTA1 | ENTPD2 | 0.693914 | 3 | 0 | 3 |
| DMRTA1 | PNMT | 0.691129 | 3 | 0 | 3 |
| DMRTA1 | SNRK | 0.684046 | 4 | 0 | 4 |
| DMRTA1 | CISD3 | 0.683947 | 3 | 0 | 3 |
| DMRTA1 | ARHGEF15 | 0.683374 | 3 | 0 | 3 |
| DMRTA1 | SEMA3A | 0.68126 | 3 | 0 | 3 |
| DMRTA1 | SLC26A10 | 0.680044 | 4 | 0 | 3 |
| DMRTA1 | EPN1 | 0.674207 | 3 | 0 | 3 |
| DMRTA1 | GAL3ST1 | 0.673795 | 3 | 0 | 3 |
| DMRTA1 | TCEA2 | 0.662308 | 3 | 0 | 3 |
| DMRTA1 | TRIM6 | 0.654345 | 3 | 0 | 3 |
| DMRTA1 | REXO1 | 0.654111 | 3 | 0 | 3 |
| DMRTA1 | KLHL31 | 0.653138 | 4 | 0 | 3 |
| DMRTA1 | COPS2 | 0.653077 | 3 | 0 | 3 |
For details and further investigation, click here
