| Full name: ADAM metallopeptidase domain 9 | Alias Symbol: MDC9|KIAA0021|MCMP|Mltng | ||
| Type: protein-coding gene | Cytoband: 8p11.22 | ||
| Entrez ID: 8754 | HGNC ID: HGNC:216 | Ensembl Gene: ENSG00000168615 | OMIM ID: 602713 |
| Drug and gene relationship at DGIdb | |||
Expression of ADAM9:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ADAM9 | 8754 | 202381_at | 0.2527 | 0.7103 | |
| GSE20347 | ADAM9 | 8754 | 202381_at | 0.5592 | 0.0182 | |
| GSE23400 | ADAM9 | 8754 | 202381_at | 0.2045 | 0.1792 | |
| GSE26886 | ADAM9 | 8754 | 202381_at | -0.6630 | 0.0427 | |
| GSE29001 | ADAM9 | 8754 | 202381_at | -0.1537 | 0.8410 | |
| GSE38129 | ADAM9 | 8754 | 202381_at | 0.4971 | 0.0065 | |
| GSE45670 | ADAM9 | 8754 | 202381_at | 0.4471 | 0.0258 | |
| GSE63941 | ADAM9 | 8754 | 202381_at | -1.7605 | 0.0018 | |
| GSE77861 | ADAM9 | 8754 | 202381_at | 0.5025 | 0.2560 | |
| GSE97050 | ADAM9 | 8754 | A_33_P3340769 | 0.2613 | 0.4077 | |
| SRP007169 | ADAM9 | 8754 | RNAseq | 0.7585 | 0.0916 | |
| SRP008496 | ADAM9 | 8754 | RNAseq | 0.5832 | 0.0546 | |
| SRP064894 | ADAM9 | 8754 | RNAseq | -0.1452 | 0.6476 | |
| SRP133303 | ADAM9 | 8754 | RNAseq | 1.1543 | 0.0000 | |
| SRP159526 | ADAM9 | 8754 | RNAseq | 0.1337 | 0.7941 | |
| SRP193095 | ADAM9 | 8754 | RNAseq | 0.2868 | 0.1654 | |
| SRP219564 | ADAM9 | 8754 | RNAseq | -0.0179 | 0.9762 | |
| TCGA | ADAM9 | 8754 | RNAseq | -0.1166 | 0.0608 |
Upregulated datasets: 1; Downregulated datasets: 1.
Survival by ADAM9 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of ADAM9:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ADAM9 | 8754 | 10 | 4 | 16 | |
| GSE20123 | ADAM9 | 8754 | 10 | 4 | 16 | |
| GSE43470 | ADAM9 | 8754 | 8 | 6 | 29 | |
| GSE46452 | ADAM9 | 8754 | 20 | 5 | 34 | |
| GSE47630 | ADAM9 | 8754 | 12 | 7 | 21 | |
| GSE54993 | ADAM9 | 8754 | 2 | 16 | 52 | |
| GSE54994 | ADAM9 | 8754 | 17 | 7 | 29 | |
| GSE60625 | ADAM9 | 8754 | 3 | 0 | 8 | |
| GSE74703 | ADAM9 | 8754 | 8 | 5 | 23 | |
| GSE74704 | ADAM9 | 8754 | 9 | 1 | 10 | |
| TCGA | ADAM9 | 8754 | 36 | 23 | 37 |
Total number of gains: 135; Total number of losses: 78; Total Number of normals: 275.
Somatic mutations of ADAM9:
Generating mutation plots.
Highly correlated genes for ADAM9:
Showing top 20/444 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ADAM9 | SLC35E3 | 0.845016 | 3 | 0 | 3 |
| ADAM9 | TMEM60 | 0.791466 | 3 | 0 | 3 |
| ADAM9 | ZNF319 | 0.770908 | 3 | 0 | 3 |
| ADAM9 | SDHB | 0.764544 | 3 | 0 | 3 |
| ADAM9 | TM2D2 | 0.734619 | 6 | 0 | 6 |
| ADAM9 | KDSR | 0.734161 | 3 | 0 | 3 |
| ADAM9 | MAPK9 | 0.732268 | 3 | 0 | 3 |
| ADAM9 | MRPL44 | 0.730607 | 3 | 0 | 3 |
| ADAM9 | GMCL1 | 0.727432 | 3 | 0 | 3 |
| ADAM9 | AFAP1 | 0.725848 | 3 | 0 | 3 |
| ADAM9 | LACTB | 0.725827 | 4 | 0 | 4 |
| ADAM9 | FASTKD2 | 0.725204 | 3 | 0 | 3 |
| ADAM9 | MTFMT | 0.724636 | 3 | 0 | 3 |
| ADAM9 | FZD1 | 0.718313 | 3 | 0 | 3 |
| ADAM9 | VPS13C | 0.717878 | 3 | 0 | 3 |
| ADAM9 | GIN1 | 0.715281 | 3 | 0 | 3 |
| ADAM9 | CSNK2A2 | 0.71101 | 3 | 0 | 3 |
| ADAM9 | ZBED6 | 0.710126 | 3 | 0 | 3 |
| ADAM9 | SPRED2 | 0.709599 | 3 | 0 | 3 |
| ADAM9 | BMPR2 | 0.70741 | 3 | 0 | 3 |
For details and further investigation, click here
