| Full name: nuclear autoantigenic sperm protein | Alias Symbol: FLB7527|FLJ31599|FLJ35510|MGC19722|MGC20372|MGC2297|DKFZp547F162|PRO1999 | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 4678 | HGNC ID: HGNC:7644 | Ensembl Gene: ENSG00000132780 | OMIM ID: 603185 |
| Drug and gene relationship at DGIdb | |||
Screen Evidence:
| |||
Expression of NASP:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | NASP | 4678 | 201970_s_at | 0.8453 | 0.0402 | |
| GSE20347 | NASP | 4678 | 201970_s_at | 1.0265 | 0.0000 | |
| GSE23400 | NASP | 4678 | 201970_s_at | 0.9737 | 0.0000 | |
| GSE26886 | NASP | 4678 | 201970_s_at | 0.6000 | 0.0128 | |
| GSE29001 | NASP | 4678 | 201970_s_at | 0.8396 | 0.1150 | |
| GSE38129 | NASP | 4678 | 201970_s_at | 0.9465 | 0.0000 | |
| GSE45670 | NASP | 4678 | 201970_s_at | 0.4187 | 0.0137 | |
| GSE53622 | NASP | 4678 | 105188 | 0.6192 | 0.0000 | |
| GSE53624 | NASP | 4678 | 105188 | 1.0313 | 0.0000 | |
| GSE63941 | NASP | 4678 | 201970_s_at | 1.5942 | 0.0009 | |
| GSE77861 | NASP | 4678 | 201970_s_at | 0.8964 | 0.0272 | |
| GSE97050 | NASP | A_19_P00811284 | 0.1182 | 0.5443 | ||
| SRP007169 | NASP | 4678 | RNAseq | 1.2854 | 0.0067 | |
| SRP008496 | NASP | 4678 | RNAseq | 0.9488 | 0.0058 | |
| SRP064894 | NASP | 4678 | RNAseq | 0.8964 | 0.0000 | |
| SRP133303 | NASP | 4678 | RNAseq | 0.6215 | 0.0001 | |
| SRP159526 | NASP | 4678 | RNAseq | 0.7837 | 0.0571 | |
| SRP193095 | NASP | 4678 | RNAseq | 0.6173 | 0.0000 | |
| SRP219564 | NASP | 4678 | RNAseq | 0.9617 | 0.0022 | |
| TCGA | NASP | 4678 | RNAseq | 0.2219 | 0.0000 |
Upregulated datasets: 4; Downregulated datasets: 0.
Survival by NASP expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of NASP:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | NASP | 4678 | 4 | 3 | 23 | |
| GSE20123 | NASP | 4678 | 4 | 2 | 24 | |
| GSE43470 | NASP | 4678 | 7 | 2 | 34 | |
| GSE46452 | NASP | 4678 | 2 | 1 | 56 | |
| GSE47630 | NASP | 4678 | 9 | 3 | 28 | |
| GSE54993 | NASP | 4678 | 0 | 1 | 69 | |
| GSE54994 | NASP | 4678 | 12 | 2 | 39 | |
| GSE60625 | NASP | 4678 | 0 | 0 | 11 | |
| GSE74703 | NASP | 4678 | 6 | 1 | 29 | |
| GSE74704 | NASP | 4678 | 2 | 0 | 18 | |
| TCGA | NASP | 4678 | 11 | 16 | 69 |
Total number of gains: 57; Total number of losses: 31; Total Number of normals: 400.
Somatic mutations of NASP:
Generating mutation plots.
Highly correlated genes for NASP:
Showing top 20/1864 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| NASP | DYRK2 | 0.797698 | 3 | 0 | 3 |
| NASP | SFMBT1 | 0.789278 | 3 | 0 | 3 |
| NASP | PRPF4B | 0.772425 | 3 | 0 | 3 |
| NASP | USE1 | 0.770897 | 3 | 0 | 3 |
| NASP | EIF3C | 0.770249 | 3 | 0 | 3 |
| NASP | EIF5 | 0.763888 | 3 | 0 | 3 |
| NASP | ISCA1 | 0.76369 | 3 | 0 | 3 |
| NASP | ATXN1L | 0.761808 | 3 | 0 | 3 |
| NASP | MCM3 | 0.759417 | 11 | 0 | 11 |
| NASP | RAVER1 | 0.757905 | 4 | 0 | 4 |
| NASP | MAGOH | 0.753241 | 3 | 0 | 3 |
| NASP | TRPM4 | 0.752774 | 3 | 0 | 3 |
| NASP | ILF3 | 0.751284 | 9 | 0 | 8 |
| NASP | TUBA1B | 0.75093 | 8 | 0 | 8 |
| NASP | MCM6 | 0.745676 | 12 | 0 | 11 |
| NASP | KIF2C | 0.7449 | 12 | 0 | 10 |
| NASP | DNMT1 | 0.744455 | 12 | 0 | 11 |
| NASP | YBX1 | 0.742754 | 9 | 0 | 8 |
| NASP | WDR4 | 0.740921 | 4 | 0 | 4 |
| NASP | NAA30 | 0.740719 | 3 | 0 | 3 |
For details and further investigation, click here
