Full name: ETS transcription factor ELK1	Alias Symbol:
Type: protein-coding gene	Cytoband: Xp11.23
Entrez ID: 2002	HGNC ID: HGNC:3321	Ensembl Gene: ENSG00000126767	OMIM ID: 311040
Drug and gene relationship at DGIdb
Screen Evidence: Knocking out of this gene by CRIPR/Cas9 screen found 15/325 cell lines had fitness change in Project Score. Knocking out of this gene by CRIPR/Cas9 screen found altered tolerance on DNA toxicity in Genotoxic Screens.

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ELK1 involved pathways:

KEGG pathway	Description	View
hsa04010	MAPK signaling pathway	View
hsa04012	ErbB signaling pathway	View
hsa04014	Ras signaling pathway	View
hsa04510	Focal adhesion	View
hsa04910	Insulin signaling pathway	View
hsa04912	GnRH signaling pathway	View
hsa04921	Oxytocin signaling pathway	View
hsa05020	Prion diseases	View
hsa05140	Leishmaniasis	View
hsa05161	Hepatitis B	View
hsa05205	Proteoglycans in cancer	View
hsa05213	Endometrial cancer	View

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Expression of ELK1:

 

Dataset	Gene	EntrezID	Probe	Log2FC	Adj.pValue	Expression
GSE17351	ELK1	2002	203617_x_at	0.3581	0.2526	Show
GSE20347	ELK1	2002	203617_x_at	0.1717	0.0198	Show
GSE23400	ELK1	2002	203617_x_at	0.0699	0.0853	Show
GSE26886	ELK1	2002	203617_x_at	0.3758	0.0048	Show
GSE29001	ELK1	2002	203617_x_at	-0.1911	0.1684	Show
GSE38129	ELK1	2002	203617_x_at	0.1704	0.0798	Show
GSE45670	ELK1	2002	203617_x_at	0.1938	0.2182	Show
GSE53622	ELK1	2002	3827	0.3744	0.0000	Show
GSE53624	ELK1	2002	123917	0.7695	0.0000	Show
GSE63941	ELK1	2002	203617_x_at	-0.2423	0.3776	Show
GSE77861	ELK1	2002	203617_x_at	0.1114	0.4440	Show
GSE97050	ELK1	2002	A_33_P3386099	0.1514	0.4700	Show
SRP007169	ELK1	2002	RNAseq	0.6009	0.1269	Show
SRP008496	ELK1	2002	RNAseq	0.6327	0.0095	Show
SRP064894	ELK1	2002	RNAseq	0.5424	0.0030	Show
SRP133303	ELK1	2002	RNAseq	0.6676	0.0057	Show
SRP159526	ELK1	2002	RNAseq	0.8368	0.0000	Show
SRP193095	ELK1	2002	RNAseq	0.5660	0.0000	Show
SRP219564	ELK1	2002	RNAseq	0.4433	0.2201	Show
TCGA	ELK1	2002	RNAseq	0.1600	0.0030	Show

Upregulated datasets: 0; Downregulated datasets: 0.  Download Data

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Survival by ELK1 expression:

 

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Copy number change of ELK1:

 

No record found for this gene.

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Somatic mutations of ELK1:

 

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Highly correlated genes for ELK1:

 

Showing top 20/299 corelated genes with mean PCC>0.5.

Gene1	Gene2	Mean PCC	Num. Datasets	Num. PCC<0	Num. PCC>0.5
ELK1	GJA4	0.77197	3	0	3
ELK1	SLC45A3	0.730889	3	0	3
ELK1	STK11	0.713984	3	0	3
ELK1	DMTN	0.693555	3	0	3
ELK1	C9orf16	0.693219	4	0	4
ELK1	CTF1	0.682712	3	0	3
ELK1	WDR24	0.673342	4	0	3
ELK1	TBC1D25	0.65569	4	0	3
ELK1	YDJC	0.6516	5	0	5
ELK1	PPP2R5B	0.648349	7	0	6
ELK1	AP2A1	0.644897	3	0	3
ELK1	TAOK2	0.642611	4	0	3
ELK1	BMP8A	0.639477	4	0	3
ELK1	KDM6B	0.636699	3	0	3
ELK1	ANKRD52	0.635182	7	0	5
ELK1	CAPN15	0.634704	3	0	3
ELK1	MCM3AP	0.628725	3	0	3
ELK1	FMNL1	0.627392	4	0	4
ELK1	CHD5	0.62684	3	0	3
ELK1	RHEBL1	0.625452	4	0	3

For details and further investigation, click here