| Full name: ADP-ribosyltransferase 3 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q21.1 | ||
| Entrez ID: 419 | HGNC ID: HGNC:725 | Ensembl Gene: ENSG00000156219 | OMIM ID: 603086 |
| Drug and gene relationship at DGIdb | |||
Expression of ART3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ART3 | 419 | 210147_at | -0.3507 | 0.6497 | |
| GSE20347 | ART3 | 419 | 210147_at | 0.2790 | 0.3875 | |
| GSE23400 | ART3 | 419 | 210147_at | -0.0631 | 0.0067 | |
| GSE26886 | ART3 | 419 | 210147_at | 0.0792 | 0.3534 | |
| GSE29001 | ART3 | 419 | 210147_at | 0.0459 | 0.8399 | |
| GSE38129 | ART3 | 419 | 210147_at | -0.0559 | 0.8169 | |
| GSE45670 | ART3 | 419 | 210147_at | -0.2046 | 0.1768 | |
| GSE53622 | ART3 | 419 | 99301 | -0.5791 | 0.0004 | |
| GSE53624 | ART3 | 419 | 17532 | -1.3744 | 0.0000 | |
| GSE63941 | ART3 | 419 | 210147_at | 0.0109 | 0.9765 | |
| GSE77861 | ART3 | 419 | 210147_at | -0.1400 | 0.1212 | |
| GSE97050 | ART3 | 419 | A_33_P3723448 | -0.1379 | 0.7063 | |
| TCGA | ART3 | 419 | RNAseq | -0.3427 | 0.6622 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ART3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ART3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ART3 | 419 | 2 | 9 | 19 | |
| GSE20123 | ART3 | 419 | 2 | 9 | 19 | |
| GSE43470 | ART3 | 419 | 0 | 13 | 30 | |
| GSE46452 | ART3 | 419 | 1 | 36 | 22 | |
| GSE47630 | ART3 | 419 | 1 | 19 | 20 | |
| GSE54993 | ART3 | 419 | 7 | 0 | 63 | |
| GSE54994 | ART3 | 419 | 0 | 9 | 44 | |
| GSE60625 | ART3 | 419 | 0 | 0 | 11 | |
| GSE74703 | ART3 | 419 | 0 | 11 | 25 | |
| GSE74704 | ART3 | 419 | 2 | 5 | 13 | |
| TCGA | ART3 | 419 | 17 | 30 | 49 |
Total number of gains: 32; Total number of losses: 141; Total Number of normals: 315.
Somatic mutations of ART3:
Generating mutation plots.
Highly correlated genes for ART3:
Showing top 20/106 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ART3 | MYBPC1 | 0.795382 | 3 | 0 | 3 |
| ART3 | WDR19 | 0.676188 | 3 | 0 | 3 |
| ART3 | HAND2-AS1 | 0.649943 | 5 | 0 | 3 |
| ART3 | SCUBE3 | 0.647461 | 3 | 0 | 3 |
| ART3 | SNAP91 | 0.630512 | 4 | 0 | 4 |
| ART3 | CSN2 | 0.627482 | 5 | 0 | 3 |
| ART3 | ARHGAP6 | 0.620445 | 3 | 0 | 3 |
| ART3 | GFRA1 | 0.614522 | 7 | 0 | 4 |
| ART3 | ESRRG | 0.614216 | 4 | 0 | 3 |
| ART3 | ACTN2 | 0.61244 | 5 | 0 | 3 |
| ART3 | CSN3 | 0.611091 | 6 | 0 | 3 |
| ART3 | NSUN7 | 0.6092 | 3 | 0 | 3 |
| ART3 | CASQ1 | 0.60882 | 5 | 0 | 4 |
| ART3 | MYT1L | 0.607331 | 4 | 0 | 3 |
| ART3 | ZNF529 | 0.606621 | 4 | 0 | 3 |
| ART3 | MC4R | 0.604796 | 5 | 0 | 4 |
| ART3 | MIA | 0.603164 | 6 | 0 | 3 |
| ART3 | THPO | 0.602028 | 4 | 0 | 4 |
| ART3 | FIBIN | 0.60165 | 3 | 0 | 3 |
| ART3 | EPHA7 | 0.601187 | 5 | 0 | 3 |
For details and further investigation, click here
