| Full name: EF-hand calcium binding domain 1 | Alias Symbol: FLJ11767 | ||
| Type: protein-coding gene | Cytoband: 8q11.21 | ||
| Entrez ID: 79645 | HGNC ID: HGNC:25678 | Ensembl Gene: ENSG00000034239 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EFCAB1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFCAB1 | 79645 | 220156_at | 0.0277 | 0.9402 | |
| GSE20347 | EFCAB1 | 79645 | 220156_at | 0.1668 | 0.1800 | |
| GSE23400 | EFCAB1 | 79645 | 220156_at | 0.0077 | 0.8550 | |
| GSE26886 | EFCAB1 | 79645 | 220156_at | -0.2185 | 0.0397 | |
| GSE29001 | EFCAB1 | 79645 | 220156_at | -0.0537 | 0.8295 | |
| GSE38129 | EFCAB1 | 79645 | 220156_at | 0.0473 | 0.6887 | |
| GSE45670 | EFCAB1 | 79645 | 220156_at | 0.0985 | 0.5538 | |
| GSE53622 | EFCAB1 | 79645 | 108834 | 0.3053 | 0.0023 | |
| GSE53624 | EFCAB1 | 79645 | 108834 | 0.2283 | 0.0011 | |
| GSE63941 | EFCAB1 | 79645 | 220156_at | 0.1398 | 0.4691 | |
| GSE77861 | EFCAB1 | 79645 | 220156_at | 0.1287 | 0.2706 | |
| GSE97050 | EFCAB1 | 79645 | A_33_P3214988 | 0.2153 | 0.7029 | |
| SRP064894 | EFCAB1 | 79645 | RNAseq | 1.0682 | 0.0159 | |
| SRP133303 | EFCAB1 | 79645 | RNAseq | 0.2952 | 0.2931 | |
| SRP159526 | EFCAB1 | 79645 | RNAseq | 1.1361 | 0.0574 | |
| SRP193095 | EFCAB1 | 79645 | RNAseq | 0.7676 | 0.0035 | |
| SRP219564 | EFCAB1 | 79645 | RNAseq | -0.4542 | 0.2046 | |
| TCGA | EFCAB1 | 79645 | RNAseq | 1.2667 | 0.0003 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by EFCAB1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFCAB1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFCAB1 | 79645 | 15 | 1 | 14 | |
| GSE20123 | EFCAB1 | 79645 | 15 | 1 | 14 | |
| GSE43470 | EFCAB1 | 79645 | 13 | 3 | 27 | |
| GSE46452 | EFCAB1 | 79645 | 21 | 3 | 35 | |
| GSE47630 | EFCAB1 | 79645 | 21 | 2 | 17 | |
| GSE54993 | EFCAB1 | 79645 | 1 | 16 | 53 | |
| GSE54994 | EFCAB1 | 79645 | 28 | 0 | 25 | |
| GSE60625 | EFCAB1 | 79645 | 0 | 5 | 6 | |
| GSE74703 | EFCAB1 | 79645 | 12 | 2 | 22 | |
| GSE74704 | EFCAB1 | 79645 | 11 | 0 | 9 | |
| TCGA | EFCAB1 | 79645 | 46 | 8 | 42 |
Total number of gains: 183; Total number of losses: 41; Total Number of normals: 264.
Somatic mutations of EFCAB1:
Generating mutation plots.
Highly correlated genes for EFCAB1:
Showing top 20/77 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFCAB1 | FABP7 | 0.713121 | 4 | 0 | 4 |
| EFCAB1 | GYPB | 0.675923 | 3 | 0 | 3 |
| EFCAB1 | FGF4 | 0.643009 | 4 | 0 | 3 |
| EFCAB1 | ZNF343 | 0.638881 | 4 | 0 | 4 |
| EFCAB1 | PAK3 | 0.623176 | 4 | 0 | 3 |
| EFCAB1 | NPTX2 | 0.608498 | 4 | 0 | 3 |
| EFCAB1 | ART3 | 0.60097 | 5 | 0 | 3 |
| EFCAB1 | SPPL2B | 0.598438 | 3 | 0 | 3 |
| EFCAB1 | ATAT1 | 0.597485 | 3 | 0 | 3 |
| EFCAB1 | GRAMD1B | 0.597264 | 3 | 0 | 3 |
| EFCAB1 | MAGEB4 | 0.596181 | 3 | 0 | 3 |
| EFCAB1 | SPINK4 | 0.592849 | 3 | 0 | 3 |
| EFCAB1 | TBX21 | 0.592312 | 3 | 0 | 3 |
| EFCAB1 | LRRC43 | 0.589018 | 3 | 0 | 3 |
| EFCAB1 | ACTB | 0.584342 | 3 | 0 | 3 |
| EFCAB1 | MUC3B | 0.581314 | 3 | 0 | 3 |
| EFCAB1 | SULT1E1 | 0.580485 | 4 | 0 | 3 |
| EFCAB1 | CNTN2 | 0.577199 | 5 | 0 | 4 |
| EFCAB1 | SYS1 | 0.576379 | 3 | 0 | 3 |
| EFCAB1 | ARPP21 | 0.572965 | 3 | 0 | 3 |
For details and further investigation, click here
