| Full name: dynein light chain roadblock-type 2 | Alias Symbol: DNLC2B|ROBLD2 | ||
| Type: protein-coding gene | Cytoband: 16q23.2 | ||
| Entrez ID: 83657 | HGNC ID: HGNC:15467 | Ensembl Gene: ENSG00000168589 | OMIM ID: 607168 |
| Drug and gene relationship at DGIdb | |||
Expression of DYNLRB2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | DYNLRB2 | 83657 | 238116_at | -0.3240 | 0.4223 | |
| GSE26886 | DYNLRB2 | 83657 | 238116_at | 0.3106 | 0.2130 | |
| GSE45670 | DYNLRB2 | 83657 | 238116_at | -0.3525 | 0.0800 | |
| GSE53622 | DYNLRB2 | 83657 | 4367 | -0.4937 | 0.0000 | |
| GSE53624 | DYNLRB2 | 83657 | 38728 | -0.4833 | 0.0000 | |
| GSE63941 | DYNLRB2 | 83657 | 238116_at | 0.0571 | 0.9524 | |
| GSE77861 | DYNLRB2 | 83657 | 238116_at | -0.2139 | 0.1067 | |
| GSE97050 | DYNLRB2 | 83657 | A_33_P3276630 | -0.0599 | 0.8225 | |
| TCGA | DYNLRB2 | 83657 | RNAseq | 0.0810 | 0.8984 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by DYNLRB2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of DYNLRB2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | DYNLRB2 | 83657 | 4 | 3 | 23 | |
| GSE20123 | DYNLRB2 | 83657 | 4 | 3 | 23 | |
| GSE43470 | DYNLRB2 | 83657 | 2 | 8 | 33 | |
| GSE46452 | DYNLRB2 | 83657 | 37 | 2 | 20 | |
| GSE47630 | DYNLRB2 | 83657 | 11 | 8 | 21 | |
| GSE54993 | DYNLRB2 | 83657 | 2 | 4 | 64 | |
| GSE54994 | DYNLRB2 | 83657 | 7 | 10 | 36 | |
| GSE60625 | DYNLRB2 | 83657 | 4 | 0 | 7 | |
| GSE74703 | DYNLRB2 | 83657 | 2 | 6 | 28 | |
| GSE74704 | DYNLRB2 | 83657 | 3 | 2 | 15 | |
| TCGA | DYNLRB2 | 83657 | 24 | 15 | 57 |
Total number of gains: 100; Total number of losses: 61; Total Number of normals: 327.
Somatic mutations of DYNLRB2:
Generating mutation plots.
Highly correlated genes for DYNLRB2:
Showing top 20/58 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| DYNLRB2 | SOS2 | 0.746111 | 3 | 0 | 3 |
| DYNLRB2 | NTN4 | 0.68979 | 3 | 0 | 3 |
| DYNLRB2 | LINC00933 | 0.689183 | 3 | 0 | 3 |
| DYNLRB2 | CAPNS2 | 0.65355 | 3 | 0 | 3 |
| DYNLRB2 | LIMCH1 | 0.629462 | 3 | 0 | 3 |
| DYNLRB2 | ZMAT1 | 0.628531 | 4 | 0 | 4 |
| DYNLRB2 | RPL10L | 0.612622 | 5 | 0 | 3 |
| DYNLRB2 | CCSER2 | 0.600248 | 3 | 0 | 3 |
| DYNLRB2 | TMEM40 | 0.589116 | 4 | 0 | 3 |
| DYNLRB2 | HES1 | 0.587359 | 4 | 0 | 4 |
| DYNLRB2 | SLC25A21-AS1 | 0.58253 | 3 | 0 | 3 |
| DYNLRB2 | FAM228B | 0.581869 | 6 | 0 | 3 |
| DYNLRB2 | RASSF5 | 0.581003 | 4 | 0 | 3 |
| DYNLRB2 | METTL25 | 0.579028 | 3 | 0 | 3 |
| DYNLRB2 | COLGALT2 | 0.577525 | 3 | 0 | 3 |
| DYNLRB2 | FYCO1 | 0.57725 | 3 | 0 | 3 |
| DYNLRB2 | TP53I3 | 0.575069 | 4 | 0 | 3 |
| DYNLRB2 | IGBP1 | 0.574778 | 4 | 0 | 3 |
| DYNLRB2 | INSL3 | 0.568982 | 3 | 0 | 3 |
| DYNLRB2 | EIF4E3 | 0.563247 | 4 | 0 | 3 |
For details and further investigation, click here
