| Full name: matrix metallopeptidase 23B | Alias Symbol: MIFR|MIFR-1 | ||
| Type: protein-coding gene | Cytoband: 1p36.33 | ||
| Entrez ID: 8510 | HGNC ID: HGNC:7171 | Ensembl Gene: ENSG00000189409 | OMIM ID: 603321 |
| Drug and gene relationship at DGIdb | |||
Expression of MMP23B:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE53622 | MMP23B | 8510 | 173521 | 0.2411 | 0.1537 | |
| GSE53624 | MMP23B | 8510 | 173521 | 0.3436 | 0.0111 | |
| GSE97050 | MMP23B | 8510 | A_23_P74088 | 0.3931 | 0.2858 | |
| SRP064894 | MMP23B | 8510 | RNAseq | 0.7992 | 0.0847 | |
| SRP133303 | MMP23B | 8510 | RNAseq | 0.4688 | 0.2102 | |
| SRP159526 | MMP23B | 8510 | RNAseq | 0.2791 | 0.6148 | |
| SRP219564 | MMP23B | 8510 | RNAseq | 0.6696 | 0.3783 | |
| TCGA | MMP23B | 8510 | RNAseq | -0.2287 | 0.2166 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MMP23B expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MMP23B:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | MMP23B | 8510 | 3 | 7 | 20 | |
| GSE20123 | MMP23B | 8510 | 3 | 6 | 21 | |
| GSE43470 | MMP23B | 8510 | 3 | 5 | 35 | |
| GSE46452 | MMP23B | 8510 | 7 | 1 | 51 | |
| GSE47630 | MMP23B | 8510 | 8 | 4 | 28 | |
| GSE54993 | MMP23B | 8510 | 2 | 2 | 66 | |
| GSE54994 | MMP23B | 8510 | 15 | 2 | 36 | |
| GSE60625 | MMP23B | 8510 | 0 | 0 | 11 | |
| GSE74703 | MMP23B | 8510 | 3 | 3 | 30 | |
| GSE74704 | MMP23B | 8510 | 3 | 0 | 17 | |
| TCGA | MMP23B | 8510 | 14 | 20 | 62 |
Total number of gains: 61; Total number of losses: 50; Total Number of normals: 377.
Somatic mutations of MMP23B:
Generating mutation plots.
Highly correlated genes for MMP23B:
Showing all 19 correlated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MMP23B | ECM2 | 0.708282 | 3 | 0 | 3 |
| MMP23B | EMILIN1 | 0.700927 | 3 | 0 | 3 |
| MMP23B | MSR1 | 0.660599 | 3 | 0 | 3 |
| MMP23B | LAIR2 | 0.659979 | 3 | 0 | 3 |
| MMP23B | CHSY3 | 0.659946 | 3 | 0 | 3 |
| MMP23B | IGSF21 | 0.65485 | 3 | 0 | 3 |
| MMP23B | BCL6B | 0.643793 | 3 | 0 | 3 |
| MMP23B | TBXAS1 | 0.63968 | 3 | 0 | 3 |
| MMP23B | RARRES2 | 0.635453 | 4 | 0 | 3 |
| MMP23B | SIRPA | 0.633906 | 3 | 0 | 3 |
| MMP23B | S100A4 | 0.633664 | 3 | 0 | 3 |
| MMP23B | FMNL1 | 0.626672 | 3 | 0 | 3 |
| MMP23B | IL10RA | 0.617478 | 3 | 0 | 3 |
| MMP23B | MS4A4E | 0.602472 | 3 | 0 | 3 |
| MMP23B | AK5 | 0.585903 | 3 | 0 | 3 |
| MMP23B | C2 | 0.580586 | 3 | 0 | 3 |
| MMP23B | CALHM2 | 0.579096 | 3 | 0 | 3 |
| MMP23B | HOXB5 | 0.573699 | 4 | 0 | 3 |
| MMP23B | SFRP4 | 0.505191 | 4 | 0 | 3 |
For details and further investigation, click here
