TCFL5

 

Full name: transcription factor like 5 Alias Symbol: Figlb|E2BP-1|CHA|bHLHe82
Type: protein-coding gene Cytoband: 20q13.33
Entrez ID: 10732 HGNC ID: HGNC:11646 Ensembl Gene: ENSG00000101190 OMIM ID: 604745
Drug and gene relationship at DGIdb

 

Expression of TCFL5:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 TCFL5 10732 204849_at 1.0128 0.1074
GSE20347 TCFL5 10732 204849_at 0.9514 0.0000
GSE23400 TCFL5 10732 204849_at 0.8610 0.0000
GSE26886 TCFL5 10732 204849_at 0.5488 0.1864
GSE29001 TCFL5 10732 204849_at 1.1602 0.0018
GSE38129 TCFL5 10732 204849_at 0.7958 0.0001
GSE45670 TCFL5 10732 204849_at 0.5095 0.0940
GSE53622 TCFL5 10732 23129 0.1479 0.0175
GSE53624 TCFL5 10732 23129 0.1627 0.0024
GSE63941 TCFL5 10732 204849_at 0.1284 0.8813
GSE77861 TCFL5 10732 204849_at 0.3900 0.4807
GSE97050 TCFL5 10732 A_23_P143147 0.0999 0.8037
SRP007169 TCFL5 10732 RNAseq 0.3702 0.4332
SRP008496 TCFL5 10732 RNAseq 0.6526 0.0945
SRP064894 TCFL5 10732 RNAseq 1.0324 0.0000
SRP133303 TCFL5 10732 RNAseq 0.8511 0.0000
SRP159526 TCFL5 10732 RNAseq 0.9777 0.0189
SRP193095 TCFL5 10732 RNAseq 0.8995 0.0000
SRP219564 TCFL5 10732 RNAseq 0.7969 0.0780
TCGA TCFL5 10732 RNAseq 0.1767 0.0043

Upregulated datasets: 2; Downregulated datasets: 0.  

 

Survival by TCFL5 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of TCFL5:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 TCFL5 10732 14 2 14
GSE20123 TCFL5 10732 14 2 14
GSE43470 TCFL5 10732 11 1 31
GSE46452 TCFL5 10732 35 0 24
GSE47630 TCFL5 10732 25 1 14
GSE54993 TCFL5 10732 0 16 54
GSE54994 TCFL5 10732 29 0 24
GSE60625 TCFL5 10732 0 0 11
GSE74703 TCFL5 10732 10 0 26
GSE74704 TCFL5 10732 11 0 9
TCGA TCFL5 10732 43 4 49

Total number of gains: 192; Total number of losses: 26; Total Number of normals: 270.  

 

Somatic mutations of TCFL5:

 

Generating mutation plots.

 

Highly correlated genes for TCFL5:

 

Showing top 20/284 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
TCFL5ARMC10.705023606
TCFL5ICE10.669194707
TCFL5HOMER30.658482705
TCFL5GPR1800.655232303
TCFL5GNPDA10.646641705
TCFL5SNAI20.64321610010
TCFL5MRGBP0.637798807
TCFL5PLEKHA80.636876303
TCFL5LOXL20.634924605
TCFL5ERH0.632817907
TCFL5CDCA7L0.632301403
TCFL5CBX30.632227907
TCFL5TAF40.6319211108
TCFL5SERPINH10.629902807
TCFL5TTK0.629074605
TCFL5CCNB10.627519605
TCFL5CDKN30.624635807
TCFL5CDC25B0.623297705
TCFL5SNX100.622829806
TCFL5DESI20.62173706

For details and further investigation, click here