| Full name: Dmx like 1 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 5q23.1 | ||
| Entrez ID: 1657 | HGNC ID: HGNC:2937 | Ensembl Gene: ENSG00000172869 | OMIM ID: 605671 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of DMXL1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DMXL1 | 1657 | 203791_at | -0.8400 | 0.0759 | |
| GSE20347 | DMXL1 | 1657 | 203791_at | -1.4407 | 0.0000 | |
| GSE23400 | DMXL1 | 1657 | 203791_at | -0.9798 | 0.0000 | |
| GSE26886 | DMXL1 | 1657 | 203791_at | -0.7771 | 0.0431 | |
| GSE29001 | DMXL1 | 1657 | 203791_at | -0.9839 | 0.0057 | |
| GSE38129 | DMXL1 | 1657 | 203791_at | -1.3168 | 0.0000 | |
| GSE45670 | DMXL1 | 1657 | 203791_at | -0.7363 | 0.0005 | |
| GSE53622 | DMXL1 | 1657 | 78347 | -1.3206 | 0.0000 | |
| GSE53624 | DMXL1 | 1657 | 142094 | -1.3189 | 0.0000 | |
| GSE63941 | DMXL1 | 1657 | 203791_at | -1.3979 | 0.0105 | |
| GSE77861 | DMXL1 | 1657 | 203791_at | -1.3582 | 0.0035 | |
| GSE97050 | DMXL1 | 1657 | A_23_P250571 | -0.9418 | 0.0781 | |
| SRP007169 | DMXL1 | 1657 | RNAseq | -0.9760 | 0.0055 | |
| SRP008496 | DMXL1 | 1657 | RNAseq | -0.9862 | 0.0000 | |
| SRP064894 | DMXL1 | 1657 | RNAseq | -0.9279 | 0.0006 | |
| SRP133303 | DMXL1 | 1657 | RNAseq | -0.6591 | 0.0000 | |
| SRP159526 | DMXL1 | 1657 | RNAseq | -1.0114 | 0.0214 | |
| SRP193095 | DMXL1 | 1657 | RNAseq | -1.0142 | 0.0000 | |
| SRP219564 | DMXL1 | 1657 | RNAseq | -0.9595 | 0.0367 | |
| TCGA | DMXL1 | 1657 | RNAseq | -0.3230 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 8.
Survival by DMXL1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DMXL1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DMXL1 | 1657 | 1 | 13 | 16 | |
| GSE20123 | DMXL1 | 1657 | 1 | 13 | 16 | |
| GSE43470 | DMXL1 | 1657 | 3 | 8 | 32 | |
| GSE46452 | DMXL1 | 1657 | 0 | 27 | 32 | |
| GSE47630 | DMXL1 | 1657 | 0 | 21 | 19 | |
| GSE54993 | DMXL1 | 1657 | 9 | 1 | 60 | |
| GSE54994 | DMXL1 | 1657 | 2 | 15 | 36 | |
| GSE60625 | DMXL1 | 1657 | 0 | 0 | 11 | |
| GSE74703 | DMXL1 | 1657 | 2 | 6 | 28 | |
| GSE74704 | DMXL1 | 1657 | 1 | 7 | 12 | |
| TCGA | DMXL1 | 1657 | 2 | 43 | 51 |
Total number of gains: 21; Total number of losses: 154; Total Number of normals: 313.
Somatic mutations of DMXL1:
Generating mutation plots.
Highly correlated genes for DMXL1:
Showing top 20/1664 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DMXL1 | CCDC7 | 0.787341 | 3 | 0 | 3 |
| DMXL1 | MRPS36 | 0.783491 | 8 | 0 | 7 |
| DMXL1 | CA13 | 0.774346 | 3 | 0 | 3 |
| DMXL1 | YTHDC2 | 0.772558 | 13 | 0 | 12 |
| DMXL1 | RAB5B | 0.770993 | 9 | 0 | 8 |
| DMXL1 | FCHO2 | 0.763052 | 9 | 0 | 9 |
| DMXL1 | SMIM14 | 0.75978 | 6 | 0 | 6 |
| DMXL1 | KAT2B | 0.758929 | 13 | 0 | 12 |
| DMXL1 | GPD1L | 0.758687 | 11 | 0 | 11 |
| DMXL1 | CPPED1 | 0.75856 | 11 | 0 | 10 |
| DMXL1 | CALCOCO2 | 0.75598 | 12 | 0 | 11 |
| DMXL1 | HSD17B4 | 0.755092 | 13 | 0 | 12 |
| DMXL1 | ARHGEF10L | 0.75218 | 10 | 0 | 9 |
| DMXL1 | FAM174A | 0.7512 | 8 | 0 | 7 |
| DMXL1 | CPEB4 | 0.744423 | 8 | 0 | 7 |
| DMXL1 | SLC10A5 | 0.741766 | 3 | 0 | 3 |
| DMXL1 | FBXO3 | 0.740948 | 11 | 0 | 10 |
| DMXL1 | FAM122A | 0.740904 | 4 | 0 | 4 |
| DMXL1 | CTTNBP2NL | 0.740539 | 7 | 0 | 7 |
| DMXL1 | UBL3 | 0.740532 | 11 | 0 | 10 |
For details and further investigation, click here
