| Full name: galactokinase 2 | Alias Symbol: GK2 | ||
| Type: protein-coding gene | Cytoband: 15q21.1-q21.2 | ||
| Entrez ID: 2585 | HGNC ID: HGNC:4119 | Ensembl Gene: ENSG00000156958 | OMIM ID: 137028 |
| Drug and gene relationship at DGIdb | |||
Expression of GALK2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GALK2 | 2585 | 205219_s_at | -0.1003 | 0.8733 | |
| GSE20347 | GALK2 | 2585 | 205219_s_at | 0.4043 | 0.0181 | |
| GSE23400 | GALK2 | 2585 | 205219_s_at | 0.2212 | 0.0005 | |
| GSE26886 | GALK2 | 2585 | 205219_s_at | -0.5964 | 0.0194 | |
| GSE29001 | GALK2 | 2585 | 205219_s_at | 0.3815 | 0.1786 | |
| GSE38129 | GALK2 | 2585 | 205219_s_at | 0.4786 | 0.0016 | |
| GSE45670 | GALK2 | 2585 | 205219_s_at | 0.2461 | 0.1391 | |
| GSE53622 | GALK2 | 2585 | 42384 | -0.6718 | 0.0001 | |
| GSE53624 | GALK2 | 2585 | 42384 | -0.5522 | 0.0000 | |
| GSE63941 | GALK2 | 2585 | 205219_s_at | 1.0566 | 0.0051 | |
| GSE77861 | GALK2 | 2585 | 205219_s_at | 0.0315 | 0.9251 | |
| GSE97050 | GALK2 | 2585 | A_23_P48807 | -0.0333 | 0.9069 | |
| SRP007169 | GALK2 | 2585 | RNAseq | -0.0539 | 0.9106 | |
| SRP008496 | GALK2 | 2585 | RNAseq | 0.4122 | 0.2335 | |
| SRP064894 | GALK2 | 2585 | RNAseq | 0.3568 | 0.0228 | |
| SRP133303 | GALK2 | 2585 | RNAseq | 0.1689 | 0.2558 | |
| SRP159526 | GALK2 | 2585 | RNAseq | 0.2395 | 0.4930 | |
| SRP193095 | GALK2 | 2585 | RNAseq | -0.1206 | 0.4025 | |
| SRP219564 | GALK2 | 2585 | RNAseq | 0.2052 | 0.5682 | |
| TCGA | GALK2 | 2585 | RNAseq | -0.0119 | 0.8433 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by GALK2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GALK2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GALK2 | 2585 | 5 | 3 | 22 | |
| GSE20123 | GALK2 | 2585 | 5 | 3 | 22 | |
| GSE43470 | GALK2 | 2585 | 5 | 4 | 34 | |
| GSE46452 | GALK2 | 2585 | 3 | 7 | 49 | |
| GSE47630 | GALK2 | 2585 | 8 | 10 | 22 | |
| GSE54993 | GALK2 | 2585 | 4 | 6 | 60 | |
| GSE54994 | GALK2 | 2585 | 5 | 7 | 41 | |
| GSE60625 | GALK2 | 2585 | 4 | 0 | 7 | |
| GSE74703 | GALK2 | 2585 | 5 | 3 | 28 | |
| GSE74704 | GALK2 | 2585 | 2 | 3 | 15 | |
| TCGA | GALK2 | 2585 | 9 | 16 | 71 |
Total number of gains: 55; Total number of losses: 62; Total Number of normals: 371.
Somatic mutations of GALK2:
Generating mutation plots.
Highly correlated genes for GALK2:
Showing top 20/47 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GALK2 | IGFL2 | 0.784901 | 3 | 0 | 3 |
| GALK2 | TNNT2 | 0.709679 | 3 | 0 | 3 |
| GALK2 | ZNF501 | 0.672881 | 3 | 0 | 3 |
| GALK2 | SLC35F3 | 0.671743 | 3 | 0 | 3 |
| GALK2 | FBXO22 | 0.668417 | 4 | 0 | 3 |
| GALK2 | ARFGEF1 | 0.655761 | 3 | 0 | 3 |
| GALK2 | NLRP13 | 0.64831 | 3 | 0 | 3 |
| GALK2 | SLC27A5 | 0.642259 | 4 | 0 | 3 |
| GALK2 | SLC20A2 | 0.636237 | 4 | 0 | 3 |
| GALK2 | RP1L1 | 0.629068 | 3 | 0 | 3 |
| GALK2 | TMEM242 | 0.61877 | 3 | 0 | 3 |
| GALK2 | PRAME | 0.595702 | 5 | 0 | 3 |
| GALK2 | LRRC1 | 0.592078 | 4 | 0 | 4 |
| GALK2 | TGFA | 0.588902 | 4 | 0 | 4 |
| GALK2 | PRPF6 | 0.584447 | 4 | 0 | 3 |
| GALK2 | PSMB5 | 0.57227 | 7 | 0 | 5 |
| GALK2 | HCAR3 | 0.568592 | 4 | 0 | 3 |
| GALK2 | MSX2 | 0.558685 | 4 | 0 | 3 |
| GALK2 | DIABLO | 0.556263 | 6 | 0 | 4 |
| GALK2 | GPN2 | 0.555292 | 6 | 0 | 4 |
For details and further investigation, click here
