| Full name: coatomer protein complex subunit gamma 2 | Alias Symbol: 2-COP | ||
| Type: protein-coding gene | Cytoband: 7q32.2 | ||
| Entrez ID: 26958 | HGNC ID: HGNC:2237 | Ensembl Gene: ENSG00000158623 | OMIM ID: 604355 |
| Drug and gene relationship at DGIdb | |||
Expression of COPG2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | COPG2 | 26958 | 223457_at | -0.2693 | 0.5570 | |
| GSE26886 | COPG2 | 26958 | 223457_at | -0.2847 | 0.4110 | |
| GSE45670 | COPG2 | 26958 | 223457_at | 0.1507 | 0.6137 | |
| GSE53622 | COPG2 | 26958 | 51059 | -0.1603 | 0.0928 | |
| GSE53624 | COPG2 | 26958 | 51059 | 0.0339 | 0.6496 | |
| GSE63941 | COPG2 | 26958 | 223457_at | 0.1834 | 0.8068 | |
| GSE77861 | COPG2 | 26958 | 223457_at | -0.1640 | 0.2539 | |
| GSE97050 | COPG2 | 26958 | A_23_P61280 | 0.0924 | 0.6416 | |
| SRP007169 | COPG2 | 26958 | RNAseq | -0.7830 | 0.0143 | |
| SRP008496 | COPG2 | 26958 | RNAseq | -1.0414 | 0.0000 | |
| SRP064894 | COPG2 | 26958 | RNAseq | 0.0533 | 0.7989 | |
| SRP133303 | COPG2 | 26958 | RNAseq | -0.2225 | 0.1833 | |
| SRP159526 | COPG2 | 26958 | RNAseq | -0.0556 | 0.8778 | |
| SRP193095 | COPG2 | 26958 | RNAseq | -0.4243 | 0.0033 | |
| SRP219564 | COPG2 | 26958 | RNAseq | -0.2177 | 0.5899 | |
| TCGA | COPG2 | 26958 | RNAseq | 0.0687 | 0.4193 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by COPG2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of COPG2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | COPG2 | 26958 | 8 | 1 | 21 | |
| GSE20123 | COPG2 | 26958 | 8 | 1 | 21 | |
| GSE43470 | COPG2 | 26958 | 2 | 3 | 38 | |
| GSE46452 | COPG2 | 26958 | 7 | 2 | 50 | |
| GSE47630 | COPG2 | 26958 | 7 | 4 | 29 | |
| GSE54993 | COPG2 | 26958 | 3 | 5 | 62 | |
| GSE54994 | COPG2 | 26958 | 7 | 7 | 39 | |
| GSE60625 | COPG2 | 26958 | 0 | 0 | 11 | |
| GSE74703 | COPG2 | 26958 | 2 | 3 | 31 | |
| GSE74704 | COPG2 | 26958 | 4 | 1 | 15 | |
| TCGA | COPG2 | 26958 | 28 | 21 | 47 |
Total number of gains: 76; Total number of losses: 48; Total Number of normals: 364.
Somatic mutations of COPG2:
Generating mutation plots.
Highly correlated genes for COPG2:
Showing top 20/118 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| COPG2 | COG6 | 0.786755 | 3 | 0 | 3 |
| COPG2 | EEA1 | 0.786473 | 3 | 0 | 3 |
| COPG2 | APOBEC2 | 0.770995 | 3 | 0 | 3 |
| COPG2 | CCNYL1 | 0.768944 | 3 | 0 | 3 |
| COPG2 | STXBP5 | 0.758506 | 3 | 0 | 3 |
| COPG2 | FRMD4B | 0.753544 | 3 | 0 | 3 |
| COPG2 | TRIM5 | 0.741473 | 3 | 0 | 3 |
| COPG2 | STXBP3 | 0.73908 | 3 | 0 | 3 |
| COPG2 | MON1A | 0.734364 | 3 | 0 | 3 |
| COPG2 | C2CD2 | 0.727805 | 3 | 0 | 3 |
| COPG2 | TAOK3 | 0.717028 | 3 | 0 | 3 |
| COPG2 | RBKS | 0.716744 | 3 | 0 | 3 |
| COPG2 | C11orf54 | 0.708586 | 3 | 0 | 3 |
| COPG2 | ARPC3 | 0.708201 | 3 | 0 | 3 |
| COPG2 | SLC22A15 | 0.707231 | 3 | 0 | 3 |
| COPG2 | NDUFAF2 | 0.704107 | 3 | 0 | 3 |
| COPG2 | MRPL39 | 0.703623 | 4 | 0 | 3 |
| COPG2 | ELK3 | 0.699716 | 3 | 0 | 3 |
| COPG2 | LYSMD3 | 0.696544 | 3 | 0 | 3 |
| COPG2 | AHCYL2 | 0.694357 | 5 | 0 | 4 |
For details and further investigation, click here
