| Full name: glycophorin B (MNS blood group) | Alias Symbol: GPB|SS|CD235b | ||
| Type: protein-coding gene | Cytoband: 4q31.21 | ||
| Entrez ID: 2994 | HGNC ID: HGNC:4703 | Ensembl Gene: ENSG00000250361 | OMIM ID: 617923 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of GYPB:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GYPB | 2994 | 207459_x_at | 0.0725 | 0.7096 | |
| GSE20347 | GYPB | 2994 | 216833_x_at | -0.0711 | 0.3025 | |
| GSE23400 | GYPB | 2994 | 207459_x_at | -0.0799 | 0.0252 | |
| GSE26886 | GYPB | 2994 | 207459_x_at | -0.2693 | 0.0043 | |
| GSE29001 | GYPB | 2994 | 214407_x_at | -0.0884 | 0.5085 | |
| GSE38129 | GYPB | 2994 | 216833_x_at | -0.1495 | 0.0419 | |
| GSE45670 | GYPB | 2994 | 207459_x_at | 0.0920 | 0.3387 | |
| GSE53622 | GYPB | 2994 | 86574 | -0.2006 | 0.2083 | |
| GSE53624 | GYPB | 2994 | 35545 | -2.5514 | 0.0000 | |
| GSE63941 | GYPB | 2994 | 216833_x_at | 0.0815 | 0.5644 | |
| GSE77861 | GYPB | 2994 | 216398_at | 0.0416 | 0.7247 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by GYPB expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GYPB:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GYPB | 2994 | 0 | 12 | 18 | |
| GSE20123 | GYPB | 2994 | 0 | 12 | 18 | |
| GSE43470 | GYPB | 2994 | 0 | 13 | 30 | |
| GSE46452 | GYPB | 2994 | 1 | 36 | 22 | |
| GSE47630 | GYPB | 2994 | 0 | 22 | 18 | |
| GSE54993 | GYPB | 2994 | 10 | 0 | 60 | |
| GSE54994 | GYPB | 2994 | 2 | 11 | 40 | |
| GSE60625 | GYPB | 2994 | 0 | 1 | 10 | |
| GSE74703 | GYPB | 2994 | 0 | 11 | 25 | |
| GSE74704 | GYPB | 2994 | 0 | 6 | 14 | |
| TCGA | GYPB | 2994 | 13 | 30 | 53 |
Total number of gains: 26; Total number of losses: 154; Total Number of normals: 308.
Somatic mutations of GYPB:
Generating mutation plots.
Highly correlated genes for GYPB:
Showing top 20/709 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GYPB | LUZP4 | 0.737044 | 4 | 0 | 4 |
| GYPB | CALCR | 0.726137 | 5 | 0 | 5 |
| GYPB | TAL1 | 0.725475 | 4 | 0 | 4 |
| GYPB | KDM5C | 0.71853 | 3 | 0 | 3 |
| GYPB | MEPE | 0.704466 | 4 | 0 | 4 |
| GYPB | KRTAP5-8 | 0.701113 | 6 | 0 | 5 |
| GYPB | STXBP6 | 0.694319 | 3 | 0 | 3 |
| GYPB | OR10H3 | 0.693693 | 5 | 0 | 5 |
| GYPB | MAS1 | 0.692876 | 5 | 0 | 5 |
| GYPB | GREB1L | 0.691259 | 3 | 0 | 3 |
| GYPB | KIR2DS2 | 0.690577 | 4 | 0 | 4 |
| GYPB | RNF17 | 0.689952 | 5 | 0 | 5 |
| GYPB | LRTM1 | 0.689938 | 4 | 0 | 4 |
| GYPB | MYO1A | 0.68811 | 5 | 0 | 5 |
| GYPB | CBL | 0.687705 | 4 | 0 | 4 |
| GYPB | IFNA17 | 0.683396 | 6 | 0 | 6 |
| GYPB | CLDN9 | 0.675942 | 5 | 0 | 5 |
| GYPB | EFCAB1 | 0.675923 | 3 | 0 | 3 |
| GYPB | TCP10L | 0.673686 | 4 | 0 | 4 |
| GYPB | NEURL1 | 0.672641 | 4 | 0 | 4 |
For details and further investigation, click here
