| Full name: pterin-4 alpha-carbinolamine dehydratase 2 | Alias Symbol: DCOHM|DCOH2 | ||
| Type: protein-coding gene | Cytoband: 5q31.1 | ||
| Entrez ID: 84105 | HGNC ID: HGNC:24474 | Ensembl Gene: ENSG00000132570 | OMIM ID: 609836 |
| Drug and gene relationship at DGIdb | |||
Expression of PCBD2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PCBD2 | 84105 | 223712_at | -0.5560 | 0.1391 | |
| GSE26886 | PCBD2 | 84105 | 223712_at | -0.3381 | 0.3868 | |
| GSE45670 | PCBD2 | 84105 | 223712_at | -0.4381 | 0.0812 | |
| GSE53622 | PCBD2 | 84105 | 70405 | -0.4504 | 0.0000 | |
| GSE53624 | PCBD2 | 84105 | 70405 | -0.4608 | 0.0000 | |
| GSE63941 | PCBD2 | 84105 | 1554894_a_at | 0.8717 | 0.1336 | |
| GSE77861 | PCBD2 | 84105 | 1554894_a_at | -0.5881 | 0.0325 | |
| GSE97050 | PCBD2 | 84105 | A_33_P3661631 | 0.0637 | 0.7683 | |
| SRP007169 | PCBD2 | 84105 | RNAseq | -0.8961 | 0.0290 | |
| SRP008496 | PCBD2 | 84105 | RNAseq | -0.9055 | 0.0017 | |
| SRP064894 | PCBD2 | 84105 | RNAseq | -0.5432 | 0.0007 | |
| SRP133303 | PCBD2 | 84105 | RNAseq | -0.2020 | 0.1270 | |
| SRP159526 | PCBD2 | 84105 | RNAseq | -0.3208 | 0.3898 | |
| SRP193095 | PCBD2 | 84105 | RNAseq | -0.3390 | 0.0028 | |
| SRP219564 | PCBD2 | 84105 | RNAseq | -0.4230 | 0.1520 | |
| TCGA | PCBD2 | 84105 | RNAseq | -0.4086 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PCBD2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PCBD2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PCBD2 | 84105 | 3 | 11 | 16 | |
| GSE20123 | PCBD2 | 84105 | 4 | 11 | 15 | |
| GSE43470 | PCBD2 | 84105 | 4 | 6 | 33 | |
| GSE46452 | PCBD2 | 84105 | 0 | 27 | 32 | |
| GSE47630 | PCBD2 | 84105 | 0 | 21 | 19 | |
| GSE54993 | PCBD2 | 84105 | 9 | 1 | 60 | |
| GSE54994 | PCBD2 | 84105 | 3 | 13 | 37 | |
| GSE60625 | PCBD2 | 84105 | 0 | 0 | 11 | |
| GSE74703 | PCBD2 | 84105 | 3 | 4 | 29 | |
| GSE74704 | PCBD2 | 84105 | 3 | 5 | 12 | |
| TCGA | PCBD2 | 84105 | 3 | 36 | 57 |
Total number of gains: 32; Total number of losses: 135; Total Number of normals: 321.
Somatic mutations of PCBD2:
Generating mutation plots.
Highly correlated genes for PCBD2:
Showing top 20/670 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PCBD2 | CD59 | 0.796926 | 3 | 0 | 3 |
| PCBD2 | UGP2 | 0.769198 | 4 | 0 | 4 |
| PCBD2 | MRPS10 | 0.765979 | 3 | 0 | 3 |
| PCBD2 | FOXN3 | 0.759973 | 3 | 0 | 3 |
| PCBD2 | NCKAP1 | 0.738934 | 3 | 0 | 3 |
| PCBD2 | THRB | 0.734976 | 3 | 0 | 3 |
| PCBD2 | TOM1 | 0.730793 | 4 | 0 | 4 |
| PCBD2 | IL10RB | 0.729786 | 3 | 0 | 3 |
| PCBD2 | TIAM1 | 0.72914 | 4 | 0 | 4 |
| PCBD2 | BDP1 | 0.728296 | 3 | 0 | 3 |
| PCBD2 | ORMDL2 | 0.726456 | 3 | 0 | 3 |
| PCBD2 | MNS1 | 0.718812 | 3 | 0 | 3 |
| PCBD2 | DLD | 0.718435 | 3 | 0 | 3 |
| PCBD2 | CLTB | 0.718038 | 5 | 0 | 5 |
| PCBD2 | DDI2 | 0.717278 | 3 | 0 | 3 |
| PCBD2 | ITPKC | 0.716928 | 4 | 0 | 3 |
| PCBD2 | LSM11 | 0.713785 | 4 | 0 | 4 |
| PCBD2 | PPA1 | 0.713687 | 3 | 0 | 3 |
| PCBD2 | EIF1B | 0.711872 | 3 | 0 | 3 |
| PCBD2 | ARRB1 | 0.708633 | 3 | 0 | 3 |
For details and further investigation, click here
