| Full name: pantothenate kinase 4 | Alias Symbol: FLJ10782 | ||
| Type: protein-coding gene | Cytoband: 1p36.32 | ||
| Entrez ID: 55229 | HGNC ID: HGNC:19366 | Ensembl Gene: ENSG00000157881 | OMIM ID: 606162 |
| Drug and gene relationship at DGIdb | |||
Expression of PANK4:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | PANK4 | 55229 | 218771_at | 0.3948 | 0.3351 | |
| GSE20347 | PANK4 | 55229 | 218771_at | 0.4198 | 0.0088 | |
| GSE23400 | PANK4 | 55229 | 218771_at | 0.1293 | 0.0193 | |
| GSE26886 | PANK4 | 55229 | 218771_at | 0.6933 | 0.0180 | |
| GSE29001 | PANK4 | 55229 | 218771_at | 0.5068 | 0.0010 | |
| GSE38129 | PANK4 | 55229 | 218771_at | 0.3290 | 0.0706 | |
| GSE45670 | PANK4 | 55229 | 218771_at | 0.2837 | 0.0118 | |
| GSE53622 | PANK4 | 55229 | 131997 | 0.2554 | 0.0228 | |
| GSE53624 | PANK4 | 55229 | 131997 | 0.3473 | 0.0129 | |
| GSE63941 | PANK4 | 55229 | 218771_at | 0.3504 | 0.4025 | |
| GSE77861 | PANK4 | 55229 | 218771_at | 0.2398 | 0.3055 | |
| GSE97050 | PANK4 | 55229 | A_23_P149690 | 0.0315 | 0.9020 | |
| SRP007169 | PANK4 | 55229 | RNAseq | -0.3404 | 0.3871 | |
| SRP008496 | PANK4 | 55229 | RNAseq | -0.0821 | 0.7697 | |
| SRP064894 | PANK4 | 55229 | RNAseq | 0.6193 | 0.0000 | |
| SRP133303 | PANK4 | 55229 | RNAseq | 0.3287 | 0.0766 | |
| SRP159526 | PANK4 | 55229 | RNAseq | 0.3817 | 0.1981 | |
| SRP193095 | PANK4 | 55229 | RNAseq | 0.4299 | 0.0001 | |
| SRP219564 | PANK4 | 55229 | RNAseq | -0.0657 | 0.8540 | |
| TCGA | PANK4 | 55229 | RNAseq | -0.1021 | 0.0630 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by PANK4 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of PANK4:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | PANK4 | 55229 | 4 | 6 | 20 | |
| GSE20123 | PANK4 | 55229 | 4 | 5 | 21 | |
| GSE43470 | PANK4 | 55229 | 3 | 5 | 35 | |
| GSE46452 | PANK4 | 55229 | 7 | 1 | 51 | |
| GSE47630 | PANK4 | 55229 | 8 | 4 | 28 | |
| GSE54993 | PANK4 | 55229 | 3 | 2 | 65 | |
| GSE54994 | PANK4 | 55229 | 15 | 2 | 36 | |
| GSE60625 | PANK4 | 55229 | 0 | 0 | 11 | |
| GSE74703 | PANK4 | 55229 | 3 | 3 | 30 | |
| GSE74704 | PANK4 | 55229 | 4 | 0 | 16 | |
| TCGA | PANK4 | 55229 | 14 | 20 | 62 |
Total number of gains: 65; Total number of losses: 48; Total Number of normals: 375.
Somatic mutations of PANK4:
Generating mutation plots.
Highly correlated genes for PANK4:
Showing top 20/1036 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| PANK4 | ZBED1 | 0.799232 | 3 | 0 | 3 |
| PANK4 | ECSIT | 0.789924 | 3 | 0 | 3 |
| PANK4 | ZNF830 | 0.781988 | 3 | 0 | 3 |
| PANK4 | MCCC1 | 0.770473 | 3 | 0 | 3 |
| PANK4 | CCDC150 | 0.76145 | 3 | 0 | 3 |
| PANK4 | ZNF496 | 0.750034 | 4 | 0 | 4 |
| PANK4 | NEURL1B | 0.748047 | 3 | 0 | 3 |
| PANK4 | THAP8 | 0.747786 | 3 | 0 | 3 |
| PANK4 | TMTC4 | 0.747047 | 3 | 0 | 3 |
| PANK4 | TTLL1 | 0.742849 | 3 | 0 | 3 |
| PANK4 | GTPBP6 | 0.740038 | 4 | 0 | 4 |
| PANK4 | ZXDA | 0.738691 | 3 | 0 | 3 |
| PANK4 | PSEN2 | 0.732903 | 3 | 0 | 3 |
| PANK4 | DDX18 | 0.731247 | 4 | 0 | 3 |
| PANK4 | WDR5 | 0.731173 | 3 | 0 | 3 |
| PANK4 | EP400 | 0.730518 | 4 | 0 | 3 |
| PANK4 | FAM161A | 0.730152 | 3 | 0 | 3 |
| PANK4 | NOM1 | 0.729553 | 3 | 0 | 3 |
| PANK4 | CHD6 | 0.728707 | 3 | 0 | 3 |
| PANK4 | CHML | 0.722079 | 3 | 0 | 3 |
For details and further investigation, click here
