| Full name: WD repeat domain 24 | Alias Symbol: DKFZp434F054|JFP7 | ||
| Type: protein-coding gene | Cytoband: 16p13.3 | ||
| Entrez ID: 84219 | HGNC ID: HGNC:20852 | Ensembl Gene: ENSG00000127580 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
WDR24 involved pathways:
| KEGG pathway | Description | View |
|---|---|---|
| hsa04150 | mTOR signaling pathway |
Expression of WDR24:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | WDR24 | 84219 | 223293_at | 0.2964 | 0.6600 | |
| GSE26886 | WDR24 | 84219 | 223293_at | 0.2647 | 0.1651 | |
| GSE45670 | WDR24 | 84219 | 223293_at | 0.4474 | 0.0002 | |
| GSE53622 | WDR24 | 84219 | 23430 | 0.1899 | 0.0001 | |
| GSE53624 | WDR24 | 84219 | 23430 | 0.1734 | 0.0014 | |
| GSE63941 | WDR24 | 84219 | 223293_at | 0.8457 | 0.0182 | |
| GSE77861 | WDR24 | 84219 | 223293_at | 0.3149 | 0.1831 | |
| GSE97050 | WDR24 | 84219 | A_33_P3373850 | -0.0605 | 0.7898 | |
| SRP007169 | WDR24 | 84219 | RNAseq | -0.2479 | 0.5883 | |
| SRP064894 | WDR24 | 84219 | RNAseq | 0.5242 | 0.0108 | |
| SRP133303 | WDR24 | 84219 | RNAseq | -0.0724 | 0.6595 | |
| SRP159526 | WDR24 | 84219 | RNAseq | 0.2477 | 0.3520 | |
| SRP193095 | WDR24 | 84219 | RNAseq | 0.1196 | 0.1930 | |
| SRP219564 | WDR24 | 84219 | RNAseq | 0.3890 | 0.3059 | |
| TCGA | WDR24 | 84219 | RNAseq | -0.0152 | 0.7793 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by WDR24 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of WDR24:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | WDR24 | 84219 | 5 | 5 | 20 | |
| GSE20123 | WDR24 | 84219 | 5 | 4 | 21 | |
| GSE43470 | WDR24 | 84219 | 4 | 7 | 32 | |
| GSE46452 | WDR24 | 84219 | 38 | 1 | 20 | |
| GSE47630 | WDR24 | 84219 | 13 | 6 | 21 | |
| GSE54993 | WDR24 | 84219 | 3 | 5 | 62 | |
| GSE54994 | WDR24 | 84219 | 5 | 9 | 39 | |
| GSE60625 | WDR24 | 84219 | 4 | 0 | 7 | |
| GSE74703 | WDR24 | 84219 | 4 | 5 | 27 | |
| GSE74704 | WDR24 | 84219 | 3 | 2 | 15 | |
| TCGA | WDR24 | 84219 | 20 | 15 | 61 |
Total number of gains: 104; Total number of losses: 59; Total Number of normals: 325.
Somatic mutations of WDR24:
Generating mutation plots.
Highly correlated genes for WDR24:
Showing top 20/136 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| WDR24 | MRPL38 | 0.748393 | 3 | 0 | 3 |
| WDR24 | SPNS1 | 0.705863 | 3 | 0 | 3 |
| WDR24 | ZFPL1 | 0.678695 | 4 | 0 | 3 |
| WDR24 | OXLD1 | 0.677948 | 3 | 0 | 3 |
| WDR24 | ELK1 | 0.673342 | 4 | 0 | 3 |
| WDR24 | SLC12A9 | 0.671781 | 3 | 0 | 3 |
| WDR24 | C12orf10 | 0.662519 | 4 | 0 | 3 |
| WDR24 | CTPS2 | 0.661764 | 3 | 0 | 3 |
| WDR24 | MRPS34 | 0.660785 | 6 | 0 | 5 |
| WDR24 | YIF1A | 0.652565 | 3 | 0 | 3 |
| WDR24 | KCNJ9 | 0.651541 | 4 | 0 | 4 |
| WDR24 | MPV17L2 | 0.649547 | 4 | 0 | 4 |
| WDR24 | STUB1 | 0.645689 | 4 | 0 | 3 |
| WDR24 | SLC38A7 | 0.644618 | 5 | 0 | 4 |
| WDR24 | GLI4 | 0.631776 | 3 | 0 | 3 |
| WDR24 | CROCC | 0.627899 | 3 | 0 | 3 |
| WDR24 | CLCN7 | 0.619053 | 3 | 0 | 3 |
| WDR24 | MRPL12 | 0.618417 | 4 | 0 | 3 |
| WDR24 | NPRL3 | 0.617356 | 4 | 0 | 3 |
| WDR24 | ZC3HC1 | 0.61582 | 3 | 0 | 3 |
For details and further investigation, click here
