CALCOCO2

 

Full name: calcium binding and coiled-coil domain 2 Alias Symbol: MGC17318|NDP52
Type: protein-coding gene Cytoband: 17q21.32
Entrez ID: 10241 HGNC ID: HGNC:29912 Ensembl Gene: ENSG00000136436 OMIM ID: 604587
Drug and gene relationship at DGIdb

 

Expression of CALCOCO2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 CALCOCO2 10241 210817_s_at -0.8340 0.0086
GSE20347 CALCOCO2 10241 210817_s_at -1.1608 0.0000
GSE23400 CALCOCO2 10241 210817_s_at -0.4712 0.0000
GSE26886 CALCOCO2 10241 210817_s_at -1.5515 0.0000
GSE29001 CALCOCO2 10241 210817_s_at -0.8213 0.0003
GSE38129 CALCOCO2 10241 210817_s_at -0.9936 0.0000
GSE45670 CALCOCO2 10241 210817_s_at -0.6414 0.0001
GSE53622 CALCOCO2 10241 76116 -0.9613 0.0000
GSE53624 CALCOCO2 10241 76116 -0.7815 0.0000
GSE63941 CALCOCO2 10241 210817_s_at -0.1847 0.6790
GSE77861 CALCOCO2 10241 210817_s_at -0.9198 0.0136
GSE97050 CALCOCO2 10241 A_24_P330773 -1.0622 0.0555
SRP007169 CALCOCO2 10241 RNAseq -1.5949 0.0000
SRP008496 CALCOCO2 10241 RNAseq -1.5811 0.0000
SRP064894 CALCOCO2 10241 RNAseq -0.4918 0.0009
SRP133303 CALCOCO2 10241 RNAseq -0.6281 0.0013
SRP159526 CALCOCO2 10241 RNAseq -0.6161 0.0091
SRP193095 CALCOCO2 10241 RNAseq -0.8093 0.0000
SRP219564 CALCOCO2 10241 RNAseq -0.1716 0.4268
TCGA CALCOCO2 10241 RNAseq -0.1571 0.0003

Upregulated datasets: 0; Downregulated datasets: 4.  


 

Survival by CALCOCO2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of CALCOCO2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 CALCOCO2 10241 6 2 22
GSE20123 CALCOCO2 10241 6 2 22
GSE43470 CALCOCO2 10241 3 1 39
GSE46452 CALCOCO2 10241 32 0 27
GSE47630 CALCOCO2 10241 9 0 31
GSE54993 CALCOCO2 10241 2 4 64
GSE54994 CALCOCO2 10241 10 6 37
GSE60625 CALCOCO2 10241 4 0 7
GSE74703 CALCOCO2 10241 3 1 32
GSE74704 CALCOCO2 10241 4 1 15
TCGA CALCOCO2 10241 27 6 63

Total number of gains: 106; Total number of losses: 23; Total Number of normals: 359.  


 

Somatic mutations of CALCOCO2:

 

Generating mutation plots.

 

Highly correlated genes for CALCOCO2:

 

Showing top 20/1967 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
CALCOCO2EIF4E30.799312808
CALCOCO2COPZ10.789058303
CALCOCO2PREX20.787798404
CALCOCO2SNORA680.784444404
CALCOCO2RAP1A0.77216411011
CALCOCO2CLEC3B0.76884303
CALCOCO2KAT2B0.76568912011
CALCOCO2CAB39L0.76469311011
CALCOCO2GPRASP20.763683303
CALCOCO2KDM5D0.763336303
CALCOCO2AK90.759615606
CALCOCO2HPGD0.75859811011
CALCOCO2HDHD20.758493505
CALCOCO2DMXL10.7559812011
CALCOCO2CPEB30.75538310010
CALCOCO2MSRA0.75364311011
CALCOCO2STX120.75221611011
CALCOCO2AK30.752086707
CALCOCO2SECISBP2L0.75132111011
CALCOCO2PINK10.748449909

For details and further investigation, click here