| Full name: LIM and calponin homology domains 1 | Alias Symbol: DKFZP686A01247|LIMCH1A|LMO7B | ||
| Type: protein-coding gene | Cytoband: 4p13 | ||
| Entrez ID: 22998 | HGNC ID: HGNC:29191 | Ensembl Gene: ENSG00000064042 | OMIM ID: 617750 |
| Drug and gene relationship at DGIdb | |||
Expression of LIMCH1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LIMCH1 | 22998 | 212327_at | -1.2397 | 0.2842 | |
| GSE20347 | LIMCH1 | 22998 | 212328_at | -2.2645 | 0.0000 | |
| GSE23400 | LIMCH1 | 22998 | 212327_at | -0.5794 | 0.0001 | |
| GSE26886 | LIMCH1 | 22998 | 212328_at | -0.9466 | 0.0563 | |
| GSE29001 | LIMCH1 | 22998 | 212328_at | -1.6032 | 0.0016 | |
| GSE38129 | LIMCH1 | 22998 | 212328_at | -1.9542 | 0.0000 | |
| GSE45670 | LIMCH1 | 22998 | 212328_at | -1.4928 | 0.0008 | |
| GSE53622 | LIMCH1 | 22998 | 46339 | -1.3966 | 0.0000 | |
| GSE53624 | LIMCH1 | 22998 | 45083 | -1.0672 | 0.0000 | |
| GSE63941 | LIMCH1 | 22998 | 212328_at | -1.5153 | 0.3064 | |
| GSE77861 | LIMCH1 | 22998 | 212327_at | -0.8811 | 0.0210 | |
| GSE97050 | LIMCH1 | 22998 | A_32_P117354 | -1.3732 | 0.0640 | |
| SRP007169 | LIMCH1 | 22998 | RNAseq | 0.1188 | 0.8455 | |
| SRP008496 | LIMCH1 | 22998 | RNAseq | 0.1625 | 0.7206 | |
| SRP064894 | LIMCH1 | 22998 | RNAseq | -0.6641 | 0.0178 | |
| SRP133303 | LIMCH1 | 22998 | RNAseq | -1.1946 | 0.0000 | |
| SRP159526 | LIMCH1 | 22998 | RNAseq | -1.1871 | 0.0001 | |
| SRP193095 | LIMCH1 | 22998 | RNAseq | -1.0459 | 0.0000 | |
| SRP219564 | LIMCH1 | 22998 | RNAseq | -0.3574 | 0.6031 | |
| TCGA | LIMCH1 | 22998 | RNAseq | -0.5316 | 0.0010 |
Upregulated datasets: 0; Downregulated datasets: 9.
Survival by LIMCH1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LIMCH1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LIMCH1 | 22998 | 0 | 16 | 14 | |
| GSE20123 | LIMCH1 | 22998 | 0 | 16 | 14 | |
| GSE43470 | LIMCH1 | 22998 | 0 | 14 | 29 | |
| GSE46452 | LIMCH1 | 22998 | 1 | 36 | 22 | |
| GSE47630 | LIMCH1 | 22998 | 1 | 19 | 20 | |
| GSE54993 | LIMCH1 | 22998 | 7 | 0 | 63 | |
| GSE54994 | LIMCH1 | 22998 | 4 | 9 | 40 | |
| GSE60625 | LIMCH1 | 22998 | 0 | 0 | 11 | |
| GSE74703 | LIMCH1 | 22998 | 0 | 12 | 24 | |
| GSE74704 | LIMCH1 | 22998 | 0 | 9 | 11 | |
| TCGA | LIMCH1 | 22998 | 11 | 43 | 42 |
Total number of gains: 24; Total number of losses: 174; Total Number of normals: 290.
Somatic mutations of LIMCH1:
Generating mutation plots.
Highly correlated genes for LIMCH1:
Showing top 20/1343 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LIMCH1 | ANAPC16 | 0.749305 | 3 | 0 | 3 |
| LIMCH1 | TANC1 | 0.744073 | 3 | 0 | 3 |
| LIMCH1 | RAB9B | 0.743469 | 5 | 0 | 5 |
| LIMCH1 | ANGPTL1 | 0.741628 | 5 | 0 | 5 |
| LIMCH1 | FBXO42 | 0.729707 | 3 | 0 | 3 |
| LIMCH1 | PDCD4 | 0.723175 | 4 | 0 | 4 |
| LIMCH1 | CYP21A2 | 0.718757 | 3 | 0 | 3 |
| LIMCH1 | CRIP1 | 0.715485 | 3 | 0 | 3 |
| LIMCH1 | C7 | 0.713888 | 9 | 0 | 9 |
| LIMCH1 | WDR48 | 0.710953 | 4 | 0 | 3 |
| LIMCH1 | ZMAT1 | 0.705629 | 6 | 0 | 6 |
| LIMCH1 | ZNF608 | 0.704394 | 4 | 0 | 4 |
| LIMCH1 | PARP16 | 0.700925 | 4 | 0 | 4 |
| LIMCH1 | XKR4 | 0.700429 | 5 | 0 | 5 |
| LIMCH1 | EPB41L4A | 0.698262 | 4 | 0 | 4 |
| LIMCH1 | ASPA | 0.695252 | 10 | 0 | 10 |
| LIMCH1 | CYP4V2 | 0.694111 | 3 | 0 | 3 |
| LIMCH1 | UBE2Q2 | 0.693369 | 3 | 0 | 3 |
| LIMCH1 | SORCS1 | 0.693195 | 4 | 0 | 4 |
| LIMCH1 | RCOR3 | 0.69264 | 5 | 0 | 5 |
For details and further investigation, click here
