| Full name: general transcription factor IIA subunit 2 | Alias Symbol: TFIIA|HsT18745 | ||
| Type: protein-coding gene | Cytoband: 15q22.2 | ||
| Entrez ID: 2958 | HGNC ID: HGNC:4647 | Ensembl Gene: ENSG00000140307 | OMIM ID: 600519 |
| Drug and gene relationship at DGIdb | |||
Expression of GTF2A2:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | GTF2A2 | 2958 | 202678_at | -0.1545 | 0.7369 | |
| GSE20347 | GTF2A2 | 2958 | 202678_at | 0.1113 | 0.5909 | |
| GSE23400 | GTF2A2 | 2958 | 202678_at | 0.0932 | 0.1781 | |
| GSE26886 | GTF2A2 | 2958 | 202678_at | 0.0334 | 0.8858 | |
| GSE29001 | GTF2A2 | 2958 | 202678_at | -0.0270 | 0.9483 | |
| GSE38129 | GTF2A2 | 2958 | 202678_at | 0.2410 | 0.0520 | |
| GSE45670 | GTF2A2 | 2958 | 202678_at | 0.1165 | 0.4659 | |
| GSE53622 | GTF2A2 | 2958 | 2253 | 0.0906 | 0.1262 | |
| GSE53624 | GTF2A2 | 2958 | 3530 | 0.1236 | 0.0112 | |
| GSE63941 | GTF2A2 | 2958 | 202678_at | 0.0281 | 0.9522 | |
| GSE77861 | GTF2A2 | 2958 | 202678_at | 0.1578 | 0.6186 | |
| GSE97050 | GTF2A2 | 2958 | A_24_P270525 | -0.1521 | 0.5506 | |
| SRP007169 | GTF2A2 | 2958 | RNAseq | -0.4655 | 0.3129 | |
| SRP008496 | GTF2A2 | 2958 | RNAseq | -0.3436 | 0.2236 | |
| SRP064894 | GTF2A2 | 2958 | RNAseq | -0.1631 | 0.3245 | |
| SRP133303 | GTF2A2 | 2958 | RNAseq | 0.3113 | 0.0610 | |
| SRP159526 | GTF2A2 | 2958 | RNAseq | -0.2051 | 0.5338 | |
| SRP193095 | GTF2A2 | 2958 | RNAseq | -0.1514 | 0.2506 | |
| SRP219564 | GTF2A2 | 2958 | RNAseq | -0.4514 | 0.0322 | |
| TCGA | GTF2A2 | 2958 | RNAseq | 0.1051 | 0.0647 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by GTF2A2 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of GTF2A2:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | GTF2A2 | 2958 | 6 | 4 | 20 | |
| GSE20123 | GTF2A2 | 2958 | 6 | 3 | 21 | |
| GSE43470 | GTF2A2 | 2958 | 4 | 4 | 35 | |
| GSE46452 | GTF2A2 | 2958 | 3 | 7 | 49 | |
| GSE47630 | GTF2A2 | 2958 | 8 | 10 | 22 | |
| GSE54993 | GTF2A2 | 2958 | 5 | 6 | 59 | |
| GSE54994 | GTF2A2 | 2958 | 6 | 8 | 39 | |
| GSE60625 | GTF2A2 | 2958 | 4 | 0 | 7 | |
| GSE74703 | GTF2A2 | 2958 | 4 | 3 | 29 | |
| GSE74704 | GTF2A2 | 2958 | 2 | 3 | 15 | |
| TCGA | GTF2A2 | 2958 | 10 | 17 | 69 |
Total number of gains: 58; Total number of losses: 65; Total Number of normals: 365.
Somatic mutations of GTF2A2:
Generating mutation plots.
Highly correlated genes for GTF2A2:
Showing top 20/336 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| GTF2A2 | IPO7 | 0.7709 | 3 | 0 | 3 |
| GTF2A2 | RHBDD1 | 0.752001 | 3 | 0 | 3 |
| GTF2A2 | INSIG1 | 0.748997 | 3 | 0 | 3 |
| GTF2A2 | LRIG3 | 0.731512 | 3 | 0 | 3 |
| GTF2A2 | RASSF9 | 0.716656 | 3 | 0 | 3 |
| GTF2A2 | SGMS1 | 0.714087 | 3 | 0 | 3 |
| GTF2A2 | EIF1AX | 0.713581 | 3 | 0 | 3 |
| GTF2A2 | COQ3 | 0.707181 | 3 | 0 | 3 |
| GTF2A2 | XK | 0.704356 | 3 | 0 | 3 |
| GTF2A2 | PLEKHB2 | 0.703692 | 3 | 0 | 3 |
| GTF2A2 | TFPI | 0.702063 | 3 | 0 | 3 |
| GTF2A2 | SAP18 | 0.693211 | 3 | 0 | 3 |
| GTF2A2 | RGS10 | 0.690902 | 3 | 0 | 3 |
| GTF2A2 | ZZZ3 | 0.68761 | 3 | 0 | 3 |
| GTF2A2 | RPP14 | 0.683158 | 3 | 0 | 3 |
| GTF2A2 | MCU | 0.680601 | 3 | 0 | 3 |
| GTF2A2 | SEC11C | 0.678223 | 3 | 0 | 3 |
| GTF2A2 | ALKBH7 | 0.676758 | 3 | 0 | 3 |
| GTF2A2 | TMEM126A | 0.67335 | 3 | 0 | 3 |
| GTF2A2 | UGP2 | 0.669245 | 4 | 0 | 3 |
For details and further investigation, click here
