| Full name: centromere protein W | Alias Symbol: CUG2 | ||
| Type: protein-coding gene | Cytoband: 6q22.32 | ||
| Entrez ID: 387103 | HGNC ID: HGNC:21488 | Ensembl Gene: ENSG00000203760 | OMIM ID: 611264 |
| Drug and gene relationship at DGIdb | |||
Expression of CENPW:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | CENPW | 387103 | 226936_at | 0.7832 | 0.0893 | |
| GSE26886 | CENPW | 387103 | 226936_at | 1.3959 | 0.0000 | |
| GSE45670 | CENPW | 387103 | 226936_at | 1.1866 | 0.0000 | |
| GSE53622 | CENPW | 387103 | 20134 | 1.2181 | 0.0000 | |
| GSE53624 | CENPW | 387103 | 20134 | 1.5294 | 0.0000 | |
| GSE63941 | CENPW | 387103 | 226936_at | 1.4724 | 0.0160 | |
| GSE77861 | CENPW | 387103 | 226936_at | 0.4015 | 0.1882 | |
| GSE97050 | CENPW | 387103 | A_24_P462899 | 1.3242 | 0.1453 | |
| SRP007169 | CENPW | 387103 | RNAseq | 1.2898 | 0.0075 | |
| SRP008496 | CENPW | 387103 | RNAseq | 1.1699 | 0.0009 | |
| SRP064894 | CENPW | 387103 | RNAseq | 1.4334 | 0.0000 | |
| SRP133303 | CENPW | 387103 | RNAseq | 1.2543 | 0.0000 | |
| SRP159526 | CENPW | 387103 | RNAseq | 1.0502 | 0.0003 | |
| SRP193095 | CENPW | 387103 | RNAseq | 0.7338 | 0.0004 | |
| SRP219564 | CENPW | 387103 | RNAseq | 0.7546 | 0.1147 | |
| TCGA | CENPW | 387103 | RNAseq | 1.2121 | 0.0000 |
Upregulated datasets: 11; Downregulated datasets: 0.
Survival by CENPW expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of CENPW:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | CENPW | 387103 | 1 | 4 | 25 | |
| GSE20123 | CENPW | 387103 | 2 | 3 | 25 | |
| GSE43470 | CENPW | 387103 | 5 | 0 | 38 | |
| GSE46452 | CENPW | 387103 | 2 | 11 | 46 | |
| GSE47630 | CENPW | 387103 | 9 | 4 | 27 | |
| GSE54993 | CENPW | 387103 | 4 | 2 | 64 | |
| GSE54994 | CENPW | 387103 | 8 | 8 | 37 | |
| GSE60625 | CENPW | 387103 | 0 | 1 | 10 | |
| GSE74703 | CENPW | 387103 | 4 | 0 | 32 | |
| GSE74704 | CENPW | 387103 | 0 | 1 | 19 | |
| TCGA | CENPW | 387103 | 11 | 18 | 67 |
Total number of gains: 46; Total number of losses: 52; Total Number of normals: 390.
Somatic mutations of CENPW:
Generating mutation plots.
Highly correlated genes for CENPW:
Showing top 20/1689 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| CENPW | MYBL2 | 0.831776 | 7 | 0 | 7 |
| CENPW | ZWILCH | 0.819697 | 7 | 0 | 7 |
| CENPW | CEP55 | 0.815678 | 7 | 0 | 7 |
| CENPW | UBE2T | 0.81403 | 8 | 0 | 8 |
| CENPW | CENPN | 0.800715 | 8 | 0 | 8 |
| CENPW | CCNB2 | 0.795867 | 7 | 0 | 7 |
| CENPW | PRC1 | 0.795794 | 8 | 0 | 8 |
| CENPW | KNSTRN | 0.79437 | 7 | 0 | 7 |
| CENPW | MTFR2 | 0.791649 | 7 | 0 | 7 |
| CENPW | MTHFD1L | 0.789967 | 3 | 0 | 3 |
| CENPW | SPAG5 | 0.786589 | 8 | 0 | 8 |
| CENPW | TTK | 0.786364 | 8 | 0 | 8 |
| CENPW | EMG1 | 0.786063 | 4 | 0 | 4 |
| CENPW | ZWINT | 0.786034 | 6 | 0 | 6 |
| CENPW | CDC45 | 0.784661 | 8 | 0 | 8 |
| CENPW | KIF23 | 0.783863 | 8 | 0 | 7 |
| CENPW | BLM | 0.783163 | 8 | 0 | 8 |
| CENPW | FANCI | 0.782265 | 8 | 0 | 8 |
| CENPW | CKS1B | 0.779631 | 8 | 0 | 8 |
| CENPW | TK1 | 0.778606 | 6 | 0 | 6 |
For details and further investigation, click here
