| Full name: lysophosphatidylcholine acyltransferase 4 | Alias Symbol: FLJ10257|LPAAT-eta|LPEAT2 | ||
| Type: protein-coding gene | Cytoband: 15q14 | ||
| Entrez ID: 254531 | HGNC ID: HGNC:30059 | Ensembl Gene: ENSG00000176454 | OMIM ID: 612039 |
Expression of LPCAT4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | LPCAT4 | 254531 | 40472_at | -0.3516 | 0.6730 | |
| GSE20347 | LPCAT4 | 254531 | 40472_at | -0.5853 | 0.0540 | |
| GSE23400 | LPCAT4 | 254531 | 213078_x_at | -0.3585 | 0.0000 | |
| GSE26886 | LPCAT4 | 254531 | 40472_at | -1.4520 | 0.0000 | |
| GSE29001 | LPCAT4 | 254531 | 40472_at | -0.5513 | 0.2730 | |
| GSE38129 | LPCAT4 | 254531 | 40472_at | -0.5161 | 0.0118 | |
| GSE45670 | LPCAT4 | 254531 | 40472_at | -0.4077 | 0.0686 | |
| GSE53622 | LPCAT4 | 254531 | 104734 | -0.5066 | 0.0001 | |
| GSE53624 | LPCAT4 | 254531 | 104734 | -0.4162 | 0.0000 | |
| GSE63941 | LPCAT4 | 254531 | 40472_at | 1.0569 | 0.0851 | |
| GSE77861 | LPCAT4 | 254531 | 40472_at | -0.3316 | 0.1071 | |
| GSE97050 | LPCAT4 | 254531 | A_23_P49009 | -0.2633 | 0.7561 | |
| SRP007169 | LPCAT4 | 254531 | RNAseq | -1.2223 | 0.0230 | |
| SRP008496 | LPCAT4 | 254531 | RNAseq | -1.3565 | 0.0003 | |
| SRP064894 | LPCAT4 | 254531 | RNAseq | -0.8185 | 0.0000 | |
| SRP133303 | LPCAT4 | 254531 | RNAseq | -0.8537 | 0.0000 | |
| SRP159526 | LPCAT4 | 254531 | RNAseq | -1.0104 | 0.0005 | |
| SRP193095 | LPCAT4 | 254531 | RNAseq | -0.7850 | 0.0000 | |
| SRP219564 | LPCAT4 | 254531 | RNAseq | -1.0814 | 0.0212 | |
| TCGA | LPCAT4 | 254531 | RNAseq | -0.1646 | 0.0144 |
Upregulated datasets: 0; Downregulated datasets: 5.
Survival by LPCAT4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of LPCAT4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | LPCAT4 | 254531 | 3 | 6 | 21 | |
| GSE20123 | LPCAT4 | 254531 | 3 | 6 | 21 | |
| GSE43470 | LPCAT4 | 254531 | 4 | 4 | 35 | |
| GSE46452 | LPCAT4 | 254531 | 3 | 7 | 49 | |
| GSE47630 | LPCAT4 | 254531 | 8 | 11 | 21 | |
| GSE54993 | LPCAT4 | 254531 | 4 | 6 | 60 | |
| GSE54994 | LPCAT4 | 254531 | 5 | 8 | 40 | |
| GSE60625 | LPCAT4 | 254531 | 4 | 0 | 7 | |
| GSE74703 | LPCAT4 | 254531 | 4 | 3 | 29 | |
| GSE74704 | LPCAT4 | 254531 | 2 | 5 | 13 | |
| TCGA | LPCAT4 | 254531 | 14 | 17 | 65 |
Total number of gains: 54; Total number of losses: 73; Total Number of normals: 361.
Somatic mutations of LPCAT4:
Generating mutation plots.
Highly correlated genes for LPCAT4:
Showing top 20/722 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| LPCAT4 | THAP2 | 0.744275 | 3 | 0 | 3 |
| LPCAT4 | RAB8A | 0.73253 | 4 | 0 | 3 |
| LPCAT4 | ZNF436 | 0.709008 | 4 | 0 | 4 |
| LPCAT4 | FRMD6 | 0.701277 | 3 | 0 | 3 |
| LPCAT4 | CLTA | 0.697038 | 3 | 0 | 3 |
| LPCAT4 | TRIM6 | 0.696166 | 5 | 0 | 4 |
| LPCAT4 | FAM83D | 0.692339 | 4 | 0 | 4 |
| LPCAT4 | TMEM41B | 0.68598 | 5 | 0 | 3 |
| LPCAT4 | NFIA | 0.684712 | 3 | 0 | 3 |
| LPCAT4 | SRRM1 | 0.684406 | 4 | 0 | 3 |
| LPCAT4 | PKIA | 0.677747 | 3 | 0 | 3 |
| LPCAT4 | PRPF38A | 0.677703 | 4 | 0 | 3 |
| LPCAT4 | ESYT2 | 0.676064 | 4 | 0 | 4 |
| LPCAT4 | ZDHHC6 | 0.668465 | 4 | 0 | 4 |
| LPCAT4 | C5orf51 | 0.666448 | 3 | 0 | 3 |
| LPCAT4 | CIB1 | 0.665509 | 6 | 0 | 6 |
| LPCAT4 | ZNRF1 | 0.664086 | 3 | 0 | 3 |
| LPCAT4 | KIF21A | 0.659108 | 5 | 0 | 4 |
| LPCAT4 | WIPF2 | 0.658219 | 3 | 0 | 3 |
| LPCAT4 | ACTR2 | 0.658189 | 4 | 0 | 3 |
For details and further investigation, click here
