| Full name: MCTS1 re-initiation and release factor | Alias Symbol: MCT-1 | ||
| Type: protein-coding gene | Cytoband: Xq24 | ||
| Entrez ID: 28985 | HGNC ID: HGNC:23357 | Ensembl Gene: ENSG00000232119 | OMIM ID: 300587 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of MCTS1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | MCTS1 | 28985 | 218163_at | -0.6084 | 0.1698 | |
| GSE20347 | MCTS1 | 28985 | 218163_at | -0.3177 | 0.1939 | |
| GSE23400 | MCTS1 | 28985 | 218163_at | 0.1152 | 0.1695 | |
| GSE26886 | MCTS1 | 28985 | 218163_at | 0.1159 | 0.5780 | |
| GSE29001 | MCTS1 | 28985 | 218163_at | -0.3282 | 0.3037 | |
| GSE38129 | MCTS1 | 28985 | 218163_at | 0.1154 | 0.5825 | |
| GSE45670 | MCTS1 | 28985 | 218163_at | 0.3610 | 0.0190 | |
| GSE53622 | MCTS1 | 28985 | 85023 | 0.1371 | 0.0322 | |
| GSE53624 | MCTS1 | 28985 | 85023 | 0.1613 | 0.0278 | |
| GSE63941 | MCTS1 | 28985 | 218163_at | 0.5928 | 0.0606 | |
| GSE77861 | MCTS1 | 28985 | 218163_at | -0.2185 | 0.5519 | |
| GSE97050 | MCTS1 | 28985 | A_23_P114282 | 0.2817 | 0.4008 | |
| SRP007169 | MCTS1 | 28985 | RNAseq | -0.9049 | 0.0357 | |
| SRP008496 | MCTS1 | 28985 | RNAseq | -0.3545 | 0.3989 | |
| SRP064894 | MCTS1 | 28985 | RNAseq | -0.0131 | 0.9308 | |
| SRP133303 | MCTS1 | 28985 | RNAseq | 0.3096 | 0.1409 | |
| SRP159526 | MCTS1 | 28985 | RNAseq | -0.1615 | 0.4660 | |
| SRP193095 | MCTS1 | 28985 | RNAseq | -0.2405 | 0.0009 | |
| SRP219564 | MCTS1 | 28985 | RNAseq | 0.0270 | 0.9390 | |
| TCGA | MCTS1 | 28985 | RNAseq | 0.0213 | 0.6696 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by MCTS1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of MCTS1:
No record found for this gene.
Somatic mutations of MCTS1:
Generating mutation plots.
Highly correlated genes for MCTS1:
Showing top 20/570 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| MCTS1 | PTGR1 | 0.849255 | 3 | 0 | 3 |
| MCTS1 | SLC16A14 | 0.83013 | 3 | 0 | 3 |
| MCTS1 | ZDHHC21 | 0.826694 | 3 | 0 | 3 |
| MCTS1 | TTC39B | 0.815591 | 3 | 0 | 3 |
| MCTS1 | TRAF6 | 0.763345 | 3 | 0 | 3 |
| MCTS1 | CCNDBP1 | 0.757102 | 4 | 0 | 4 |
| MCTS1 | EIF5A | 0.741791 | 3 | 0 | 3 |
| MCTS1 | AP1B1 | 0.740935 | 3 | 0 | 3 |
| MCTS1 | MDFIC | 0.72924 | 3 | 0 | 3 |
| MCTS1 | OSBPL2 | 0.728667 | 3 | 0 | 3 |
| MCTS1 | ARL2BP | 0.726081 | 5 | 0 | 5 |
| MCTS1 | RREB1 | 0.724246 | 3 | 0 | 3 |
| MCTS1 | RHBDF1 | 0.722521 | 3 | 0 | 3 |
| MCTS1 | VPS4B | 0.719723 | 4 | 0 | 4 |
| MCTS1 | EZR | 0.714261 | 3 | 0 | 3 |
| MCTS1 | SCOC | 0.713038 | 3 | 0 | 3 |
| MCTS1 | APOOL | 0.709527 | 3 | 0 | 3 |
| MCTS1 | UBE2J1 | 0.703016 | 4 | 0 | 3 |
| MCTS1 | LYSMD3 | 0.702649 | 4 | 0 | 3 |
| MCTS1 | GALNT1 | 0.699255 | 4 | 0 | 3 |
For details and further investigation, click here
