| Full name: EF-hand calcium binding domain 6 | Alias Symbol: FLJ23588|DJBP|HSCBCIP1|KIAA1672|dJ185D5.1 | ||
| Type: protein-coding gene | Cytoband: 22q13.2-q13.31 | ||
| Entrez ID: 64800 | HGNC ID: HGNC:24204 | Ensembl Gene: ENSG00000186976 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of EFCAB6:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EFCAB6 | 64800 | 220271_x_at | 0.0885 | 0.7297 | |
| GSE20347 | EFCAB6 | 64800 | 220271_x_at | -0.0099 | 0.9080 | |
| GSE23400 | EFCAB6 | 64800 | 220271_x_at | -0.0496 | 0.1279 | |
| GSE26886 | EFCAB6 | 64800 | 220271_x_at | -0.0416 | 0.7078 | |
| GSE29001 | EFCAB6 | 64800 | 220271_x_at | -0.1042 | 0.3671 | |
| GSE38129 | EFCAB6 | 64800 | 220271_x_at | -0.1134 | 0.0969 | |
| GSE45670 | EFCAB6 | 64800 | 220271_x_at | -0.0319 | 0.7317 | |
| GSE53622 | EFCAB6 | 64800 | 8710 | -0.4576 | 0.0065 | |
| GSE53624 | EFCAB6 | 64800 | 8710 | -0.7756 | 0.0000 | |
| GSE63941 | EFCAB6 | 64800 | 220271_x_at | -0.0610 | 0.7407 | |
| GSE77861 | EFCAB6 | 64800 | 220271_x_at | -0.0069 | 0.9702 | |
| SRP064894 | EFCAB6 | 64800 | RNAseq | -0.2524 | 0.3716 | |
| SRP133303 | EFCAB6 | 64800 | RNAseq | -0.6958 | 0.0035 | |
| SRP159526 | EFCAB6 | 64800 | RNAseq | 0.1658 | 0.7952 | |
| SRP193095 | EFCAB6 | 64800 | RNAseq | -0.2579 | 0.2906 | |
| TCGA | EFCAB6 | 64800 | RNAseq | -1.0021 | 0.0025 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by EFCAB6 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EFCAB6:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EFCAB6 | 64800 | 5 | 7 | 18 | |
| GSE20123 | EFCAB6 | 64800 | 5 | 6 | 19 | |
| GSE43470 | EFCAB6 | 64800 | 3 | 6 | 34 | |
| GSE46452 | EFCAB6 | 64800 | 31 | 2 | 26 | |
| GSE47630 | EFCAB6 | 64800 | 9 | 4 | 27 | |
| GSE54993 | EFCAB6 | 64800 | 3 | 6 | 61 | |
| GSE54994 | EFCAB6 | 64800 | 11 | 8 | 34 | |
| GSE60625 | EFCAB6 | 64800 | 5 | 0 | 6 | |
| GSE74703 | EFCAB6 | 64800 | 3 | 4 | 29 | |
| GSE74704 | EFCAB6 | 64800 | 2 | 3 | 15 | |
| TCGA | EFCAB6 | 64800 | 26 | 16 | 54 |
Total number of gains: 103; Total number of losses: 62; Total Number of normals: 323.
Somatic mutations of EFCAB6:
Generating mutation plots.
Highly correlated genes for EFCAB6:
Showing top 20/243 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EFCAB6 | USP20 | 0.684778 | 3 | 0 | 3 |
| EFCAB6 | PSPN | 0.670227 | 3 | 0 | 3 |
| EFCAB6 | CHST8 | 0.660538 | 3 | 0 | 3 |
| EFCAB6 | CD5L | 0.642813 | 4 | 0 | 3 |
| EFCAB6 | PHF21B | 0.641729 | 3 | 0 | 3 |
| EFCAB6 | HRH3 | 0.63688 | 4 | 0 | 4 |
| EFCAB6 | SLC27A1 | 0.631462 | 3 | 0 | 3 |
| EFCAB6 | ITGB3 | 0.629748 | 4 | 0 | 3 |
| EFCAB6 | C20orf141 | 0.62943 | 3 | 0 | 3 |
| EFCAB6 | C1orf68 | 0.626949 | 3 | 0 | 3 |
| EFCAB6 | HTR1D | 0.62457 | 4 | 0 | 3 |
| EFCAB6 | MPPED1 | 0.623696 | 3 | 0 | 3 |
| EFCAB6 | FRS3 | 0.623664 | 4 | 0 | 3 |
| EFCAB6 | EPHB1 | 0.622751 | 5 | 0 | 4 |
| EFCAB6 | KCNE1 | 0.620168 | 4 | 0 | 3 |
| EFCAB6 | ZNF771 | 0.616921 | 6 | 0 | 4 |
| EFCAB6 | PRB1 | 0.615863 | 4 | 0 | 4 |
| EFCAB6 | RBP2 | 0.611825 | 4 | 0 | 3 |
| EFCAB6 | OR2H2 | 0.609995 | 5 | 0 | 4 |
| EFCAB6 | KIF25-AS1 | 0.609305 | 4 | 0 | 3 |
For details and further investigation, click here
