| Full name: E74 like ETS transcription factor 5 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 11p13 | ||
| Entrez ID: 2001 | HGNC ID: HGNC:3320 | Ensembl Gene: ENSG00000135374 | OMIM ID: 605169 |
| Drug and gene relationship at DGIdb | |||
ELF5 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04917 | Prolactin signaling pathway |
Expression of ELF5:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ELF5 | 2001 | 220625_s_at | -0.0927 | 0.9037 | |
| GSE20347 | ELF5 | 2001 | 220625_s_at | 0.0297 | 0.8659 | |
| GSE23400 | ELF5 | 2001 | 220624_s_at | -0.1708 | 0.0000 | |
| GSE26886 | ELF5 | 2001 | 220625_s_at | -0.8652 | 0.0185 | |
| GSE29001 | ELF5 | 2001 | 220625_s_at | 0.6205 | 0.3736 | |
| GSE38129 | ELF5 | 2001 | 220625_s_at | 0.0456 | 0.8169 | |
| GSE45670 | ELF5 | 2001 | 220625_s_at | 0.1920 | 0.7061 | |
| GSE53622 | ELF5 | 2001 | 53816 | -0.3658 | 0.2277 | |
| GSE53624 | ELF5 | 2001 | 53816 | -0.9948 | 0.0000 | |
| GSE63941 | ELF5 | 2001 | 220624_s_at | 0.2640 | 0.5565 | |
| GSE77861 | ELF5 | 2001 | 220624_s_at | -0.0994 | 0.4424 | |
| SRP064894 | ELF5 | 2001 | RNAseq | -1.4823 | 0.0039 | |
| SRP133303 | ELF5 | 2001 | RNAseq | -0.6699 | 0.1787 | |
| SRP159526 | ELF5 | 2001 | RNAseq | 0.0201 | 0.9812 | |
| TCGA | ELF5 | 2001 | RNAseq | 0.0054 | 0.9939 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ELF5 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ELF5:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ELF5 | 2001 | 1 | 6 | 23 | |
| GSE20123 | ELF5 | 2001 | 1 | 5 | 24 | |
| GSE43470 | ELF5 | 2001 | 3 | 4 | 36 | |
| GSE46452 | ELF5 | 2001 | 7 | 5 | 47 | |
| GSE47630 | ELF5 | 2001 | 3 | 10 | 27 | |
| GSE54993 | ELF5 | 2001 | 3 | 2 | 65 | |
| GSE54994 | ELF5 | 2001 | 3 | 10 | 40 | |
| GSE60625 | ELF5 | 2001 | 0 | 0 | 11 | |
| GSE74703 | ELF5 | 2001 | 3 | 2 | 31 | |
| GSE74704 | ELF5 | 2001 | 0 | 3 | 17 | |
| TCGA | ELF5 | 2001 | 14 | 23 | 59 |
Total number of gains: 38; Total number of losses: 70; Total Number of normals: 380.
Somatic mutations of ELF5:
Generating mutation plots.
Highly correlated genes for ELF5:
Showing top 20/29 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ELF5 | CAMK1G | 0.67612 | 3 | 0 | 3 |
| ELF5 | CYLC1 | 0.675179 | 3 | 0 | 3 |
| ELF5 | AMPD1 | 0.647005 | 3 | 0 | 3 |
| ELF5 | OVGP1 | 0.634686 | 3 | 0 | 3 |
| ELF5 | ARHGEF38 | 0.630585 | 3 | 0 | 3 |
| ELF5 | THEG | 0.605055 | 3 | 0 | 3 |
| ELF5 | LRTOMT | 0.604116 | 3 | 0 | 3 |
| ELF5 | TCL1A | 0.59891 | 4 | 0 | 3 |
| ELF5 | FMO4 | 0.586999 | 3 | 0 | 3 |
| ELF5 | NXPE4 | 0.585544 | 5 | 0 | 3 |
| ELF5 | CYP4A11 | 0.571006 | 3 | 0 | 3 |
| ELF5 | CCL25 | 0.563974 | 4 | 0 | 3 |
| ELF5 | XCR1 | 0.562175 | 4 | 0 | 4 |
| ELF5 | LGALS13 | 0.551364 | 4 | 0 | 3 |
| ELF5 | MUC5B | 0.535889 | 5 | 0 | 3 |
| ELF5 | FA2H | 0.533873 | 8 | 0 | 4 |
| ELF5 | ABO | 0.533178 | 4 | 0 | 3 |
| ELF5 | VTCN1 | 0.532968 | 7 | 0 | 3 |
| ELF5 | C15orf39 | 0.531821 | 4 | 0 | 3 |
| ELF5 | AKAP7 | 0.53027 | 3 | 0 | 3 |
For details and further investigation, click here
