| Full name: SPT16 homolog, facilitates chromatin remodeling subunit | Alias Symbol: FACT|FACTP140|SPT16/CDC68|FLJ14010|FLJ10857|CDC68 | ||
| Type: protein-coding gene | Cytoband: 14q11.2 | ||
| Entrez ID: 11198 | HGNC ID: HGNC:11465 | Ensembl Gene: ENSG00000092201 | OMIM ID: 605012 |
| Drug and gene relationship at DGIdb | |||
Expression of SUPT16H:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | SUPT16H | 11198 | 217815_at | 0.6725 | 0.1982 | |
| GSE20347 | SUPT16H | 11198 | 217815_at | 1.0244 | 0.0000 | |
| GSE23400 | SUPT16H | 11198 | 217815_at | 0.9339 | 0.0000 | |
| GSE26886 | SUPT16H | 11198 | 217815_at | 0.3401 | 0.1008 | |
| GSE29001 | SUPT16H | 11198 | 217815_at | 1.0978 | 0.0048 | |
| GSE38129 | SUPT16H | 11198 | 217815_at | 0.9254 | 0.0000 | |
| GSE45670 | SUPT16H | 11198 | 217815_at | 0.6617 | 0.0008 | |
| GSE53622 | SUPT16H | 11198 | 56324 | 0.8253 | 0.0000 | |
| GSE53624 | SUPT16H | 11198 | 56324 | 0.8804 | 0.0000 | |
| GSE63941 | SUPT16H | 11198 | 217815_at | 1.0532 | 0.0068 | |
| GSE77861 | SUPT16H | 11198 | 217815_at | 1.2549 | 0.0166 | |
| GSE97050 | SUPT16H | 11198 | A_23_P151634 | 0.4761 | 0.1492 | |
| SRP007169 | SUPT16H | 11198 | RNAseq | 2.1861 | 0.0000 | |
| SRP008496 | SUPT16H | 11198 | RNAseq | 1.9420 | 0.0000 | |
| SRP064894 | SUPT16H | 11198 | RNAseq | 0.7588 | 0.0000 | |
| SRP133303 | SUPT16H | 11198 | RNAseq | 0.8177 | 0.0001 | |
| SRP159526 | SUPT16H | 11198 | RNAseq | 0.8462 | 0.0000 | |
| SRP193095 | SUPT16H | 11198 | RNAseq | 0.7616 | 0.0000 | |
| SRP219564 | SUPT16H | 11198 | RNAseq | 0.6664 | 0.0066 | |
| TCGA | SUPT16H | 11198 | RNAseq | 0.1607 | 0.0005 |
Upregulated datasets: 6; Downregulated datasets: 0.
Survival by SUPT16H expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of SUPT16H:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | SUPT16H | 11198 | 9 | 3 | 18 | |
| GSE20123 | SUPT16H | 11198 | 9 | 3 | 18 | |
| GSE43470 | SUPT16H | 11198 | 7 | 2 | 34 | |
| GSE46452 | SUPT16H | 11198 | 18 | 2 | 39 | |
| GSE47630 | SUPT16H | 11198 | 10 | 10 | 20 | |
| GSE54993 | SUPT16H | 11198 | 3 | 11 | 56 | |
| GSE54994 | SUPT16H | 11198 | 18 | 5 | 30 | |
| GSE60625 | SUPT16H | 11198 | 0 | 2 | 9 | |
| GSE74703 | SUPT16H | 11198 | 6 | 2 | 28 | |
| GSE74704 | SUPT16H | 11198 | 4 | 2 | 14 | |
| TCGA | SUPT16H | 11198 | 27 | 16 | 53 |
Total number of gains: 111; Total number of losses: 58; Total Number of normals: 319.
Somatic mutations of SUPT16H:
Generating mutation plots.
Highly correlated genes for SUPT16H:
Showing top 20/1898 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| SUPT16H | APEX1 | 0.794707 | 13 | 0 | 13 |
| SUPT16H | LINGO1 | 0.781916 | 3 | 0 | 3 |
| SUPT16H | PARP2 | 0.772714 | 13 | 0 | 13 |
| SUPT16H | EXOC6 | 0.768655 | 3 | 0 | 3 |
| SUPT16H | ILF3 | 0.768385 | 8 | 0 | 7 |
| SUPT16H | NGDN | 0.768155 | 13 | 0 | 13 |
| SUPT16H | METTL3 | 0.758303 | 13 | 0 | 13 |
| SUPT16H | METTL17 | 0.74986 | 12 | 0 | 12 |
| SUPT16H | R3HDM1 | 0.748487 | 9 | 0 | 9 |
| SUPT16H | GNG10 | 0.746229 | 3 | 0 | 3 |
| SUPT16H | G2E3 | 0.740973 | 7 | 0 | 6 |
| SUPT16H | ATP6V1C1 | 0.737698 | 10 | 0 | 10 |
| SUPT16H | CEP170 | 0.735536 | 3 | 0 | 3 |
| SUPT16H | ERH | 0.733583 | 13 | 0 | 11 |
| SUPT16H | BOLA3 | 0.733555 | 6 | 0 | 6 |
| SUPT16H | BOD1 | 0.731027 | 6 | 0 | 5 |
| SUPT16H | SLC38A6 | 0.730535 | 9 | 0 | 9 |
| SUPT16H | MZT2B | 0.724402 | 3 | 0 | 3 |
| SUPT16H | PFDN2 | 0.724386 | 10 | 0 | 9 |
| SUPT16H | FZD6 | 0.723899 | 8 | 0 | 8 |
For details and further investigation, click here
