| Full name: ERI1 exoribonuclease family member 3 | Alias Symbol: FLJ22943|PINT1 | ||
| Type: protein-coding gene | Cytoband: 1p34.1 | ||
| Entrez ID: 79033 | HGNC ID: HGNC:17276 | Ensembl Gene: ENSG00000117419 | OMIM ID: 609917 |
| Drug and gene relationship at DGIdb | |||
Expression of ERI3:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERI3 | 79033 | 208973_at | 0.8687 | 0.1318 | |
| GSE20347 | ERI3 | 79033 | 208973_at | 0.9554 | 0.0000 | |
| GSE23400 | ERI3 | 79033 | 208973_at | 0.5029 | 0.0000 | |
| GSE26886 | ERI3 | 79033 | 208973_at | 0.6311 | 0.0010 | |
| GSE29001 | ERI3 | 79033 | 208973_at | 0.1630 | 0.2907 | |
| GSE38129 | ERI3 | 79033 | 208973_at | 0.9383 | 0.0000 | |
| GSE45670 | ERI3 | 79033 | 208973_at | 0.1961 | 0.1308 | |
| GSE53622 | ERI3 | 79033 | 49196 | 0.5937 | 0.0000 | |
| GSE53624 | ERI3 | 79033 | 49196 | 0.8193 | 0.0000 | |
| GSE63941 | ERI3 | 79033 | 208973_at | 2.7259 | 0.0001 | |
| GSE77861 | ERI3 | 79033 | 208973_at | 0.2685 | 0.2216 | |
| GSE97050 | ERI3 | 79033 | A_32_P155416 | 0.1510 | 0.6456 | |
| SRP007169 | ERI3 | 79033 | RNAseq | 0.6135 | 0.1865 | |
| SRP008496 | ERI3 | 79033 | RNAseq | 0.7953 | 0.0196 | |
| SRP064894 | ERI3 | 79033 | RNAseq | 1.0450 | 0.0004 | |
| SRP133303 | ERI3 | 79033 | RNAseq | 0.5596 | 0.0000 | |
| SRP159526 | ERI3 | 79033 | RNAseq | 1.1961 | 0.0003 | |
| SRP193095 | ERI3 | 79033 | RNAseq | 0.6893 | 0.0000 | |
| SRP219564 | ERI3 | 79033 | RNAseq | 0.9214 | 0.0387 | |
| TCGA | ERI3 | 79033 | RNAseq | 0.1932 | 0.0002 |
Upregulated datasets: 3; Downregulated datasets: 0.
Survival by ERI3 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERI3:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERI3 | 79033 | 4 | 3 | 23 | |
| GSE20123 | ERI3 | 79033 | 4 | 2 | 24 | |
| GSE43470 | ERI3 | 79033 | 7 | 2 | 34 | |
| GSE46452 | ERI3 | 79033 | 2 | 1 | 56 | |
| GSE47630 | ERI3 | 79033 | 9 | 3 | 28 | |
| GSE54993 | ERI3 | 79033 | 0 | 1 | 69 | |
| GSE54994 | ERI3 | 79033 | 13 | 2 | 38 | |
| GSE60625 | ERI3 | 79033 | 0 | 0 | 11 | |
| GSE74703 | ERI3 | 79033 | 6 | 1 | 29 | |
| GSE74704 | ERI3 | 79033 | 2 | 0 | 18 | |
| TCGA | ERI3 | 79033 | 14 | 16 | 66 |
Total number of gains: 61; Total number of losses: 31; Total Number of normals: 396.
Somatic mutations of ERI3:
Generating mutation plots.
Highly correlated genes for ERI3:
Showing top 20/1616 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERI3 | CSNK2B | 0.836369 | 3 | 0 | 3 |
| ERI3 | ANKRD54 | 0.814141 | 3 | 0 | 3 |
| ERI3 | PPP5C | 0.812027 | 5 | 0 | 5 |
| ERI3 | ZNF664 | 0.783552 | 3 | 0 | 3 |
| ERI3 | RAB11B | 0.781455 | 3 | 0 | 3 |
| ERI3 | C11orf1 | 0.778515 | 3 | 0 | 3 |
| ERI3 | ANKIB1 | 0.777318 | 3 | 0 | 3 |
| ERI3 | CRTC2 | 0.77676 | 4 | 0 | 4 |
| ERI3 | KLHL36 | 0.748265 | 3 | 0 | 3 |
| ERI3 | TUBA1B | 0.744447 | 8 | 0 | 8 |
| ERI3 | SORL1 | 0.741038 | 3 | 0 | 3 |
| ERI3 | BAG6 | 0.737786 | 4 | 0 | 3 |
| ERI3 | KRTCAP2 | 0.735161 | 5 | 0 | 5 |
| ERI3 | POLDIP2 | 0.729662 | 3 | 0 | 3 |
| ERI3 | YBX1 | 0.72657 | 7 | 0 | 6 |
| ERI3 | INPP5K | 0.723362 | 3 | 0 | 3 |
| ERI3 | AGAP1 | 0.720801 | 3 | 0 | 3 |
| ERI3 | POMGNT1 | 0.719517 | 11 | 0 | 9 |
| ERI3 | TEAD2 | 0.718822 | 4 | 0 | 4 |
| ERI3 | DAG1 | 0.71783 | 4 | 0 | 4 |
For details and further investigation, click here
