| Full name: HEAT repeat containing 5B | Alias Symbol: KIAA1414|DKFZp686P15184 | ||
| Type: protein-coding gene | Cytoband: 2p22.2 | ||
| Entrez ID: 54497 | HGNC ID: HGNC:29273 | Ensembl Gene: ENSG00000008869 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of HEATR5B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | HEATR5B | 54497 | 233642_s_at | -0.1426 | 0.6479 | |
| GSE26886 | HEATR5B | 54497 | 233642_s_at | -0.3685 | 0.0225 | |
| GSE45670 | HEATR5B | 54497 | 233642_s_at | -0.1665 | 0.1942 | |
| GSE53622 | HEATR5B | 54497 | 15294 | -0.5435 | 0.0000 | |
| GSE53624 | HEATR5B | 54497 | 15294 | -0.6105 | 0.0000 | |
| GSE63941 | HEATR5B | 54497 | 233642_s_at | -0.5219 | 0.4222 | |
| GSE77861 | HEATR5B | 54497 | 233642_s_at | -0.2594 | 0.1710 | |
| GSE97050 | HEATR5B | 54497 | A_32_P389118 | -0.4856 | 0.2358 | |
| SRP007169 | HEATR5B | 54497 | RNAseq | -0.2988 | 0.3981 | |
| SRP008496 | HEATR5B | 54497 | RNAseq | -0.2505 | 0.1925 | |
| SRP064894 | HEATR5B | 54497 | RNAseq | -0.4248 | 0.0994 | |
| SRP133303 | HEATR5B | 54497 | RNAseq | -0.3799 | 0.0001 | |
| SRP159526 | HEATR5B | 54497 | RNAseq | -0.4047 | 0.0853 | |
| SRP193095 | HEATR5B | 54497 | RNAseq | -0.4242 | 0.0001 | |
| SRP219564 | HEATR5B | 54497 | RNAseq | -0.4588 | 0.2963 | |
| TCGA | HEATR5B | 54497 | RNAseq | -0.1318 | 0.0051 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by HEATR5B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of HEATR5B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | HEATR5B | 54497 | 10 | 1 | 19 | |
| GSE20123 | HEATR5B | 54497 | 9 | 1 | 20 | |
| GSE43470 | HEATR5B | 54497 | 3 | 0 | 40 | |
| GSE46452 | HEATR5B | 54497 | 1 | 4 | 54 | |
| GSE47630 | HEATR5B | 54497 | 7 | 0 | 33 | |
| GSE54993 | HEATR5B | 54497 | 0 | 5 | 65 | |
| GSE54994 | HEATR5B | 54497 | 10 | 0 | 43 | |
| GSE60625 | HEATR5B | 54497 | 0 | 3 | 8 | |
| GSE74703 | HEATR5B | 54497 | 3 | 0 | 33 | |
| GSE74704 | HEATR5B | 54497 | 9 | 1 | 10 | |
| TCGA | HEATR5B | 54497 | 35 | 2 | 59 |
Total number of gains: 87; Total number of losses: 17; Total Number of normals: 384.
Somatic mutations of HEATR5B:
Generating mutation plots.
Highly correlated genes for HEATR5B:
Showing top 20/1076 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| HEATR5B | CA13 | 0.773394 | 3 | 0 | 3 |
| HEATR5B | LYRM7 | 0.768024 | 3 | 0 | 3 |
| HEATR5B | NPAS2 | 0.767051 | 4 | 0 | 4 |
| HEATR5B | C2CD2 | 0.765728 | 3 | 0 | 3 |
| HEATR5B | PLEKHF2 | 0.75755 | 3 | 0 | 3 |
| HEATR5B | TXLNG | 0.751203 | 3 | 0 | 3 |
| HEATR5B | MARK2 | 0.749888 | 3 | 0 | 3 |
| HEATR5B | DTWD1 | 0.749122 | 3 | 0 | 3 |
| HEATR5B | SLC10A5 | 0.747552 | 3 | 0 | 3 |
| HEATR5B | TBK1 | 0.745516 | 4 | 0 | 4 |
| HEATR5B | CASP4 | 0.743888 | 3 | 0 | 3 |
| HEATR5B | SLC12A6 | 0.739649 | 5 | 0 | 5 |
| HEATR5B | SLC35A3 | 0.738957 | 3 | 0 | 3 |
| HEATR5B | FBXW2 | 0.737225 | 3 | 0 | 3 |
| HEATR5B | SLC22A15 | 0.731106 | 3 | 0 | 3 |
| HEATR5B | CRBN | 0.728157 | 3 | 0 | 3 |
| HEATR5B | EBPL | 0.727856 | 4 | 0 | 4 |
| HEATR5B | DIS3L | 0.716128 | 3 | 0 | 3 |
| HEATR5B | VDAC2 | 0.709856 | 3 | 0 | 3 |
| HEATR5B | HMGN3 | 0.708229 | 3 | 0 | 3 |
For details and further investigation, click here
