| Full name: SNF related kinase | Alias Symbol: FLJ20224|HSNFRK|KIAA0096 | ||
| Type: protein-coding gene | Cytoband: 3p22.1 | ||
| Entrez ID: 54861 | HGNC ID: HGNC:30598 | Ensembl Gene: ENSG00000163788 | OMIM ID: 612760 |
| Drug and gene relationship at DGIdb | |||
Expression of SNRK:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SNRK | 54861 | 209481_at | -0.5880 | 0.1823 | |
| GSE20347 | SNRK | 54861 | 209481_at | -0.9308 | 0.0000 | |
| GSE23400 | SNRK | 54861 | 209481_at | -0.6731 | 0.0000 | |
| GSE26886 | SNRK | 54861 | 209481_at | -1.3018 | 0.0000 | |
| GSE29001 | SNRK | 54861 | 209481_at | -0.8291 | 0.0031 | |
| GSE38129 | SNRK | 54861 | 209481_at | -0.9553 | 0.0000 | |
| GSE45670 | SNRK | 54861 | 209481_at | -0.4568 | 0.0052 | |
| GSE53622 | SNRK | 54861 | 49533 | -0.9213 | 0.0000 | |
| GSE53624 | SNRK | 54861 | 49533 | -1.2255 | 0.0000 | |
| GSE63941 | SNRK | 54861 | 209481_at | -0.6978 | 0.0335 | |
| GSE77861 | SNRK | 54861 | 209481_at | -0.5155 | 0.1629 | |
| GSE97050 | SNRK | 54861 | A_23_P211985 | -0.6613 | 0.0903 | |
| SRP007169 | SNRK | 54861 | RNAseq | -0.7966 | 0.0411 | |
| SRP008496 | SNRK | 54861 | RNAseq | -0.6317 | 0.0212 | |
| SRP064894 | SNRK | 54861 | RNAseq | -0.7064 | 0.0056 | |
| SRP133303 | SNRK | 54861 | RNAseq | -0.5195 | 0.0035 | |
| SRP159526 | SNRK | 54861 | RNAseq | -0.8491 | 0.0024 | |
| SRP193095 | SNRK | 54861 | RNAseq | -0.8560 | 0.0000 | |
| SRP219564 | SNRK | 54861 | RNAseq | -0.7132 | 0.0140 | |
| TCGA | SNRK | 54861 | RNAseq | -0.2695 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by SNRK expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SNRK:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SNRK | 54861 | 0 | 19 | 11 | |
| GSE20123 | SNRK | 54861 | 0 | 19 | 11 | |
| GSE43470 | SNRK | 54861 | 0 | 21 | 22 | |
| GSE46452 | SNRK | 54861 | 2 | 17 | 40 | |
| GSE47630 | SNRK | 54861 | 1 | 24 | 15 | |
| GSE54993 | SNRK | 54861 | 7 | 2 | 61 | |
| GSE54994 | SNRK | 54861 | 1 | 34 | 18 | |
| GSE60625 | SNRK | 54861 | 5 | 0 | 6 | |
| GSE74703 | SNRK | 54861 | 0 | 16 | 20 | |
| GSE74704 | SNRK | 54861 | 0 | 13 | 7 | |
| TCGA | SNRK | 54861 | 1 | 72 | 23 |
Total number of gains: 17; Total number of losses: 237; Total Number of normals: 234.
Somatic mutations of SNRK:
Generating mutation plots.
Highly correlated genes for SNRK:
Showing top 20/1532 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SNRK | RNF185 | 0.780608 | 3 | 0 | 3 |
| SNRK | FYCO1 | 0.754425 | 11 | 0 | 11 |
| SNRK | FCHO2 | 0.753203 | 7 | 0 | 7 |
| SNRK | KCMF1 | 0.744907 | 4 | 0 | 3 |
| SNRK | CA13 | 0.740208 | 3 | 0 | 3 |
| SNRK | KAT2B | 0.7393 | 12 | 0 | 11 |
| SNRK | AFF1 | 0.73008 | 7 | 0 | 7 |
| SNRK | STK39 | 0.726014 | 10 | 0 | 10 |
| SNRK | ACAA1 | 0.723384 | 8 | 0 | 8 |
| SNRK | BBIP1 | 0.722584 | 6 | 0 | 6 |
| SNRK | KIAA1211L | 0.719962 | 5 | 0 | 5 |
| SNRK | CAST | 0.718471 | 11 | 0 | 11 |
| SNRK | OSBPL10 | 0.714937 | 10 | 0 | 10 |
| SNRK | HIGD1A | 0.714567 | 13 | 0 | 12 |
| SNRK | FRMD6 | 0.714165 | 3 | 0 | 3 |
| SNRK | CALCOCO2 | 0.71289 | 11 | 0 | 11 |
| SNRK | HDHD2 | 0.711176 | 5 | 0 | 4 |
| SNRK | CUL2 | 0.711076 | 3 | 0 | 3 |
| SNRK | CYP27A1 | 0.7098 | 3 | 0 | 3 |
| SNRK | SNX14 | 0.709402 | 3 | 0 | 3 |
For details and further investigation, click here
