| Full name: fatty acid 2-hydroxylase | Alias Symbol: FAAH|FLJ25287 | ||
| Type: protein-coding gene | Cytoband: 16q23.1 | ||
| Entrez ID: 79152 | HGNC ID: HGNC:21197 | Ensembl Gene: ENSG00000103089 | OMIM ID: 611026 |
| Drug and gene relationship at DGIdb | |||
Expression of FA2H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | FA2H | 79152 | 219429_at | -0.5399 | 0.5750 | |
| GSE20347 | FA2H | 79152 | 219429_at | -0.4947 | 0.0306 | |
| GSE23400 | FA2H | 79152 | 219429_at | -0.3033 | 0.0005 | |
| GSE26886 | FA2H | 79152 | 219429_at | -1.3937 | 0.0001 | |
| GSE29001 | FA2H | 79152 | 219429_at | -0.7959 | 0.0037 | |
| GSE38129 | FA2H | 79152 | 219429_at | -0.3653 | 0.2159 | |
| GSE45670 | FA2H | 79152 | 219429_at | -0.2819 | 0.5644 | |
| GSE53622 | FA2H | 79152 | 18356 | -1.7585 | 0.0000 | |
| GSE53624 | FA2H | 79152 | 18356 | -1.6378 | 0.0000 | |
| GSE63941 | FA2H | 79152 | 219429_at | 2.3301 | 0.0497 | |
| GSE77861 | FA2H | 79152 | 219429_at | -0.1965 | 0.4754 | |
| SRP064894 | FA2H | 79152 | RNAseq | -2.5429 | 0.0000 | |
| SRP133303 | FA2H | 79152 | RNAseq | -0.6324 | 0.2746 | |
| SRP159526 | FA2H | 79152 | RNAseq | -0.8380 | 0.3126 | |
| SRP193095 | FA2H | 79152 | RNAseq | -1.1443 | 0.0212 | |
| SRP219564 | FA2H | 79152 | RNAseq | -1.4017 | 0.0111 | |
| TCGA | FA2H | 79152 | RNAseq | -1.3613 | 0.0000 |
Upregulated datasets: 1; Downregulated datasets: 7.
Survival by FA2H expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of FA2H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | FA2H | 79152 | 6 | 1 | 23 | |
| GSE20123 | FA2H | 79152 | 6 | 1 | 23 | |
| GSE43470 | FA2H | 79152 | 2 | 8 | 33 | |
| GSE46452 | FA2H | 79152 | 37 | 2 | 20 | |
| GSE47630 | FA2H | 79152 | 11 | 8 | 21 | |
| GSE54993 | FA2H | 79152 | 2 | 4 | 64 | |
| GSE54994 | FA2H | 79152 | 8 | 10 | 35 | |
| GSE60625 | FA2H | 79152 | 4 | 0 | 7 | |
| GSE74703 | FA2H | 79152 | 2 | 5 | 29 | |
| GSE74704 | FA2H | 79152 | 3 | 0 | 17 | |
| TCGA | FA2H | 79152 | 25 | 15 | 56 |
Total number of gains: 106; Total number of losses: 54; Total Number of normals: 328.
Somatic mutations of FA2H:
Generating mutation plots.
Highly correlated genes for FA2H:
Showing top 20/347 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| FA2H | MKRN1 | 0.700987 | 3 | 0 | 3 |
| FA2H | FAM3B | 0.655673 | 6 | 0 | 4 |
| FA2H | MACC1 | 0.649494 | 5 | 0 | 4 |
| FA2H | ST6GALNAC1 | 0.641987 | 6 | 0 | 4 |
| FA2H | STK40 | 0.639319 | 4 | 0 | 3 |
| FA2H | SLC44A3 | 0.634659 | 4 | 0 | 4 |
| FA2H | TRMT10A | 0.626447 | 4 | 0 | 3 |
| FA2H | ANXA11 | 0.623176 | 7 | 0 | 6 |
| FA2H | PKIB | 0.620319 | 4 | 0 | 3 |
| FA2H | MBOAT1 | 0.616712 | 4 | 0 | 3 |
| FA2H | MAGI3 | 0.61574 | 4 | 0 | 4 |
| FA2H | TAB3 | 0.614383 | 5 | 0 | 3 |
| FA2H | MYO5B | 0.61338 | 6 | 0 | 5 |
| FA2H | CBR3-AS1 | 0.613338 | 4 | 0 | 4 |
| FA2H | ADH6 | 0.612598 | 3 | 0 | 3 |
| FA2H | RGMA | 0.612451 | 5 | 0 | 4 |
| FA2H | SAMD13 | 0.61243 | 3 | 0 | 3 |
| FA2H | PRPF38A | 0.610021 | 3 | 0 | 3 |
| FA2H | KLB | 0.608882 | 5 | 0 | 4 |
| FA2H | LIPH | 0.605689 | 6 | 0 | 4 |
For details and further investigation, click here
