| Full name: IMP U3 small nucleolar ribonucleoprotein 3 | Alias Symbol: FLJ10968|BRMS2 | ||
| Type: protein-coding gene | Cytoband: 15q24.2 | ||
| Entrez ID: 55272 | HGNC ID: HGNC:14497 | Ensembl Gene: ENSG00000177971 | OMIM ID: 612980 |
| Drug and gene relationship at DGIdb | |||
Expression of IMP3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | IMP3 | 55272 | 221688_s_at | 0.0697 | 0.9381 | |
| GSE20347 | IMP3 | 55272 | 221688_s_at | -0.1634 | 0.4267 | |
| GSE23400 | IMP3 | 55272 | 221688_s_at | 0.0187 | 0.8426 | |
| GSE26886 | IMP3 | 55272 | 221688_s_at | 0.0361 | 0.8900 | |
| GSE29001 | IMP3 | 55272 | 221688_s_at | 0.0432 | 0.8732 | |
| GSE38129 | IMP3 | 55272 | 221688_s_at | 0.1280 | 0.4713 | |
| GSE45670 | IMP3 | 55272 | 221688_s_at | -0.0400 | 0.7617 | |
| GSE53622 | IMP3 | 55272 | 51828 | -0.3004 | 0.0008 | |
| GSE53624 | IMP3 | 55272 | 51828 | -0.3956 | 0.0000 | |
| GSE63941 | IMP3 | 55272 | 221688_s_at | 0.5618 | 0.1654 | |
| GSE77861 | IMP3 | 55272 | 221688_s_at | -0.1476 | 0.6074 | |
| GSE97050 | IMP3 | 55272 | A_23_P33809 | -0.1477 | 0.7288 | |
| SRP007169 | IMP3 | 55272 | RNAseq | -0.8407 | 0.0378 | |
| SRP008496 | IMP3 | 55272 | RNAseq | -0.8856 | 0.0025 | |
| SRP064894 | IMP3 | 55272 | RNAseq | -0.3343 | 0.1763 | |
| SRP133303 | IMP3 | 55272 | RNAseq | -0.3590 | 0.1068 | |
| SRP159526 | IMP3 | 55272 | RNAseq | -0.3550 | 0.0488 | |
| SRP193095 | IMP3 | 55272 | RNAseq | -0.5416 | 0.0000 | |
| SRP219564 | IMP3 | 55272 | RNAseq | -0.0451 | 0.9211 | |
| TCGA | IMP3 | 55272 | RNAseq | 0.0335 | 0.5378 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by IMP3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of IMP3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | IMP3 | 55272 | 8 | 1 | 21 | |
| GSE20123 | IMP3 | 55272 | 8 | 1 | 21 | |
| GSE43470 | IMP3 | 55272 | 4 | 6 | 33 | |
| GSE46452 | IMP3 | 55272 | 3 | 7 | 49 | |
| GSE47630 | IMP3 | 55272 | 8 | 10 | 22 | |
| GSE54993 | IMP3 | 55272 | 5 | 6 | 59 | |
| GSE54994 | IMP3 | 55272 | 5 | 6 | 42 | |
| GSE60625 | IMP3 | 55272 | 4 | 0 | 7 | |
| GSE74703 | IMP3 | 55272 | 4 | 3 | 29 | |
| GSE74704 | IMP3 | 55272 | 4 | 1 | 15 | |
| TCGA | IMP3 | 55272 | 14 | 15 | 67 |
Total number of gains: 67; Total number of losses: 56; Total Number of normals: 365.
Somatic mutations of IMP3:
Generating mutation plots.
Highly correlated genes for IMP3:
Showing top 20/460 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| IMP3 | SWAP70 | 0.767206 | 3 | 0 | 3 |
| IMP3 | YLPM1 | 0.754557 | 3 | 0 | 3 |
| IMP3 | CAPN2 | 0.735767 | 3 | 0 | 3 |
| IMP3 | ZNF543 | 0.725227 | 3 | 0 | 3 |
| IMP3 | ZDHHC6 | 0.719579 | 3 | 0 | 3 |
| IMP3 | RPS3 | 0.711626 | 3 | 0 | 3 |
| IMP3 | GSR | 0.709271 | 3 | 0 | 3 |
| IMP3 | PLD2 | 0.707638 | 3 | 0 | 3 |
| IMP3 | TMEM54 | 0.702976 | 3 | 0 | 3 |
| IMP3 | MAP3K1 | 0.698037 | 3 | 0 | 3 |
| IMP3 | SCAMP2 | 0.693415 | 5 | 0 | 4 |
| IMP3 | PRPF38A | 0.692197 | 3 | 0 | 3 |
| IMP3 | PI4K2B | 0.686611 | 3 | 0 | 3 |
| IMP3 | NAGK | 0.686017 | 3 | 0 | 3 |
| IMP3 | GTF3C2 | 0.68443 | 4 | 0 | 4 |
| IMP3 | LETMD1 | 0.684309 | 3 | 0 | 3 |
| IMP3 | MRPS11 | 0.683248 | 9 | 0 | 7 |
| IMP3 | CCDC12 | 0.679331 | 3 | 0 | 3 |
| IMP3 | LRBA | 0.675996 | 4 | 0 | 4 |
| IMP3 | FDXACB1 | 0.668121 | 3 | 0 | 3 |
For details and further investigation, click here
