| Full name: DTW domain containing 1 | Alias Symbol: MDS009|MGC111207 | ||
| Type: protein-coding gene | Cytoband: 15q21.2 | ||
| Entrez ID: 56986 | HGNC ID: HGNC:30926 | Ensembl Gene: ENSG00000104047 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of DTWD1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DTWD1 | 56986 | 219291_at | -0.5163 | 0.2674 | |
| GSE20347 | DTWD1 | 56986 | 219291_at | 0.0929 | 0.5425 | |
| GSE23400 | DTWD1 | 56986 | 219291_at | -0.0307 | 0.4967 | |
| GSE26886 | DTWD1 | 56986 | 229984_at | -0.4321 | 0.0503 | |
| GSE29001 | DTWD1 | 56986 | 219291_at | -0.0037 | 0.9890 | |
| GSE38129 | DTWD1 | 56986 | 219291_at | -0.0314 | 0.8387 | |
| GSE45670 | DTWD1 | 56986 | 219291_at | -0.5270 | 0.0007 | |
| GSE53622 | DTWD1 | 56986 | 37801 | -0.1541 | 0.0845 | |
| GSE53624 | DTWD1 | 56986 | 39332 | -0.0069 | 0.9433 | |
| GSE63941 | DTWD1 | 56986 | 219291_at | -1.7657 | 0.0001 | |
| GSE77861 | DTWD1 | 56986 | 219291_at | -0.0520 | 0.8553 | |
| GSE97050 | DTWD1 | 56986 | A_24_P70117 | -0.3070 | 0.2544 | |
| SRP007169 | DTWD1 | 56986 | RNAseq | 0.1643 | 0.6829 | |
| SRP008496 | DTWD1 | 56986 | RNAseq | 0.1959 | 0.4532 | |
| SRP064894 | DTWD1 | 56986 | RNAseq | -0.0574 | 0.7323 | |
| SRP133303 | DTWD1 | 56986 | RNAseq | -0.2895 | 0.0413 | |
| SRP159526 | DTWD1 | 56986 | RNAseq | -0.3081 | 0.0930 | |
| SRP193095 | DTWD1 | 56986 | RNAseq | -0.1936 | 0.0937 | |
| SRP219564 | DTWD1 | 56986 | RNAseq | -0.2875 | 0.5335 | |
| TCGA | DTWD1 | 56986 | RNAseq | -0.2348 | 0.0001 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by DTWD1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DTWD1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DTWD1 | 56986 | 5 | 3 | 22 | |
| GSE20123 | DTWD1 | 56986 | 5 | 3 | 22 | |
| GSE43470 | DTWD1 | 56986 | 5 | 4 | 34 | |
| GSE46452 | DTWD1 | 56986 | 3 | 7 | 49 | |
| GSE47630 | DTWD1 | 56986 | 8 | 10 | 22 | |
| GSE54993 | DTWD1 | 56986 | 4 | 6 | 60 | |
| GSE54994 | DTWD1 | 56986 | 5 | 7 | 41 | |
| GSE60625 | DTWD1 | 56986 | 4 | 0 | 7 | |
| GSE74703 | DTWD1 | 56986 | 5 | 3 | 28 | |
| GSE74704 | DTWD1 | 56986 | 2 | 3 | 15 | |
| TCGA | DTWD1 | 56986 | 9 | 16 | 71 |
Total number of gains: 55; Total number of losses: 62; Total Number of normals: 371.
Somatic mutations of DTWD1:
Generating mutation plots.
Highly correlated genes for DTWD1:
Showing top 20/741 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DTWD1 | LRIG3 | 0.799245 | 3 | 0 | 3 |
| DTWD1 | TK2 | 0.795161 | 3 | 0 | 3 |
| DTWD1 | PINK1 | 0.788037 | 3 | 0 | 3 |
| DTWD1 | RNF185 | 0.758254 | 3 | 0 | 3 |
| DTWD1 | PARD3B | 0.757961 | 4 | 0 | 4 |
| DTWD1 | HEATR5B | 0.749122 | 3 | 0 | 3 |
| DTWD1 | VPS36 | 0.739064 | 3 | 0 | 3 |
| DTWD1 | PIAS2 | 0.729393 | 3 | 0 | 3 |
| DTWD1 | FIBIN | 0.726301 | 4 | 0 | 4 |
| DTWD1 | PJA1 | 0.723886 | 3 | 0 | 3 |
| DTWD1 | ECD | 0.723612 | 4 | 0 | 3 |
| DTWD1 | SARNP | 0.721282 | 3 | 0 | 3 |
| DTWD1 | MRPS35 | 0.719663 | 4 | 0 | 4 |
| DTWD1 | ZNF791 | 0.717467 | 3 | 0 | 3 |
| DTWD1 | APPL1 | 0.714695 | 4 | 0 | 4 |
| DTWD1 | HAUS6 | 0.713287 | 3 | 0 | 3 |
| DTWD1 | ANKRD50 | 0.711122 | 3 | 0 | 3 |
| DTWD1 | ZNF844 | 0.707358 | 4 | 0 | 3 |
| DTWD1 | ADAM9 | 0.705058 | 3 | 0 | 3 |
| DTWD1 | CRYL1 | 0.702318 | 4 | 0 | 3 |
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