| Full name: oligosaccharyltransferase complex subunit 4, non-catalytic | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 2p23.3 | ||
| Entrez ID: 100128731 | HGNC ID: HGNC:32483 | Ensembl Gene: ENSG00000228474 | OMIM ID: |
| Drug and gene relationship at DGIdb | |||
Expression of OST4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | OST4 | 100128731 | 224637_at | -0.0221 | 0.9592 | |
| GSE26886 | OST4 | 100128731 | 224637_at | 0.1686 | 0.3215 | |
| GSE45670 | OST4 | 100128731 | 224637_at | -0.1086 | 0.4723 | |
| GSE53622 | OST4 | 100128731 | 136298 | -0.2041 | 0.0001 | |
| GSE53624 | OST4 | 100128731 | 136298 | -0.2788 | 0.0000 | |
| GSE63941 | OST4 | 100128731 | 224637_at | -0.9414 | 0.0311 | |
| GSE77861 | OST4 | 100128731 | 224637_at | -0.2548 | 0.2855 | |
| GSE97050 | OST4 | 100128731 | A_32_P57854 | 0.0772 | 0.8823 | |
| SRP007169 | OST4 | 100128731 | RNAseq | -0.9764 | 0.0020 | |
| SRP008496 | OST4 | 100128731 | RNAseq | -0.7614 | 0.0000 | |
| SRP064894 | OST4 | 100128731 | RNAseq | 0.0723 | 0.8082 | |
| SRP133303 | OST4 | 100128731 | RNAseq | 0.1345 | 0.3386 | |
| SRP159526 | OST4 | 100128731 | RNAseq | -0.0855 | 0.6460 | |
| SRP193095 | OST4 | 100128731 | RNAseq | -0.6377 | 0.0001 | |
| SRP219564 | OST4 | 100128731 | RNAseq | -0.2926 | 0.2953 | |
| TCGA | OST4 | 100128731 | RNAseq | 0.0599 | 0.2665 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by OST4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of OST4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | OST4 | 100128731 | 11 | 2 | 17 | |
| GSE20123 | OST4 | 100128731 | 11 | 2 | 17 | |
| GSE43470 | OST4 | 100128731 | 3 | 1 | 39 | |
| GSE46452 | OST4 | 100128731 | 3 | 4 | 52 | |
| GSE47630 | OST4 | 100128731 | 8 | 0 | 32 | |
| GSE54993 | OST4 | 100128731 | 0 | 6 | 64 | |
| GSE54994 | OST4 | 100128731 | 10 | 0 | 43 | |
| GSE60625 | OST4 | 100128731 | 0 | 3 | 8 | |
| GSE74703 | OST4 | 100128731 | 3 | 0 | 33 | |
| GSE74704 | OST4 | 100128731 | 9 | 1 | 10 | |
| TCGA | OST4 | 100128731 | 37 | 2 | 57 |
Total number of gains: 95; Total number of losses: 21; Total Number of normals: 372.
Somatic mutations of OST4:
Generating mutation plots.
Highly correlated genes for OST4:
Showing top 20/53 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| OST4 | NDUFA4 | 0.698114 | 3 | 0 | 3 |
| OST4 | FLT4 | 0.684186 | 3 | 0 | 3 |
| OST4 | SCARB2 | 0.679704 | 3 | 0 | 3 |
| OST4 | PRELID1 | 0.661844 | 4 | 0 | 4 |
| OST4 | ZNF608 | 0.655939 | 3 | 0 | 3 |
| OST4 | EMC4 | 0.653784 | 3 | 0 | 3 |
| OST4 | CCDC92 | 0.635118 | 3 | 0 | 3 |
| OST4 | PNRC1 | 0.633005 | 3 | 0 | 3 |
| OST4 | TUBGCP2 | 0.626227 | 3 | 0 | 3 |
| OST4 | TMEM116 | 0.607835 | 3 | 0 | 3 |
| OST4 | KANK2 | 0.607668 | 3 | 0 | 3 |
| OST4 | PSMG2 | 0.607323 | 3 | 0 | 3 |
| OST4 | HNF1A | 0.604308 | 3 | 0 | 3 |
| OST4 | CDK14 | 0.603359 | 3 | 0 | 3 |
| OST4 | PCBP2 | 0.598549 | 3 | 0 | 3 |
| OST4 | RHOA | 0.596354 | 3 | 0 | 3 |
| OST4 | GPRC5B | 0.596163 | 3 | 0 | 3 |
| OST4 | AQR | 0.592393 | 3 | 0 | 3 |
| OST4 | LAMA4 | 0.591479 | 3 | 0 | 3 |
| OST4 | CELA3A | 0.589258 | 3 | 0 | 3 |
For details and further investigation, click here
