| Full name: kelch like family member 31 | Alias Symbol: bA345L23.2|BKLHD6 | ||
| Type: protein-coding gene | Cytoband: 6p12.1 | ||
| Entrez ID: 401265 | HGNC ID: HGNC:21353 | Ensembl Gene: ENSG00000124743 | OMIM ID: 610749 |
| Drug and gene relationship at DGIdb | |||
Expression of KLHL31:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | KLHL31 | 401265 | 234782_at | -0.0342 | 0.9133 | |
| GSE26886 | KLHL31 | 401265 | 234782_at | 0.4461 | 0.0015 | |
| GSE45670 | KLHL31 | 401265 | 234782_at | -0.0711 | 0.4882 | |
| GSE53622 | KLHL31 | 401265 | 68460 | 1.0112 | 0.0000 | |
| GSE53624 | KLHL31 | 401265 | 68460 | 1.2327 | 0.0000 | |
| GSE63941 | KLHL31 | 401265 | 239398_at | 0.5127 | 0.0467 | |
| GSE77861 | KLHL31 | 401265 | 239398_at | 0.0737 | 0.6551 | |
| GSE97050 | KLHL31 | 401265 | A_33_P3302881 | -0.1535 | 0.6885 | |
| SRP133303 | KLHL31 | 401265 | RNAseq | 0.5331 | 0.1541 | |
| SRP159526 | KLHL31 | 401265 | RNAseq | 1.1489 | 0.0130 | |
| SRP193095 | KLHL31 | 401265 | RNAseq | 0.8906 | 0.0002 | |
| SRP219564 | KLHL31 | 401265 | RNAseq | 1.3149 | 0.1348 | |
| TCGA | KLHL31 | 401265 | RNAseq | 0.2690 | 0.1942 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by KLHL31 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of KLHL31:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | KLHL31 | 401265 | 7 | 2 | 21 | |
| GSE20123 | KLHL31 | 401265 | 7 | 2 | 21 | |
| GSE43470 | KLHL31 | 401265 | 5 | 0 | 38 | |
| GSE46452 | KLHL31 | 401265 | 2 | 10 | 47 | |
| GSE47630 | KLHL31 | 401265 | 7 | 5 | 28 | |
| GSE54993 | KLHL31 | 401265 | 3 | 1 | 66 | |
| GSE54994 | KLHL31 | 401265 | 8 | 4 | 41 | |
| GSE60625 | KLHL31 | 401265 | 0 | 3 | 8 | |
| GSE74703 | KLHL31 | 401265 | 5 | 0 | 31 | |
| GSE74704 | KLHL31 | 401265 | 2 | 1 | 17 | |
| TCGA | KLHL31 | 401265 | 22 | 13 | 61 |
Total number of gains: 68; Total number of losses: 41; Total Number of normals: 379.
Somatic mutations of KLHL31:
Generating mutation plots.
Highly correlated genes for KLHL31:
Showing top 20/218 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| KLHL31 | SARDH | 0.78494 | 3 | 0 | 3 |
| KLHL31 | CTF1 | 0.780849 | 3 | 0 | 3 |
| KLHL31 | GPR135 | 0.774328 | 3 | 0 | 3 |
| KLHL31 | MRPL33 | 0.771251 | 3 | 0 | 3 |
| KLHL31 | CYTH3 | 0.76721 | 3 | 0 | 3 |
| KLHL31 | TPBG | 0.728666 | 3 | 0 | 3 |
| KLHL31 | SPIRE1 | 0.721617 | 3 | 0 | 3 |
| KLHL31 | FEZ1 | 0.719203 | 3 | 0 | 3 |
| KLHL31 | TCAP | 0.716216 | 3 | 0 | 3 |
| KLHL31 | CASKIN2 | 0.713664 | 3 | 0 | 3 |
| KLHL31 | PHC2 | 0.708952 | 3 | 0 | 3 |
| KLHL31 | PTGFRN | 0.708933 | 3 | 0 | 3 |
| KLHL31 | NPFFR1 | 0.707028 | 3 | 0 | 3 |
| KLHL31 | TBX18 | 0.70463 | 3 | 0 | 3 |
| KLHL31 | SDR39U1 | 0.698751 | 3 | 0 | 3 |
| KLHL31 | NFIL3 | 0.692684 | 3 | 0 | 3 |
| KLHL31 | DDX19A | 0.692277 | 4 | 0 | 4 |
| KLHL31 | PTP4A3 | 0.691215 | 3 | 0 | 3 |
| KLHL31 | FTO | 0.690769 | 3 | 0 | 3 |
| KLHL31 | UNC5A | 0.684321 | 3 | 0 | 3 |
For details and further investigation, click here
