| Full name: enamelin | Alias Symbol: | ||
| Type: protein-coding gene | Cytoband: 4q13.3 | ||
| Entrez ID: 10117 | HGNC ID: HGNC:3344 | Ensembl Gene: ENSG00000132464 | OMIM ID: 606585 |
| Drug and gene relationship at DGIdb | |||
Expression of ENAM:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ENAM | 10117 | 223893_at | -0.0510 | 0.8641 | |
| GSE26886 | ENAM | 10117 | 223893_at | -0.0486 | 0.7212 | |
| GSE45670 | ENAM | 10117 | 223893_at | -0.0542 | 0.5947 | |
| GSE53622 | ENAM | 10117 | 37603 | -0.5002 | 0.0034 | |
| GSE53624 | ENAM | 10117 | 37603 | -0.2765 | 0.0131 | |
| GSE63941 | ENAM | 10117 | 223893_at | 0.0122 | 0.9316 | |
| GSE77861 | ENAM | 10117 | 223893_at | 0.0037 | 0.9858 | |
| TCGA | ENAM | 10117 | RNAseq | -3.8020 | 0.0000 |
Upregulated datasets: 0; Downregulated datasets: 1.
Survival by ENAM expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ENAM:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ENAM | 10117 | 0 | 11 | 19 | |
| GSE20123 | ENAM | 10117 | 0 | 11 | 19 | |
| GSE43470 | ENAM | 10117 | 0 | 13 | 30 | |
| GSE46452 | ENAM | 10117 | 2 | 35 | 22 | |
| GSE47630 | ENAM | 10117 | 1 | 19 | 20 | |
| GSE54993 | ENAM | 10117 | 7 | 0 | 63 | |
| GSE54994 | ENAM | 10117 | 1 | 9 | 43 | |
| GSE60625 | ENAM | 10117 | 0 | 0 | 11 | |
| GSE74703 | ENAM | 10117 | 0 | 11 | 25 | |
| GSE74704 | ENAM | 10117 | 0 | 6 | 14 | |
| TCGA | ENAM | 10117 | 16 | 28 | 52 |
Total number of gains: 27; Total number of losses: 143; Total Number of normals: 318.
Somatic mutations of ENAM:
Generating mutation plots.
Highly correlated genes for ENAM:
Showing top 20/40 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ENAM | NPPA | 0.735579 | 3 | 0 | 3 |
| ENAM | INSM2 | 0.726118 | 3 | 0 | 3 |
| ENAM | KLHL41 | 0.672454 | 3 | 0 | 3 |
| ENAM | VIPR2 | 0.646921 | 4 | 0 | 3 |
| ENAM | ITIH2 | 0.640717 | 3 | 0 | 3 |
| ENAM | PHYH | 0.631896 | 3 | 0 | 3 |
| ENAM | NEUROD6 | 0.616727 | 3 | 0 | 3 |
| ENAM | SLC17A4 | 0.610906 | 3 | 0 | 3 |
| ENAM | SYT2 | 0.61088 | 4 | 0 | 3 |
| ENAM | OLAH | 0.605152 | 4 | 0 | 3 |
| ENAM | HNF1B | 0.60318 | 4 | 0 | 3 |
| ENAM | PNPLA2 | 0.600597 | 3 | 0 | 3 |
| ENAM | ZNF747 | 0.598774 | 3 | 0 | 3 |
| ENAM | ESRRG | 0.59871 | 4 | 0 | 3 |
| ENAM | PIGQ | 0.596891 | 4 | 0 | 3 |
| ENAM | TTR | 0.590331 | 5 | 0 | 3 |
| ENAM | MPZ | 0.579371 | 3 | 0 | 3 |
| ENAM | LGI4 | 0.576696 | 4 | 0 | 3 |
| ENAM | FGF16 | 0.57565 | 3 | 0 | 3 |
| ENAM | ADAL | 0.575527 | 4 | 0 | 3 |
For details and further investigation, click here
