ADAL

 

Full name: adenosine deaminase like Alias Symbol: 
Type: protein-coding gene Cytoband: 15q15.3
Entrez ID: 161823 HGNC ID: HGNC:31853 Ensembl Gene: ENSG00000168803 OMIM ID: 
Drug and gene relationship at DGIdb

 

Expression of ADAL:

 

Dataset Gene EntrezID Probe Log2FC Adj.pValue Expression
GSE17351 ADAL 161823 238424_at -0.2121 0.4612
GSE26886 ADAL 161823 238424_at -0.0275 0.8867
GSE45670 ADAL 161823 238424_at 0.0134 0.9383
GSE53622 ADAL 161823 14582 -0.9852 0.0000
GSE53624 ADAL 161823 14582 -0.6793 0.0000
GSE63941 ADAL 161823 238424_at -0.0515 0.9010
GSE77861 ADAL 161823 238424_at -0.2009 0.0682
GSE97050 ADAL A_21_P0000021 -0.2803 0.4101
SRP007169 ADAL 161823 RNAseq 0.2784 0.5090
SRP064894 ADAL 161823 RNAseq -0.2065 0.2487
SRP133303 ADAL 161823 RNAseq -0.0004 0.9981
SRP159526 ADAL 161823 RNAseq 0.2761 0.5206
SRP193095 ADAL 161823 RNAseq -0.0799 0.4903
SRP219564 ADAL 161823 RNAseq -0.3559 0.2715
TCGA ADAL 161823 RNAseq -0.0837 0.3269

Upregulated datasets: 0; Downregulated datasets: 0.  

 

Survival by ADAL expression:

 

GSE53622GSE53624TCGA

 

Note: Click image to view full size file.  

Copy number change of ADAL:

 

Dataset Gene EntrezID Gain Loss Normal Detail
GSE15526 ADAL 161823 4 4 22
GSE20123 ADAL 161823 4 5 21
GSE43470 ADAL 161823 3 5 35
GSE46452 ADAL 161823 3 7 49
GSE47630 ADAL 161823 8 10 22
GSE54993 ADAL 161823 4 6 60
GSE54994 ADAL 161823 5 7 41
GSE60625 ADAL 161823 4 0 7
GSE74703 ADAL 161823 3 3 30
GSE74704 ADAL 161823 3 2 15
TCGA ADAL 161823 12 17 67

Total number of gains: 53; Total number of losses: 66; Total Number of normals: 369.  

 

Somatic mutations of ADAL:

 

Generating mutation plots.

 

Highly correlated genes for ADAL:

 

Showing top 20/240 corelated genes with mean PCC>0.5.
Gene1 Gene2 Mean PCC Num. Datasets Num. PCC<0 Num. PCC>0.5
ADALZMAT40.770285303
ADALPACRG0.740556303
ADALRNF1480.720764303
ADALTRAK10.716728303
ADALZER10.702628303
ADALIL17D0.696802303
ADALFAM149A0.693518303
ADALARHGEF250.689801404
ADALSOX100.688865303
ADALNACC20.679525303
ADALMAFF0.670771303
ADALSTBD10.669928303
ADALVPS13D0.669096303
ADALNLRP120.667728303
ADALTMEM1140.667035404
ADALRAVER20.66202404
ADALSPAG80.660306303
ADALUBXN100.65929303
ADALARRB10.658126404
ADALSCN4B0.656428604

For details and further investigation, click here