| Full name: eukaryotic translation initiation factor 2A | Alias Symbol: EIF-2A | ||
| Type: protein-coding gene | Cytoband: 3q25.1 | ||
| Entrez ID: 83939 | HGNC ID: HGNC:3254 | Ensembl Gene: ENSG00000144895 | OMIM ID: 609234 |
Expression of EIF2A:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EIF2A | 83939 | 223015_at | 0.0719 | 0.7944 | |
| GSE26886 | EIF2A | 83939 | 223015_at | 0.2792 | 0.1207 | |
| GSE45670 | EIF2A | 83939 | 223015_at | -0.1435 | 0.3682 | |
| GSE53622 | EIF2A | 83939 | 37130 | 0.3302 | 0.0000 | |
| GSE53624 | EIF2A | 83939 | 37130 | 0.3247 | 0.0000 | |
| GSE63941 | EIF2A | 83939 | 223015_at | 1.0311 | 0.0208 | |
| GSE77861 | EIF2A | 83939 | 223015_at | 0.0219 | 0.9332 | |
| GSE97050 | EIF2A | 83939 | A_23_P44932 | 0.4791 | 0.1751 | |
| SRP007169 | EIF2A | 83939 | RNAseq | -0.1097 | 0.7434 | |
| SRP008496 | EIF2A | 83939 | RNAseq | 0.0419 | 0.8418 | |
| SRP064894 | EIF2A | 83939 | RNAseq | -0.0384 | 0.8217 | |
| SRP133303 | EIF2A | 83939 | RNAseq | 0.3211 | 0.0705 | |
| SRP159526 | EIF2A | 83939 | RNAseq | 0.1424 | 0.7103 | |
| SRP193095 | EIF2A | 83939 | RNAseq | -0.1166 | 0.3737 | |
| SRP219564 | EIF2A | 83939 | RNAseq | -0.1532 | 0.6757 | |
| TCGA | EIF2A | 83939 | RNAseq | 0.0758 | 0.0969 |
Upregulated datasets: 1; Downregulated datasets: 0.
Survival by EIF2A expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of EIF2A:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EIF2A | 83939 | 21 | 0 | 9 | |
| GSE20123 | EIF2A | 83939 | 21 | 0 | 9 | |
| GSE43470 | EIF2A | 83939 | 23 | 0 | 20 | |
| GSE46452 | EIF2A | 83939 | 18 | 2 | 39 | |
| GSE47630 | EIF2A | 83939 | 19 | 3 | 18 | |
| GSE54993 | EIF2A | 83939 | 1 | 10 | 59 | |
| GSE54994 | EIF2A | 83939 | 37 | 1 | 15 | |
| GSE60625 | EIF2A | 83939 | 0 | 6 | 5 | |
| GSE74703 | EIF2A | 83939 | 20 | 0 | 16 | |
| GSE74704 | EIF2A | 83939 | 14 | 0 | 6 | |
| TCGA | EIF2A | 83939 | 72 | 1 | 23 |
Total number of gains: 246; Total number of losses: 23; Total Number of normals: 219.
Somatic mutations of EIF2A:
Generating mutation plots.
Highly correlated genes for EIF2A:
Showing top 20/270 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EIF2A | NAIP | 0.765981 | 3 | 0 | 3 |
| EIF2A | STON2 | 0.747807 | 3 | 0 | 3 |
| EIF2A | RNF149 | 0.733657 | 3 | 0 | 3 |
| EIF2A | SP140L | 0.714283 | 3 | 0 | 3 |
| EIF2A | CBLC | 0.710006 | 3 | 0 | 3 |
| EIF2A | CHD7 | 0.707358 | 3 | 0 | 3 |
| EIF2A | S1PR5 | 0.705653 | 3 | 0 | 3 |
| EIF2A | LAMP3 | 0.700068 | 3 | 0 | 3 |
| EIF2A | NCEH1 | 0.698112 | 3 | 0 | 3 |
| EIF2A | CTU2 | 0.6975 | 3 | 0 | 3 |
| EIF2A | GOLGA5 | 0.697408 | 3 | 0 | 3 |
| EIF2A | FUCA2 | 0.696929 | 3 | 0 | 3 |
| EIF2A | HSD17B12 | 0.694527 | 3 | 0 | 3 |
| EIF2A | EPB41L5 | 0.677283 | 4 | 0 | 3 |
| EIF2A | EIF2S1 | 0.67512 | 3 | 0 | 3 |
| EIF2A | TCERG1 | 0.670952 | 4 | 0 | 3 |
| EIF2A | GTF3C2 | 0.669365 | 3 | 0 | 3 |
| EIF2A | RSL1D1 | 0.668992 | 4 | 0 | 3 |
| EIF2A | NMI | 0.668754 | 3 | 0 | 3 |
| EIF2A | COPB1 | 0.668352 | 4 | 0 | 4 |
For details and further investigation, click here
