| Full name: alpha-L-fucosidase 2 | Alias Symbol: MGC1314|dJ20N2.5 | ||
| Type: protein-coding gene | Cytoband: 6q24.2 | ||
| Entrez ID: 2519 | HGNC ID: HGNC:4008 | Ensembl Gene: ENSG00000001036 | OMIM ID: 136820 |
| Drug and gene relationship at DGIdb | |||
Expression of FUCA2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FUCA2 | 2519 | 223120_at | 0.4529 | 0.1928 | |
| GSE26886 | FUCA2 | 2519 | 223120_at | -0.0356 | 0.8572 | |
| GSE45670 | FUCA2 | 2519 | 223120_at | 0.6340 | 0.0005 | |
| GSE53622 | FUCA2 | 2519 | 50543 | 0.5965 | 0.0000 | |
| GSE53624 | FUCA2 | 2519 | 50543 | 0.8211 | 0.0000 | |
| GSE63941 | FUCA2 | 2519 | 223120_at | -0.3999 | 0.7820 | |
| GSE77861 | FUCA2 | 2519 | 223120_at | 1.0174 | 0.0007 | |
| GSE97050 | FUCA2 | 2519 | A_23_P145408 | 0.5625 | 0.1585 | |
| SRP007169 | FUCA2 | 2519 | RNAseq | 1.7009 | 0.0000 | |
| SRP008496 | FUCA2 | 2519 | RNAseq | 1.2969 | 0.0000 | |
| SRP064894 | FUCA2 | 2519 | RNAseq | 1.0806 | 0.0000 | |
| SRP133303 | FUCA2 | 2519 | RNAseq | 0.6576 | 0.0000 | |
| SRP159526 | FUCA2 | 2519 | RNAseq | 0.7682 | 0.0035 | |
| SRP193095 | FUCA2 | 2519 | RNAseq | 0.4765 | 0.0165 | |
| SRP219564 | FUCA2 | 2519 | RNAseq | 1.0524 | 0.0153 | |
| TCGA | FUCA2 | 2519 | RNAseq | -0.0671 | 0.2616 |
Upregulated datasets: 5; Downregulated datasets: 0.
Survival by FUCA2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FUCA2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FUCA2 | 2519 | 2 | 4 | 24 | |
| GSE20123 | FUCA2 | 2519 | 2 | 3 | 25 | |
| GSE43470 | FUCA2 | 2519 | 5 | 0 | 38 | |
| GSE46452 | FUCA2 | 2519 | 3 | 10 | 46 | |
| GSE47630 | FUCA2 | 2519 | 9 | 4 | 27 | |
| GSE54993 | FUCA2 | 2519 | 3 | 2 | 65 | |
| GSE54994 | FUCA2 | 2519 | 8 | 8 | 37 | |
| GSE60625 | FUCA2 | 2519 | 0 | 1 | 10 | |
| GSE74703 | FUCA2 | 2519 | 4 | 0 | 32 | |
| GSE74704 | FUCA2 | 2519 | 0 | 1 | 19 | |
| TCGA | FUCA2 | 2519 | 11 | 19 | 66 |
Total number of gains: 47; Total number of losses: 52; Total Number of normals: 389.
Somatic mutations of FUCA2:
Generating mutation plots.
Highly correlated genes for FUCA2:
Showing top 20/1596 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FUCA2 | ALKBH6 | 0.80144 | 4 | 0 | 4 |
| FUCA2 | IPO9 | 0.773876 | 3 | 0 | 3 |
| FUCA2 | DOT1L | 0.762685 | 3 | 0 | 3 |
| FUCA2 | U2SURP | 0.746067 | 4 | 0 | 4 |
| FUCA2 | KRTCAP2 | 0.743244 | 4 | 0 | 4 |
| FUCA2 | TSNAX | 0.737855 | 3 | 0 | 3 |
| FUCA2 | ACBD6 | 0.736554 | 4 | 0 | 4 |
| FUCA2 | XXYLT1 | 0.730031 | 4 | 0 | 4 |
| FUCA2 | MTERF3 | 0.729627 | 3 | 0 | 3 |
| FUCA2 | ARPC1B | 0.726458 | 6 | 0 | 6 |
| FUCA2 | RBM14 | 0.724051 | 3 | 0 | 3 |
| FUCA2 | C1R | 0.723772 | 3 | 0 | 3 |
| FUCA2 | LPCAT1 | 0.722817 | 6 | 0 | 6 |
| FUCA2 | CELF1 | 0.722604 | 3 | 0 | 3 |
| FUCA2 | MRPS12 | 0.721669 | 4 | 0 | 4 |
| FUCA2 | MSTO1 | 0.721621 | 4 | 0 | 3 |
| FUCA2 | CHD8 | 0.721065 | 4 | 0 | 4 |
| FUCA2 | YWHAH | 0.720311 | 5 | 0 | 5 |
| FUCA2 | DSCC1 | 0.718765 | 4 | 0 | 4 |
| FUCA2 | ACIN1 | 0.717351 | 4 | 0 | 4 |
For details and further investigation, click here
