| Full name: dual specificity phosphatase 28 | Alias Symbol: VHP|DUSP26 | ||
| Type: protein-coding gene | Cytoband: 2q37.3 | ||
| Entrez ID: 285193 | HGNC ID: HGNC:33237 | Ensembl Gene: ENSG00000188542 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of DUSP28:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DUSP28 | 285193 | 229211_at | -0.2615 | 0.6758 | |
| GSE26886 | DUSP28 | 285193 | 229211_at | -0.5535 | 0.0863 | |
| GSE45670 | DUSP28 | 285193 | 229211_at | -0.0414 | 0.8467 | |
| GSE53622 | DUSP28 | 285193 | 59003 | -0.1447 | 0.0156 | |
| GSE53624 | DUSP28 | 285193 | 59003 | -0.1297 | 0.0778 | |
| GSE63941 | DUSP28 | 285193 | 229211_at | 0.1266 | 0.8211 | |
| GSE77861 | DUSP28 | 285193 | 229211_at | -0.1537 | 0.3881 | |
| GSE97050 | DUSP28 | 285193 | A_33_P3383656 | -0.0708 | 0.8223 | |
| SRP007169 | DUSP28 | 285193 | RNAseq | 0.1897 | 0.7420 | |
| SRP008496 | DUSP28 | 285193 | RNAseq | -0.4477 | 0.2993 | |
| SRP064894 | DUSP28 | 285193 | RNAseq | -0.0713 | 0.7237 | |
| SRP133303 | DUSP28 | 285193 | RNAseq | -0.2151 | 0.0811 | |
| SRP159526 | DUSP28 | 285193 | RNAseq | -0.1157 | 0.6777 | |
| SRP193095 | DUSP28 | 285193 | RNAseq | -0.3104 | 0.0034 | |
| SRP219564 | DUSP28 | 285193 | RNAseq | 0.1373 | 0.6904 | |
| TCGA | DUSP28 | 285193 | RNAseq | -0.1163 | 0.1462 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DUSP28 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DUSP28:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DUSP28 | 285193 | 1 | 12 | 17 | |
| GSE20123 | DUSP28 | 285193 | 1 | 12 | 17 | |
| GSE43470 | DUSP28 | 285193 | 1 | 9 | 33 | |
| GSE46452 | DUSP28 | 285193 | 0 | 5 | 54 | |
| GSE47630 | DUSP28 | 285193 | 4 | 5 | 31 | |
| GSE54993 | DUSP28 | 285193 | 3 | 3 | 64 | |
| GSE54994 | DUSP28 | 285193 | 8 | 9 | 36 | |
| GSE60625 | DUSP28 | 285193 | 0 | 3 | 8 | |
| GSE74703 | DUSP28 | 285193 | 1 | 7 | 28 | |
| GSE74704 | DUSP28 | 285193 | 1 | 5 | 14 | |
| TCGA | DUSP28 | 285193 | 11 | 29 | 56 |
Total number of gains: 31; Total number of losses: 99; Total Number of normals: 358.
Somatic mutations of DUSP28:
Generating mutation plots.
Highly correlated genes for DUSP28:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DUSP28 | BTRC | 0.705797 | 3 | 0 | 3 |
| DUSP28 | RAC1 | 0.703342 | 3 | 0 | 3 |
| DUSP28 | ZNF395 | 0.700847 | 3 | 0 | 3 |
| DUSP28 | UGP2 | 0.699193 | 3 | 0 | 3 |
| DUSP28 | FYCO1 | 0.681218 | 3 | 0 | 3 |
| DUSP28 | BTBD7 | 0.680422 | 3 | 0 | 3 |
| DUSP28 | WASF2 | 0.660868 | 3 | 0 | 3 |
| DUSP28 | PTRHD1 | 0.659088 | 3 | 0 | 3 |
| DUSP28 | FRS2 | 0.65504 | 3 | 0 | 3 |
| DUSP28 | SYPL1 | 0.649211 | 3 | 0 | 3 |
| DUSP28 | ZNF564 | 0.647902 | 3 | 0 | 3 |
| DUSP28 | EXOC6B | 0.646872 | 3 | 0 | 3 |
| DUSP28 | PCBD2 | 0.644614 | 4 | 0 | 3 |
| DUSP28 | SLC16A14 | 0.643498 | 4 | 0 | 3 |
| DUSP28 | IREB2 | 0.641436 | 3 | 0 | 3 |
| DUSP28 | HDDC3 | 0.640219 | 3 | 0 | 3 |
| DUSP28 | ARHGAP5-AS1 | 0.638539 | 4 | 0 | 3 |
| DUSP28 | PITPNM3 | 0.637883 | 4 | 0 | 3 |
| DUSP28 | TMEM19 | 0.637553 | 3 | 0 | 3 |
| DUSP28 | EPHA4 | 0.636893 | 3 | 0 | 3 |
For details and further investigation, click here
