| Full name: ER lipid raft associated 1 | Alias Symbol: KE04|Erlin-1|SPG62 | ||
| Type: protein-coding gene | Cytoband: 10q24.31 | ||
| Entrez ID: 10613 | HGNC ID: HGNC:16947 | Ensembl Gene: ENSG00000107566 | OMIM ID: 611604 |
| Drug and gene relationship at DGIdb | |||
Expression of ERLIN1:
| Dataset | Gene | EntrezID | Probe | Log2FC | Adj.pValue | Expression |
|---|---|---|---|---|---|---|
| GSE17351 | ERLIN1 | 10613 | 202441_at | 0.1605 | 0.7917 | |
| GSE20347 | ERLIN1 | 10613 | 202441_at | -0.5456 | 0.0002 | |
| GSE23400 | ERLIN1 | 10613 | 202441_at | -0.2055 | 0.0074 | |
| GSE26886 | ERLIN1 | 10613 | 202441_at | -0.8914 | 0.0000 | |
| GSE29001 | ERLIN1 | 10613 | 202441_at | -0.4815 | 0.0358 | |
| GSE38129 | ERLIN1 | 10613 | 202441_at | -0.1503 | 0.3771 | |
| GSE45670 | ERLIN1 | 10613 | 202441_at | -0.1157 | 0.2683 | |
| GSE53622 | ERLIN1 | 10613 | 156289 | -0.2708 | 0.0022 | |
| GSE53624 | ERLIN1 | 10613 | 156289 | -0.5291 | 0.0000 | |
| GSE63941 | ERLIN1 | 10613 | 202441_at | -0.6165 | 0.0576 | |
| GSE77861 | ERLIN1 | 10613 | 202441_at | -0.3509 | 0.0965 | |
| GSE97050 | ERLIN1 | 10613 | A_23_P52219 | 0.6658 | 0.2852 | |
| SRP007169 | ERLIN1 | 10613 | RNAseq | -0.4287 | 0.1860 | |
| SRP008496 | ERLIN1 | 10613 | RNAseq | 0.0199 | 0.9394 | |
| SRP064894 | ERLIN1 | 10613 | RNAseq | -0.6209 | 0.0000 | |
| SRP133303 | ERLIN1 | 10613 | RNAseq | -0.2126 | 0.0684 | |
| SRP159526 | ERLIN1 | 10613 | RNAseq | -0.5138 | 0.1095 | |
| SRP193095 | ERLIN1 | 10613 | RNAseq | -0.4477 | 0.0001 | |
| SRP219564 | ERLIN1 | 10613 | RNAseq | -0.1617 | 0.7316 | |
| TCGA | ERLIN1 | 10613 | RNAseq | 0.0245 | 0.6500 |
Upregulated datasets: 0; Downregulated datasets: 0.
Survival by ERLIN1 expression:
 |  |  |
| GSE53622 | GSE53624 | TCGA |
Note: Click image to view full size file.
Copy number change of ERLIN1:
| Dataset | Gene | EntrezID | Gain | Loss | Normal | Detail |
|---|---|---|---|---|---|---|
| GSE15526 | ERLIN1 | 10613 | 1 | 8 | 21 | |
| GSE20123 | ERLIN1 | 10613 | 1 | 7 | 22 | |
| GSE43470 | ERLIN1 | 10613 | 0 | 7 | 36 | |
| GSE46452 | ERLIN1 | 10613 | 0 | 11 | 48 | |
| GSE47630 | ERLIN1 | 10613 | 2 | 14 | 24 | |
| GSE54993 | ERLIN1 | 10613 | 8 | 0 | 62 | |
| GSE54994 | ERLIN1 | 10613 | 1 | 12 | 40 | |
| GSE60625 | ERLIN1 | 10613 | 0 | 0 | 11 | |
| GSE74703 | ERLIN1 | 10613 | 0 | 5 | 31 | |
| GSE74704 | ERLIN1 | 10613 | 0 | 4 | 16 | |
| TCGA | ERLIN1 | 10613 | 5 | 28 | 63 |
Total number of gains: 18; Total number of losses: 96; Total Number of normals: 374.
Somatic mutations of ERLIN1:
Generating mutation plots.
Highly correlated genes for ERLIN1:
Showing top 20/571 corelated genes with mean PCC>0.5.
| Gene1 | Gene2 | Mean PCC | Num. Datasets | Num. PCC<0 | Num. PCC>0.5 |
|---|---|---|---|---|---|
| ERLIN1 | WDFY1 | 0.73226 | 4 | 0 | 4 |
| ERLIN1 | PDIK1L | 0.726456 | 4 | 0 | 4 |
| ERLIN1 | SLC35B1 | 0.705262 | 5 | 0 | 5 |
| ERLIN1 | MLKL | 0.704336 | 3 | 0 | 3 |
| ERLIN1 | AP3M1 | 0.686235 | 4 | 0 | 3 |
| ERLIN1 | MTFR1L | 0.680092 | 3 | 0 | 3 |
| ERLIN1 | MOV10 | 0.669182 | 3 | 0 | 3 |
| ERLIN1 | P4HB | 0.663131 | 7 | 0 | 6 |
| ERLIN1 | STK38 | 0.65592 | 4 | 0 | 3 |
| ERLIN1 | MECOM | 0.649558 | 4 | 0 | 4 |
| ERLIN1 | ITPRIPL2 | 0.649303 | 3 | 0 | 3 |
| ERLIN1 | ATP6V0C | 0.646002 | 6 | 0 | 5 |
| ERLIN1 | CCDC115 | 0.645167 | 3 | 0 | 3 |
| ERLIN1 | ASL | 0.641601 | 7 | 0 | 7 |
| ERLIN1 | TMEM254 | 0.637294 | 10 | 0 | 9 |
| ERLIN1 | ARL6IP5 | 0.637056 | 5 | 0 | 5 |
| ERLIN1 | THAP2 | 0.636672 | 4 | 0 | 3 |
| ERLIN1 | SNX24 | 0.635176 | 8 | 0 | 7 |
| ERLIN1 | CHPT1 | 0.633502 | 4 | 0 | 4 |
| ERLIN1 | PRMT6 | 0.629303 | 3 | 0 | 3 |
For details and further investigation, click here
