| Full name: mortality factor 4 like 1 | Alias Symbol: MRG15|MORFRG15|HsT17725|Eaf3|MEAF3 | ||
| Type: protein-coding gene | Cytoband: 15q25.1 | ||
| Entrez ID: 10933 | HGNC ID: HGNC:16989 | Ensembl Gene: ENSG00000185787 | OMIM ID: 607303 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of MORF4L1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MORF4L1 | 10933 | 217982_s_at | 0.0157 | 0.9822 | |
| GSE20347 | MORF4L1 | 10933 | 217982_s_at | 0.4454 | 0.0018 | |
| GSE23400 | MORF4L1 | 10933 | 217982_s_at | 0.3376 | 0.0000 | |
| GSE26886 | MORF4L1 | 10933 | 217982_s_at | -0.1637 | 0.2067 | |
| GSE29001 | MORF4L1 | 10933 | 217982_s_at | 0.2838 | 0.1632 | |
| GSE38129 | MORF4L1 | 10933 | 217982_s_at | 0.2809 | 0.0306 | |
| GSE45670 | MORF4L1 | 10933 | 217982_s_at | -0.0489 | 0.6591 | |
| GSE53622 | MORF4L1 | 10933 | 91130 | 0.3315 | 0.0000 | |
| GSE53624 | MORF4L1 | 10933 | 91130 | 0.3862 | 0.0000 | |
| GSE63941 | MORF4L1 | 10933 | 217982_s_at | -0.2564 | 0.2003 | |
| GSE77861 | MORF4L1 | 10933 | 217982_s_at | 0.2458 | 0.2159 | |
| GSE97050 | MORF4L1 | 10933 | A_24_P398898 | -0.1490 | 0.4768 | |
| SRP007169 | MORF4L1 | 10933 | RNAseq | 0.0376 | 0.9087 | |
| SRP008496 | MORF4L1 | 10933 | RNAseq | 0.2070 | 0.1718 | |
| SRP064894 | MORF4L1 | 10933 | RNAseq | 0.3394 | 0.0236 | |
| SRP133303 | MORF4L1 | 10933 | RNAseq | 0.4976 | 0.0045 | |
| SRP159526 | MORF4L1 | 10933 | RNAseq | 0.3220 | 0.1027 | |
| SRP193095 | MORF4L1 | 10933 | RNAseq | 0.3616 | 0.0008 | |
| SRP219564 | MORF4L1 | 10933 | RNAseq | 0.0339 | 0.9328 | |
| TCGA | MORF4L1 | 10933 | RNAseq | 0.0572 | 0.2142 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MORF4L1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MORF4L1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MORF4L1 | 10933 | 7 | 1 | 22 | |
| GSE20123 | MORF4L1 | 10933 | 7 | 1 | 22 | |
| GSE43470 | MORF4L1 | 10933 | 4 | 5 | 34 | |
| GSE46452 | MORF4L1 | 10933 | 3 | 7 | 49 | |
| GSE47630 | MORF4L1 | 10933 | 8 | 10 | 22 | |
| GSE54993 | MORF4L1 | 10933 | 5 | 6 | 59 | |
| GSE54994 | MORF4L1 | 10933 | 5 | 6 | 42 | |
| GSE60625 | MORF4L1 | 10933 | 4 | 0 | 7 | |
| GSE74703 | MORF4L1 | 10933 | 4 | 3 | 29 | |
| GSE74704 | MORF4L1 | 10933 | 3 | 1 | 16 | |
| TCGA | MORF4L1 | 10933 | 14 | 15 | 67 |
Total number of gains: 64; Total number of losses: 55; Total Number of normals: 369.
Somatic mutations of MORF4L1:
Generating mutation plots.
Highly correlated genes for MORF4L1:
Showing top 20/983 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MORF4L1 | CLEC2B | 0.750448 | 3 | 0 | 3 |
| MORF4L1 | RAB34 | 0.744909 | 3 | 0 | 3 |
| MORF4L1 | RCN2 | 0.742041 | 9 | 0 | 9 |
| MORF4L1 | FADS1 | 0.727938 | 3 | 0 | 3 |
| MORF4L1 | CLP1 | 0.718856 | 3 | 0 | 3 |
| MORF4L1 | ATL1 | 0.69973 | 3 | 0 | 3 |
| MORF4L1 | RPS16 | 0.698423 | 4 | 0 | 4 |
| MORF4L1 | ZDHHC4 | 0.689783 | 8 | 0 | 6 |
| MORF4L1 | TM2D3 | 0.689759 | 11 | 0 | 10 |
| MORF4L1 | CDC14B | 0.688968 | 3 | 0 | 3 |
| MORF4L1 | DNAJC8 | 0.686936 | 6 | 0 | 5 |
| MORF4L1 | ZMYM6 | 0.683796 | 9 | 0 | 7 |
| MORF4L1 | CDK14 | 0.677911 | 8 | 0 | 7 |
| MORF4L1 | VPS13C | 0.677512 | 9 | 0 | 8 |
| MORF4L1 | C12orf57 | 0.677471 | 6 | 0 | 6 |
| MORF4L1 | AIMP2 | 0.675496 | 4 | 0 | 4 |
| MORF4L1 | RNF26 | 0.673906 | 3 | 0 | 3 |
| MORF4L1 | PIAS2 | 0.672567 | 4 | 0 | 3 |
| MORF4L1 | VKORC1 | 0.672153 | 10 | 0 | 8 |
| MORF4L1 | DCTD | 0.669835 | 3 | 0 | 3 |
For details and further investigation, click here
