YEATS4

 

Full name: YEATS domain containing 4 Alias Symbol: NuBI-1|GAS41|YAF9
Type: protein-coding gene Cytoband: 12q15
Entrez ID: 8089 HGNC ID: HGNC:24859 Ensembl Gene: ENSG00000127337 OMIM ID: 602116
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of YEATS4:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 YEATS4 8089 218911_at 0.3654 0.4374
GSE20347 YEATS4 8089 218911_at 0.6186 0.0024
GSE23400 YEATS4 8089 218911_at 0.2704 0.0001
GSE26886 YEATS4 8089 218911_at 0.7447 0.0151
GSE29001 YEATS4 8089 218911_at 0.9230 0.0227
GSE38129 YEATS4 8089 218911_at 0.8954 0.0000
GSE45670 YEATS4 8089 218911_at 0.1660 0.4502
GSE53622 YEATS4 8089 42389 0.4762 0.0000
GSE53624 YEATS4 8089 42389 0.4768 0.0000
GSE63941 YEATS4 8089 218911_at 1.0371 0.2050
GSE77861 YEATS4 8089 218911_at 0.2626 0.1898
GSE97050 YEATS4 8089 A_23_P87591 0.4182 0.2276
SRP007169 YEATS4 8089 RNAseq 0.3141 0.4265
SRP008496 YEATS4 8089 RNAseq 0.3440 0.2083
SRP064894 YEATS4 8089 RNAseq 0.5203 0.0408
SRP133303 YEATS4 8089 RNAseq 1.2820 0.0016
SRP159526 YEATS4 8089 RNAseq 0.3644 0.2283
SRP193095 YEATS4 8089 RNAseq 0.2454 0.1305
TCGA YEATS4 8089 RNAseq 0.3178 0.0001

Upregulated datasets: 1; Downregulated datasets: 0.  


 

Survival by YEATS4 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  


Copy number change of YEATS4:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 YEATS4 8089 6 1 23
GSE20123 YEATS4 8089 6 0 24
GSE43470 YEATS4 8089 5 0 38
GSE46452 YEATS4 8089 11 1 47
GSE47630 YEATS4 8089 10 1 29
GSE54993 YEATS4 8089 0 6 64
GSE54994 YEATS4 8089 7 1 45
GSE60625 YEATS4 8089 0 0 11
GSE74703 YEATS4 8089 5 0 31
GSE74704 YEATS4 8089 5 0 15
TCGA YEATS4 8089 23 8 65

Total number of gains: 78; Total number of losses: 18; Total Number of normals: 392.  


 

Somatic mutations of YEATS4:

 

Generating mutation plots.

 

Highly correlated genes for YEATS4:

 

Showing top 20/322 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
YEATS4BCAP310.708346303
YEATS4POC1A0.660318504
YEATS4OIP50.6596891007
YEATS4ARHGAP210.656101403
YEATS4PAG10.649806303
YEATS4TBC1D70.643072503
YEATS4EDEM30.642329504
YEATS4C15orf400.639742403
YEATS4DYNC1LI10.636059403
YEATS4MED200.633982605
YEATS4ZSCAN5A0.629587505
YEATS4TANK0.628135403
YEATS4SLC5A60.624543504
YEATS4SEC620.623432303
YEATS4ZNF5590.621205505
YEATS4SF3A30.618333403
YEATS4BTBD30.616516604
YEATS4ACTR3B0.616436705
YEATS4CCDC340.614163706
YEATS4TFB2M0.6138921008

For details and further investigation, click here