NCAPD2

 

Full name: non-SMC condensin I complex subunit D2 Alias Symbol: CNAP1|hCAP-D2|CAP-D2|KIAA0159
Type: protein-coding gene Cytoband: 12p13.31
Entrez ID: 9918 HGNC ID: HGNC:24305 Ensembl Gene: ENSG00000010292 OMIM ID: 615638
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of NCAPD2:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 NCAPD2 9918 201774_s_at 1.1076 0.1165
GSE20347 NCAPD2 9918 201774_s_at 1.0230 0.0000
GSE23400 NCAPD2 9918 201774_s_at 0.9814 0.0000
GSE26886 NCAPD2 9918 201774_s_at 0.8365 0.0181
GSE29001 NCAPD2 9918 201774_s_at 1.2877 0.0037
GSE38129 NCAPD2 9918 201774_s_at 1.1700 0.0000
GSE45670 NCAPD2 9918 201774_s_at 0.9263 0.0015
GSE53622 NCAPD2 9918 59464 1.0817 0.0000
GSE53624 NCAPD2 9918 27833 0.9640 0.0000
GSE63941 NCAPD2 9918 201774_s_at 1.9795 0.0043
GSE77861 NCAPD2 9918 201774_s_at 1.1587 0.0068
GSE97050 NCAPD2 9918 A_33_P3303385 0.6589 0.1440
SRP007169 NCAPD2 9918 RNAseq 2.2675 0.0000
SRP008496 NCAPD2 9918 RNAseq 1.7833 0.0000
SRP064894 NCAPD2 9918 RNAseq 0.7556 0.0002
SRP133303 NCAPD2 9918 RNAseq 1.1652 0.0000
SRP159526 NCAPD2 9918 RNAseq 1.1081 0.0000
SRP193095 NCAPD2 9918 RNAseq 0.8077 0.0000
SRP219564 NCAPD2 9918 RNAseq 0.8023 0.0242
TCGA NCAPD2 9918 RNAseq 0.4203 0.0000

Upregulated datasets: 10; Downregulated datasets: 0.  

 

Survival by NCAPD2 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of NCAPD2:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 NCAPD2 9918 9 4 17
GSE20123 NCAPD2 9918 9 4 17
GSE43470 NCAPD2 9918 8 3 32
GSE46452 NCAPD2 9918 10 1 48
GSE47630 NCAPD2 9918 12 2 26
GSE54993 NCAPD2 9918 1 10 59
GSE54994 NCAPD2 9918 10 2 41
GSE60625 NCAPD2 9918 0 1 10
GSE74703 NCAPD2 9918 7 2 27
GSE74704 NCAPD2 9918 5 3 12
TCGA NCAPD2 9918 40 6 50

Total number of gains: 111; Total number of losses: 38; Total Number of normals: 339.  

 

Somatic mutations of NCAPD2:

 

Generating mutation plots.

 

Highly correlated genes for NCAPD2:

 

Showing top 20/1891 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
NCAPD2RAD51AP10.83094912012
NCAPD2CDCA30.82006313013
NCAPD2FOXM10.8071412011
NCAPD2KIAA15220.782191303
NCAPD2MCM60.77329513012
NCAPD2CCNB20.77260812012
NCAPD2UBE2T0.769163909
NCAPD2MCM20.76886512012
NCAPD2TPX20.76475513013
NCAPD2PTCD10.764595303
NCAPD2SPAG50.7638913013
NCAPD2TIMELESS0.76368213013
NCAPD2BLM0.76303712012
NCAPD2CEP550.75810913013
NCAPD2EMG10.75734111011
NCAPD2NCAPG20.7541812011
NCAPD2NUSAP10.75394513011
NCAPD2NOP20.75391512012
NCAPD2NEK20.75342313012
NCAPD2EPS80.750783303

For details and further investigation, click here