| Full name: calpain 15 | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 6650 | HGNC ID: HGNC:11182 | Ensembl Gene: ENSG00000103326 | OMIM ID: 603267 |
| Drug and gene relationship at DGIdb | |||
Expression of CAPN15:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CAPN15 | 6650 | 204275_at | 0.8778 | 0.1717 | |
| GSE20347 | CAPN15 | 6650 | 204275_at | 0.0486 | 0.8329 | |
| GSE23400 | CAPN15 | 6650 | 204275_at | 0.0520 | 0.5113 | |
| GSE26886 | CAPN15 | 6650 | 230295_at | 0.2644 | 0.0806 | |
| GSE29001 | CAPN15 | 6650 | 204275_at | -0.0627 | 0.6801 | |
| GSE38129 | CAPN15 | 6650 | 204275_at | 0.1509 | 0.3697 | |
| GSE45670 | CAPN15 | 6650 | 230295_at | 0.0102 | 0.9517 | |
| GSE63941 | CAPN15 | 6650 | 204275_at | 1.0590 | 0.0115 | |
| GSE77861 | CAPN15 | 6650 | 204275_at | 0.0597 | 0.7964 | |
| SRP007169 | CAPN15 | 6650 | RNAseq | -1.0769 | 0.0028 | |
| SRP008496 | CAPN15 | 6650 | RNAseq | -0.9869 | 0.0001 | |
| SRP064894 | CAPN15 | 6650 | RNAseq | -0.1729 | 0.4187 | |
| SRP133303 | CAPN15 | 6650 | RNAseq | 0.1380 | 0.4411 | |
| SRP159526 | CAPN15 | 6650 | RNAseq | -0.0613 | 0.7964 | |
| SRP193095 | CAPN15 | 6650 | RNAseq | 0.1562 | 0.3523 | |
| SRP219564 | CAPN15 | 6650 | RNAseq | 0.1591 | 0.6975 |
Upregulated datasets: 1; Downregulated datasets: 1.
Copy number change of CAPN15:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CAPN15 | 6650 | 5 | 5 | 20 | |
| GSE20123 | CAPN15 | 6650 | 5 | 4 | 21 | |
| GSE43470 | CAPN15 | 6650 | 4 | 7 | 32 | |
| GSE46452 | CAPN15 | 6650 | 38 | 1 | 20 | |
| GSE47630 | CAPN15 | 6650 | 13 | 6 | 21 | |
| GSE54993 | CAPN15 | 6650 | 3 | 5 | 62 | |
| GSE54994 | CAPN15 | 6650 | 4 | 10 | 39 | |
| GSE60625 | CAPN15 | 6650 | 4 | 0 | 7 | |
| GSE74703 | CAPN15 | 6650 | 4 | 5 | 27 | |
| GSE74704 | CAPN15 | 6650 | 3 | 2 | 15 | |
| TCGA | CAPN15 | 6650 | 20 | 15 | 61 |
Total number of gains: 103; Total number of losses: 60; Total Number of normals: 325.
Somatic mutations of CAPN15:
Generating mutation plots.
Highly correlated genes for CAPN15:
Showing top 20/121 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CAPN15 | MEN1 | 0.71116 | 3 | 0 | 3 |
| CAPN15 | CELF3 | 0.705191 | 3 | 0 | 3 |
| CAPN15 | ATP2A2 | 0.699508 | 4 | 0 | 4 |
| CAPN15 | ATXN2L | 0.689618 | 4 | 0 | 4 |
| CAPN15 | ECE2 | 0.682147 | 4 | 0 | 4 |
| CAPN15 | DCSTAMP | 0.67406 | 3 | 0 | 3 |
| CAPN15 | LEMD2 | 0.668308 | 3 | 0 | 3 |
| CAPN15 | BAIAP2L2 | 0.663562 | 3 | 0 | 3 |
| CAPN15 | TRAP1 | 0.654667 | 4 | 0 | 3 |
| CAPN15 | GLE1 | 0.646506 | 3 | 0 | 3 |
| CAPN15 | PTCRA | 0.645408 | 3 | 0 | 3 |
| CAPN15 | ELK1 | 0.634704 | 3 | 0 | 3 |
| CAPN15 | CDH15 | 0.634191 | 3 | 0 | 3 |
| CAPN15 | WDR5 | 0.62856 | 3 | 0 | 3 |
| CAPN15 | ELAVL3 | 0.623181 | 3 | 0 | 3 |
| CAPN15 | GART | 0.622432 | 4 | 0 | 3 |
| CAPN15 | SNCG | 0.61347 | 3 | 0 | 3 |
| CAPN15 | TAF4B | 0.611075 | 3 | 0 | 3 |
| CAPN15 | EEF1E1 | 0.609147 | 3 | 0 | 3 |
| CAPN15 | POLDIP2 | 0.606712 | 5 | 0 | 3 |
For details and further investigation, click here
