| Full name: EMG1 N1-specific pseudouridine methyltransferase | Alias Symbol: C2F|NEP1|Grcc2f | ||
| Type: protein-coding gene | Cytoband: 12p13.31 | ||
| Entrez ID: 10436 | HGNC ID: HGNC:16912 | Ensembl Gene: ENSG00000126749 | OMIM ID: 611531 |
| Drug and gene relationship at DGIdb | |||
Expression of EMG1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | EMG1 | 10436 | 209233_at | 0.5484 | 0.2037 | |
| GSE20347 | EMG1 | 10436 | 209233_at | 0.7085 | 0.0012 | |
| GSE23400 | EMG1 | 10436 | 209233_at | 0.7200 | 0.0000 | |
| GSE26886 | EMG1 | 10436 | 209233_at | 0.2207 | 0.4499 | |
| GSE29001 | EMG1 | 10436 | 209233_at | 0.8347 | 0.1233 | |
| GSE38129 | EMG1 | 10436 | 209233_at | 0.6712 | 0.0000 | |
| GSE45670 | EMG1 | 10436 | 209233_at | 0.6267 | 0.0030 | |
| GSE63941 | EMG1 | 10436 | 209233_at | 0.7571 | 0.1693 | |
| GSE77861 | EMG1 | 10436 | 209233_at | 0.7445 | 0.0282 | |
| GSE97050 | EMG1 | 10436 | A_24_P253215 | 0.4251 | 0.2199 | |
| SRP007169 | EMG1 | 10436 | RNAseq | 1.5308 | 0.0086 | |
| SRP008496 | EMG1 | 10436 | RNAseq | 1.2404 | 0.0115 | |
| SRP064894 | EMG1 | 10436 | RNAseq | 0.2028 | 0.3047 | |
| SRP133303 | EMG1 | 10436 | RNAseq | 0.5624 | 0.0032 | |
| SRP159526 | EMG1 | 10436 | RNAseq | 0.1081 | 0.6695 | |
| SRP193095 | EMG1 | 10436 | RNAseq | 0.3077 | 0.0036 | |
| SRP219564 | EMG1 | 10436 | RNAseq | 0.3001 | 0.2525 | |
| TCGA | EMG1 | 10436 | RNAseq | 0.2954 | 0.0000 |
Upregulated datasets: 2; Downregulated datasets: 0.
Survival by EMG1 expression:
 |
| TCGA |
Note: Click image to view full size file.
Copy number change of EMG1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | EMG1 | 10436 | 9 | 3 | 18 | |
| GSE20123 | EMG1 | 10436 | 9 | 3 | 18 | |
| GSE43470 | EMG1 | 10436 | 8 | 3 | 32 | |
| GSE46452 | EMG1 | 10436 | 10 | 1 | 48 | |
| GSE47630 | EMG1 | 10436 | 12 | 2 | 26 | |
| GSE54993 | EMG1 | 10436 | 1 | 10 | 59 | |
| GSE54994 | EMG1 | 10436 | 10 | 2 | 41 | |
| GSE60625 | EMG1 | 10436 | 0 | 1 | 10 | |
| GSE74703 | EMG1 | 10436 | 7 | 2 | 27 | |
| GSE74704 | EMG1 | 10436 | 5 | 3 | 12 | |
| TCGA | EMG1 | 10436 | 40 | 6 | 50 |
Total number of gains: 111; Total number of losses: 36; Total Number of normals: 341.
Somatic mutations of EMG1:
Generating mutation plots.
Highly correlated genes for EMG1:
Showing top 20/1628 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| EMG1 | SPNS1 | 0.80055 | 3 | 0 | 3 |
| EMG1 | CENPW | 0.786063 | 4 | 0 | 4 |
| EMG1 | DDX55 | 0.774746 | 3 | 0 | 3 |
| EMG1 | QSOX2 | 0.769693 | 3 | 0 | 3 |
| EMG1 | NUS1 | 0.75974 | 3 | 0 | 3 |
| EMG1 | ATM | 0.759077 | 3 | 0 | 3 |
| EMG1 | NCAPD2 | 0.757341 | 11 | 0 | 11 |
| EMG1 | PHB2 | 0.754204 | 11 | 0 | 11 |
| EMG1 | STPG1 | 0.7542 | 3 | 0 | 3 |
| EMG1 | SLC30A7 | 0.75334 | 3 | 0 | 3 |
| EMG1 | SENP1 | 0.752713 | 3 | 0 | 3 |
| EMG1 | TMEM216 | 0.751365 | 3 | 0 | 3 |
| EMG1 | FOXM1 | 0.749753 | 9 | 0 | 9 |
| EMG1 | CDCA3 | 0.749126 | 11 | 0 | 10 |
| EMG1 | TUBG1 | 0.747849 | 8 | 0 | 8 |
| EMG1 | WDR92 | 0.74778 | 3 | 0 | 3 |
| EMG1 | LRRC8B | 0.746809 | 4 | 0 | 3 |
| EMG1 | MRPL51 | 0.74597 | 7 | 0 | 7 |
| EMG1 | KLHL7 | 0.742678 | 6 | 0 | 5 |
| EMG1 | STOML1 | 0.741352 | 3 | 0 | 3 |
For details and further investigation, click here
