| Full name: zinc finger protein 395 | Alias Symbol: PRF-1|HDBP2|PBF|DKFZp434K1210 | ||
| Type: protein-coding gene | Cytoband: 8p21.1 | ||
| Entrez ID: 55893 | HGNC ID: HGNC:18737 | Ensembl Gene: ENSG00000186918 | OMIM ID: 609494 |
| Drug and gene relationship at DGIdb | |||
Expression of ZNF395:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ZNF395 | 55893 | 218149_s_at | -0.1532 | 0.7709 | |
| GSE20347 | ZNF395 | 55893 | 218149_s_at | -0.3215 | 0.2183 | |
| GSE23400 | ZNF395 | 55893 | 218149_s_at | -0.3330 | 0.0086 | |
| GSE26886 | ZNF395 | 55893 | 218149_s_at | -0.9413 | 0.0040 | |
| GSE29001 | ZNF395 | 55893 | 218149_s_at | -0.5014 | 0.1335 | |
| GSE38129 | ZNF395 | 55893 | 218149_s_at | -0.4024 | 0.0428 | |
| GSE45670 | ZNF395 | 55893 | 218149_s_at | -0.3869 | 0.0518 | |
| GSE53622 | ZNF395 | 55893 | 10601 | -0.7472 | 0.0000 | |
| GSE53624 | ZNF395 | 55893 | 10601 | -0.6879 | 0.0000 | |
| GSE63941 | ZNF395 | 55893 | 218149_s_at | -0.8798 | 0.2726 | |
| GSE77861 | ZNF395 | 55893 | 218149_s_at | -0.1925 | 0.6591 | |
| GSE97050 | ZNF395 | 55893 | A_23_P146077 | -0.6470 | 0.0737 | |
| SRP007169 | ZNF395 | 55893 | RNAseq | -1.0960 | 0.0022 | |
| SRP008496 | ZNF395 | 55893 | RNAseq | -1.0686 | 0.0000 | |
| SRP064894 | ZNF395 | 55893 | RNAseq | -0.6776 | 0.0029 | |
| SRP133303 | ZNF395 | 55893 | RNAseq | -1.0720 | 0.0000 | |
| SRP159526 | ZNF395 | 55893 | RNAseq | -1.2451 | 0.0000 | |
| SRP193095 | ZNF395 | 55893 | RNAseq | -0.4123 | 0.0182 | |
| SRP219564 | ZNF395 | 55893 | RNAseq | -1.1679 | 0.0404 | |
| TCGA | ZNF395 | 55893 | RNAseq | -0.0816 | 0.1888 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by ZNF395 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ZNF395:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ZNF395 | 55893 | 4 | 10 | 16 | |
| GSE20123 | ZNF395 | 55893 | 4 | 10 | 16 | |
| GSE43470 | ZNF395 | 55893 | 4 | 7 | 32 | |
| GSE46452 | ZNF395 | 55893 | 13 | 13 | 33 | |
| GSE47630 | ZNF395 | 55893 | 10 | 8 | 22 | |
| GSE54993 | ZNF395 | 55893 | 2 | 15 | 53 | |
| GSE54994 | ZNF395 | 55893 | 10 | 15 | 28 | |
| GSE60625 | ZNF395 | 55893 | 3 | 0 | 8 | |
| GSE74703 | ZNF395 | 55893 | 4 | 6 | 26 | |
| GSE74704 | ZNF395 | 55893 | 3 | 7 | 10 | |
| TCGA | ZNF395 | 55893 | 17 | 42 | 37 |
Total number of gains: 74; Total number of losses: 133; Total Number of normals: 281.
Somatic mutations of ZNF395:
Generating mutation plots.
Highly correlated genes for ZNF395:
Showing top 20/466 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ZNF395 | MRPL39 | 0.740938 | 3 | 0 | 3 |
| ZNF395 | RNASEL | 0.734243 | 3 | 0 | 3 |
| ZNF395 | C5orf51 | 0.725519 | 3 | 0 | 3 |
| ZNF395 | TMEM126A | 0.725137 | 3 | 0 | 3 |
| ZNF395 | PRPF38A | 0.719086 | 3 | 0 | 3 |
| ZNF395 | GGA3 | 0.712355 | 3 | 0 | 3 |
| ZNF395 | GIN1 | 0.709086 | 3 | 0 | 3 |
| ZNF395 | COG6 | 0.704254 | 3 | 0 | 3 |
| ZNF395 | ZNF564 | 0.70138 | 3 | 0 | 3 |
| ZNF395 | DUSP28 | 0.700847 | 3 | 0 | 3 |
| ZNF395 | FRMD6 | 0.700205 | 3 | 0 | 3 |
| ZNF395 | LEMD3 | 0.699739 | 3 | 0 | 3 |
| ZNF395 | CD59 | 0.69625 | 3 | 0 | 3 |
| ZNF395 | GATM | 0.689422 | 5 | 0 | 4 |
| ZNF395 | PTAR1 | 0.688707 | 3 | 0 | 3 |
| ZNF395 | SLC10A5 | 0.687715 | 3 | 0 | 3 |
| ZNF395 | EIF2B1 | 0.686883 | 3 | 0 | 3 |
| ZNF395 | TBC1D22B | 0.686258 | 3 | 0 | 3 |
| ZNF395 | ZBTB1 | 0.681114 | 3 | 0 | 3 |
| ZNF395 | DCP1B | 0.6768 | 3 | 0 | 3 |
For details and further investigation, click here
