| Full name: eukaryotic translation elongation factor 1 alpha 2 | Alias Symbol: EEF1AL|HS1 | ||
| Type: protein-coding gene | Cytoband: 20q13.33 | ||
| Entrez ID: 1917 | HGNC ID: HGNC:3192 | Ensembl Gene: ENSG00000101210 | OMIM ID: 602959 |
| Drug and gene relationship at DGIdb | |||
EEF1A2 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa05134 | Legionellosis |
Expression of EEF1A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EEF1A2 | 1917 | 204540_at | -0.6976 | 0.0571 | |
| GSE20347 | EEF1A2 | 1917 | 204540_at | 0.0979 | 0.7793 | |
| GSE23400 | EEF1A2 | 1917 | 204540_at | -0.1265 | 0.1073 | |
| GSE26886 | EEF1A2 | 1917 | 204540_at | -0.0628 | 0.7973 | |
| GSE29001 | EEF1A2 | 1917 | 204540_at | 0.0182 | 0.9079 | |
| GSE38129 | EEF1A2 | 1917 | 204540_at | 0.0646 | 0.8207 | |
| GSE45670 | EEF1A2 | 1917 | 204540_at | -0.1018 | 0.4014 | |
| GSE53622 | EEF1A2 | 1917 | 65105 | -0.3228 | 0.1666 | |
| GSE53624 | EEF1A2 | 1917 | 65105 | -0.3025 | 0.0735 | |
| GSE63941 | EEF1A2 | 1917 | 204540_at | 2.6214 | 0.1163 | |
| GSE77861 | EEF1A2 | 1917 | 204540_at | -0.1083 | 0.6659 | |
| GSE97050 | EEF1A2 | 1917 | A_33_P3229953 | -0.6481 | 0.2934 | |
| SRP007169 | EEF1A2 | 1917 | RNAseq | -1.9246 | 0.2549 | |
| SRP064894 | EEF1A2 | 1917 | RNAseq | -2.0060 | 0.0000 | |
| SRP133303 | EEF1A2 | 1917 | RNAseq | 1.3817 | 0.1040 | |
| SRP159526 | EEF1A2 | 1917 | RNAseq | 0.7901 | 0.3487 | |
| SRP219564 | EEF1A2 | 1917 | RNAseq | -3.8525 | 0.0000 | |
| TCGA | EEF1A2 | 1917 | RNAseq | -0.9409 | 0.0142 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by EEF1A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EEF1A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EEF1A2 | 1917 | 14 | 2 | 14 | |
| GSE20123 | EEF1A2 | 1917 | 14 | 2 | 14 | |
| GSE43470 | EEF1A2 | 1917 | 11 | 1 | 31 | |
| GSE46452 | EEF1A2 | 1917 | 35 | 0 | 24 | |
| GSE47630 | EEF1A2 | 1917 | 25 | 1 | 14 | |
| GSE54993 | EEF1A2 | 1917 | 0 | 17 | 53 | |
| GSE54994 | EEF1A2 | 1917 | 29 | 0 | 24 | |
| GSE60625 | EEF1A2 | 1917 | 0 | 0 | 11 | |
| GSE74703 | EEF1A2 | 1917 | 10 | 0 | 26 | |
| GSE74704 | EEF1A2 | 1917 | 11 | 0 | 9 | |
| TCGA | EEF1A2 | 1917 | 44 | 4 | 48 |
Total number of gains: 193; Total number of losses: 27; Total Number of normals: 268.
Somatic mutations of EEF1A2:
Generating mutation plots.
Highly correlated genes for EEF1A2:
Showing top 20/134 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EEF1A2 | DYNLT3 | 0.740743 | 3 | 0 | 3 |
| EEF1A2 | UBE2D2 | 0.714342 | 3 | 0 | 3 |
| EEF1A2 | CUL3 | 0.711044 | 3 | 0 | 3 |
| EEF1A2 | TRAPPC3 | 0.700934 | 3 | 0 | 3 |
| EEF1A2 | FAM122A | 0.700199 | 3 | 0 | 3 |
| EEF1A2 | TSPYL1 | 0.692399 | 3 | 0 | 3 |
| EEF1A2 | RNF185 | 0.690364 | 3 | 0 | 3 |
| EEF1A2 | PPP2R2A | 0.685899 | 3 | 0 | 3 |
| EEF1A2 | TBL1Y | 0.684624 | 3 | 0 | 3 |
| EEF1A2 | DHX32 | 0.682295 | 3 | 0 | 3 |
| EEF1A2 | CCNC | 0.678626 | 4 | 0 | 4 |
| EEF1A2 | RORA | 0.674721 | 3 | 0 | 3 |
| EEF1A2 | MDFIC | 0.667061 | 3 | 0 | 3 |
| EEF1A2 | FAR1 | 0.665561 | 3 | 0 | 3 |
| EEF1A2 | WSB1 | 0.661581 | 3 | 0 | 3 |
| EEF1A2 | FAM71F2 | 0.655846 | 3 | 0 | 3 |
| EEF1A2 | FAM47A | 0.655415 | 3 | 0 | 3 |
| EEF1A2 | PLEKHM1 | 0.651739 | 4 | 0 | 4 |
| EEF1A2 | MCTS1 | 0.651614 | 3 | 0 | 3 |
| EEF1A2 | LMO2 | 0.650667 | 3 | 0 | 3 |
For details and further investigation, click here
