| Full name: SP140 nuclear body protein like | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2q37.1 | ||
| Entrez ID: 93349 | HGNC ID: HGNC:25105 | Ensembl Gene: ENSG00000185404 | OMIM ID: 617747 |
| Drug and gene relationship at DGIdb | |||
Expression of SP140L:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SP140L | 93349 | 214791_at | 0.6801 | 0.2300 | |
| GSE20347 | SP140L | 93349 | 214791_at | 1.0053 | 0.0000 | |
| GSE23400 | SP140L | 93349 | 214791_at | 0.7855 | 0.0000 | |
| GSE26886 | SP140L | 93349 | 214791_at | 0.7800 | 0.0787 | |
| GSE29001 | SP140L | 93349 | 214791_at | 0.9391 | 0.0055 | |
| GSE38129 | SP140L | 93349 | 214791_at | 0.7242 | 0.0001 | |
| GSE45670 | SP140L | 93349 | 214791_at | 1.0339 | 0.0000 | |
| GSE53622 | SP140L | 93349 | 19112 | 0.6760 | 0.0000 | |
| GSE53624 | SP140L | 93349 | 19112 | 0.7993 | 0.0000 | |
| GSE63941 | SP140L | 93349 | 214791_at | -0.0189 | 0.9788 | |
| GSE77861 | SP140L | 93349 | 214791_at | 0.8923 | 0.0231 | |
| GSE97050 | SP140L | 93349 | A_23_P337753 | 1.0011 | 0.1502 | |
| SRP007169 | SP140L | 93349 | RNAseq | 1.1742 | 0.0088 | |
| SRP008496 | SP140L | 93349 | RNAseq | 0.7219 | 0.0377 | |
| SRP064894 | SP140L | 93349 | RNAseq | 0.9540 | 0.0000 | |
| SRP133303 | SP140L | 93349 | RNAseq | 0.7188 | 0.0000 | |
| SRP159526 | SP140L | 93349 | RNAseq | 0.4113 | 0.3311 | |
| SRP193095 | SP140L | 93349 | RNAseq | 1.0190 | 0.0000 | |
| SRP219564 | SP140L | 93349 | RNAseq | 1.1533 | 0.0000 | |
| TCGA | SP140L | 93349 | RNAseq | 0.3133 | 0.0009 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by SP140L expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SP140L:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SP140L | 93349 | 1 | 13 | 16 | |
| GSE20123 | SP140L | 93349 | 1 | 13 | 16 | |
| GSE43470 | SP140L | 93349 | 2 | 8 | 33 | |
| GSE46452 | SP140L | 93349 | 0 | 5 | 54 | |
| GSE47630 | SP140L | 93349 | 4 | 5 | 31 | |
| GSE54993 | SP140L | 93349 | 2 | 2 | 66 | |
| GSE54994 | SP140L | 93349 | 6 | 11 | 36 | |
| GSE60625 | SP140L | 93349 | 0 | 3 | 8 | |
| GSE74703 | SP140L | 93349 | 2 | 6 | 28 | |
| GSE74704 | SP140L | 93349 | 1 | 6 | 13 | |
| TCGA | SP140L | 93349 | 13 | 27 | 56 |
Total number of gains: 32; Total number of losses: 99; Total Number of normals: 357.
Somatic mutations of SP140L:
Generating mutation plots.
Highly correlated genes for SP140L:
Showing top 20/1056 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SP140L | SP140 | 0.860967 | 3 | 0 | 3 |
| SP140L | FANCD2 | 0.771554 | 3 | 0 | 3 |
| SP140L | FRMD8 | 0.751323 | 4 | 0 | 4 |
| SP140L | EIF2A | 0.714283 | 3 | 0 | 3 |
| SP140L | KDM2A | 0.708776 | 3 | 0 | 3 |
| SP140L | ALG1 | 0.708171 | 4 | 0 | 4 |
| SP140L | BPNT1 | 0.707669 | 4 | 0 | 4 |
| SP140L | GPR160 | 0.705996 | 3 | 0 | 3 |
| SP140L | PNPO | 0.7057 | 3 | 0 | 3 |
| SP140L | RNMT | 0.700331 | 3 | 0 | 3 |
| SP140L | HPS4 | 0.699178 | 4 | 0 | 3 |
| SP140L | USF1 | 0.699106 | 4 | 0 | 4 |
| SP140L | CDCA2 | 0.698382 | 4 | 0 | 4 |
| SP140L | CCDC15 | 0.694901 | 4 | 0 | 4 |
| SP140L | HS6ST1 | 0.69394 | 4 | 0 | 3 |
| SP140L | USP41 | 0.692068 | 3 | 0 | 3 |
| SP140L | MGAT2 | 0.690266 | 4 | 0 | 3 |
| SP140L | WNT10A | 0.689783 | 3 | 0 | 3 |
| SP140L | TMEM138 | 0.689128 | 6 | 0 | 6 |
| SP140L | LSM14B | 0.686165 | 3 | 0 | 3 |
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