| Full name: ER membrane protein complex subunit 4 | Alias Symbol: FLJ90746|MGC24415|PIG17 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 51234 | HGNC ID: HGNC:28032 | Ensembl Gene: ENSG00000128463 | OMIM ID: 616245 |
Screen Evidence:
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Expression of EMC4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMC4 | 51234 | 223043_at | -0.3702 | 0.4619 | |
| GSE26886 | EMC4 | 51234 | 223857_x_at | -0.0212 | 0.9008 | |
| GSE45670 | EMC4 | 51234 | 223857_x_at | -0.2677 | 0.0155 | |
| GSE53622 | EMC4 | 51234 | 12900 | -0.1311 | 0.0190 | |
| GSE53624 | EMC4 | 51234 | 12900 | 0.0538 | 0.3175 | |
| GSE63941 | EMC4 | 51234 | 223043_at | 0.2318 | 0.5061 | |
| GSE77861 | EMC4 | 51234 | 223043_at | -0.3048 | 0.2413 | |
| SRP007169 | EMC4 | 51234 | RNAseq | -1.1556 | 0.0025 | |
| SRP008496 | EMC4 | 51234 | RNAseq | -1.1286 | 0.0000 | |
| SRP064894 | EMC4 | 51234 | RNAseq | -0.4332 | 0.0113 | |
| SRP133303 | EMC4 | 51234 | RNAseq | 0.0460 | 0.7370 | |
| SRP159526 | EMC4 | 51234 | RNAseq | -0.0977 | 0.6819 | |
| SRP193095 | EMC4 | 51234 | RNAseq | -0.2868 | 0.0557 | |
| SRP219564 | EMC4 | 51234 | RNAseq | -0.3634 | 0.0820 |
Upregulated datasets: 0; Downregulated datasets: 2.
Survival by EMC4 expression:
 |  |
| GSE53622 | GSE53624 |
Note: Click image to view full size file.
Copy number change of EMC4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMC4 | 51234 | 3 | 6 | 21 | |
| GSE20123 | EMC4 | 51234 | 3 | 6 | 21 | |
| GSE43470 | EMC4 | 51234 | 4 | 4 | 35 | |
| GSE46452 | EMC4 | 51234 | 3 | 7 | 49 | |
| GSE47630 | EMC4 | 51234 | 8 | 11 | 21 | |
| GSE54993 | EMC4 | 51234 | 4 | 6 | 60 | |
| GSE54994 | EMC4 | 51234 | 5 | 8 | 40 | |
| GSE60625 | EMC4 | 51234 | 4 | 0 | 7 | |
| GSE74703 | EMC4 | 51234 | 4 | 3 | 29 | |
| GSE74704 | EMC4 | 51234 | 2 | 5 | 13 | |
| TCGA | EMC4 | 51234 | 13 | 18 | 65 |
Total number of gains: 53; Total number of losses: 74; Total Number of normals: 361.
Somatic mutations of EMC4:
Generating mutation plots.
Highly correlated genes for EMC4:
Showing top 20/35 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMC4 | RPS17 | 0.698082 | 4 | 0 | 3 |
| EMC4 | WDR61 | 0.673483 | 4 | 0 | 4 |
| EMC4 | IMP3 | 0.655869 | 4 | 0 | 3 |
| EMC4 | OST4 | 0.653784 | 3 | 0 | 3 |
| EMC4 | COPS2 | 0.649837 | 5 | 0 | 4 |
| EMC4 | MRPL46 | 0.645273 | 4 | 0 | 3 |
| EMC4 | SRP14 | 0.632318 | 7 | 0 | 6 |
| EMC4 | OR7C1 | 0.631767 | 3 | 0 | 3 |
| EMC4 | AQR | 0.624653 | 6 | 0 | 5 |
| EMC4 | RSL24D1 | 0.622362 | 3 | 0 | 3 |
| EMC4 | KATNBL1 | 0.614036 | 5 | 0 | 4 |
| EMC4 | NOP10 | 0.611476 | 6 | 0 | 5 |
| EMC4 | MFAP1 | 0.611083 | 4 | 0 | 3 |
| EMC4 | LPCAT4 | 0.598787 | 5 | 0 | 4 |
| EMC4 | GTF2A2 | 0.59509 | 5 | 0 | 3 |
| EMC4 | PNN | 0.5948 | 4 | 0 | 3 |
| EMC4 | EIF3J | 0.58925 | 5 | 0 | 3 |
| EMC4 | EMC7 | 0.581189 | 7 | 0 | 5 |
| EMC4 | ARIH1 | 0.578759 | 4 | 0 | 3 |
| EMC4 | CCNDBP1 | 0.575962 | 5 | 0 | 3 |
For details and further investigation, click here
