| Full name: F-box protein 44 | Alias Symbol: FBX30|FBG3|MGC14140|Fbxo6a|Fbx44 | ||
| Type: protein-coding gene | Cytoband: 1p36.22 | ||
| Entrez ID: 93611 | HGNC ID: HGNC:24847 | Ensembl Gene: ENSG00000132879 | OMIM ID: 609111 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
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Expression of FBXO44:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FBXO44 | 93611 | 223517_at | 0.3558 | 0.2712 | |
| GSE26886 | FBXO44 | 93611 | 223517_at | 0.5209 | 0.0006 | |
| GSE45670 | FBXO44 | 93611 | 223517_at | -0.0050 | 0.9679 | |
| GSE53622 | FBXO44 | 93611 | 50273 | 0.2313 | 0.0001 | |
| GSE53624 | FBXO44 | 93611 | 50273 | -0.0656 | 0.3662 | |
| GSE63941 | FBXO44 | 93611 | 223517_at | 0.3337 | 0.1679 | |
| GSE77861 | FBXO44 | 93611 | 223517_at | 0.0253 | 0.9146 | |
| GSE97050 | FBXO44 | 93611 | A_23_P200637 | -0.2690 | 0.2826 | |
| SRP007169 | FBXO44 | 93611 | RNAseq | 0.2223 | 0.6785 | |
| SRP008496 | FBXO44 | 93611 | RNAseq | 0.8302 | 0.0448 | |
| SRP064894 | FBXO44 | 93611 | RNAseq | 0.2453 | 0.2916 | |
| SRP133303 | FBXO44 | 93611 | RNAseq | -0.2311 | 0.1744 | |
| SRP159526 | FBXO44 | 93611 | RNAseq | 0.4974 | 0.3328 | |
| SRP193095 | FBXO44 | 93611 | RNAseq | 0.4248 | 0.0008 | |
| SRP219564 | FBXO44 | 93611 | RNAseq | 0.0450 | 0.9179 | |
| TCGA | FBXO44 | 93611 | RNAseq | 0.0381 | 0.6008 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by FBXO44 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FBXO44:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FBXO44 | 93611 | 0 | 5 | 25 | |
| GSE20123 | FBXO44 | 93611 | 0 | 4 | 26 | |
| GSE43470 | FBXO44 | 93611 | 5 | 5 | 33 | |
| GSE46452 | FBXO44 | 93611 | 7 | 1 | 51 | |
| GSE47630 | FBXO44 | 93611 | 8 | 4 | 28 | |
| GSE54993 | FBXO44 | 93611 | 3 | 1 | 66 | |
| GSE54994 | FBXO44 | 93611 | 11 | 4 | 38 | |
| GSE60625 | FBXO44 | 93611 | 0 | 0 | 11 | |
| GSE74703 | FBXO44 | 93611 | 4 | 3 | 29 | |
| GSE74704 | FBXO44 | 93611 | 0 | 0 | 20 | |
| TCGA | FBXO44 | 93611 | 10 | 23 | 63 |
Total number of gains: 48; Total number of losses: 50; Total Number of normals: 390.
Somatic mutations of FBXO44:
Generating mutation plots.
Highly correlated genes for FBXO44:
Showing top 20/392 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FBXO44 | DNLZ | 0.801046 | 3 | 0 | 3 |
| FBXO44 | CBS | 0.759019 | 3 | 0 | 3 |
| FBXO44 | CLDN14 | 0.737971 | 3 | 0 | 3 |
| FBXO44 | DOHH | 0.725718 | 4 | 0 | 4 |
| FBXO44 | GTF2IRD2 | 0.725159 | 3 | 0 | 3 |
| FBXO44 | DRGX | 0.714141 | 3 | 0 | 3 |
| FBXO44 | IL17B | 0.712521 | 3 | 0 | 3 |
| FBXO44 | DNMT3B | 0.70679 | 3 | 0 | 3 |
| FBXO44 | FOXD3-AS1 | 0.701992 | 3 | 0 | 3 |
| FBXO44 | HSPBAP1 | 0.69915 | 3 | 0 | 3 |
| FBXO44 | SHARPIN | 0.697894 | 4 | 0 | 4 |
| FBXO44 | GPR26 | 0.691108 | 3 | 0 | 3 |
| FBXO44 | LONP1 | 0.688727 | 3 | 0 | 3 |
| FBXO44 | RHEBL1 | 0.688249 | 3 | 0 | 3 |
| FBXO44 | MUC2 | 0.686189 | 3 | 0 | 3 |
| FBXO44 | C9orf106 | 0.684963 | 3 | 0 | 3 |
| FBXO44 | MAG | 0.684502 | 4 | 0 | 4 |
| FBXO44 | DMGDH | 0.682311 | 3 | 0 | 3 |
| FBXO44 | OSBPL5 | 0.680675 | 4 | 0 | 4 |
| FBXO44 | TFR2 | 0.679834 | 3 | 0 | 3 |
For details and further investigation, click here
