FOXM1

 

Full name: forkhead box M1 Alias Symbol: HFH-11|trident|HNF-3|INS-1|MPP2|MPHOSPH2|TGT3
Type: protein-coding gene Cytoband: 12p13.33
Entrez ID: 2305 HGNC ID: HGNC:3818 Ensembl Gene: ENSG00000111206 OMIM ID: 602341
Drug and gene relationship at DGIdb
Screen Evidence:

 

Expression of FOXM1:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 FOXM1 2305 202580_x_at 1.9297 0.0264
GSE20347 FOXM1 2305 202580_x_at 1.7968 0.0000
GSE23400 FOXM1 2305 202580_x_at 1.6646 0.0000
GSE26886 FOXM1 2305 202580_x_at 1.0490 0.0090
GSE29001 FOXM1 2305 202580_x_at 1.6957 0.0000
GSE38129 FOXM1 2305 202580_x_at 2.0271 0.0000
GSE45670 FOXM1 2305 202580_x_at 1.7768 0.0000
GSE53622 FOXM1 2305 3509 2.0888 0.0000
GSE53624 FOXM1 2305 3509 1.8359 0.0000
GSE63941 FOXM1 2305 202580_x_at 1.8183 0.0089
GSE77861 FOXM1 2305 202580_x_at 1.3724 0.0019
GSE97050 FOXM1 2305 A_23_P151150 1.1411 0.1403
SRP007169 FOXM1 2305 RNAseq 3.8268 0.0000
SRP008496 FOXM1 2305 RNAseq 3.1973 0.0000
SRP064894 FOXM1 2305 RNAseq 1.8119 0.0000
SRP133303 FOXM1 2305 RNAseq 1.6635 0.0000
SRP159526 FOXM1 2305 RNAseq 2.1460 0.0000
SRP193095 FOXM1 2305 RNAseq 1.3271 0.0000
SRP219564 FOXM1 2305 RNAseq 1.8229 0.0002
TCGA FOXM1 2305 RNAseq 1.0362 0.0000

Upregulated datasets: 19; Downregulated datasets: 0.  

 

Survival by FOXM1 expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of FOXM1:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 FOXM1 2305 6 4 20
GSE20123 FOXM1 2305 6 4 20
GSE43470 FOXM1 2305 11 4 28
GSE46452 FOXM1 2305 10 1 48
GSE47630 FOXM1 2305 12 2 26
GSE54993 FOXM1 2305 1 10 59
GSE54994 FOXM1 2305 10 2 41
GSE60625 FOXM1 2305 0 1 10
GSE74703 FOXM1 2305 11 2 23
GSE74704 FOXM1 2305 4 2 14
TCGA FOXM1 2305 40 6 50

Total number of gains: 111; Total number of losses: 38; Total Number of normals: 339.  

 

Somatic mutations of FOXM1:

 

Generating mutation plots.

 

Highly correlated genes for FOXM1:

 

Showing top 20/1963 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
FOXM1RAD51AP10.88139913012
FOXM1BUB10.877207909
FOXM1CDCA30.86654712012
FOXM1KIF18B0.86466911011
FOXM1NCAPH0.851908909
FOXM1CDK10.84323412012
FOXM1MCM20.83281913012
FOXM1CDC450.83024812012
FOXM1AURKB0.82986313013
FOXM1STIL0.82845612012
FOXM1TPX20.82738113012
FOXM1DLGAP50.82510712012
FOXM1KIF140.8246913013
FOXM1ECT20.81770113012
FOXM1FEN10.817711011
FOXM1MYBL20.81758812012
FOXM1CENPF0.81622313012
FOXM1CENPN0.81597612012
FOXM1NEK20.81274113013
FOXM1SPAG50.80918713012

For details and further investigation, click here